Apicomplexan parasite
mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway
... any apicomplexan parasite genome [71], prompting the ques- tion of how ...in apicomplexan parasites have been reviewed [71], and with the exception of the Ran GAP protein, apicomplexans appear to ...
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Fatal infection with emerging apicomplexan parasite Hepatozoon silvestris in a domestic cat
... emerging apicomplexan parasite discovered in European wild cats from Bosnia and Herzegovina and blood samples of a domestic cat from Southern Italy in ...
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Aminopeptidase N1 (EtAPN1), an M1 Metalloprotease of the Apicomplexan Parasite Eimeria tenella, Participates in Parasite Development
... (Table 1). EtAPN1r showed a slightly higher affinity than PfA-M1r FIG 4 Comparison of aminopeptidases N with Eimeria EtAPN1. Multiple-sequence alignment of the active site (boxed region) and the flanking amino acid ...
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Eimeripain, a cathepsin b-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella
... only one in sporulated oocysts. CP-dependant activities were found against the fluorescent substrates, Z-FR-AMC and Z-LR- AMC, throughout the sporulation process. These activities corresponded to a cathepsin B-like ...
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Receptor for Retrograde Transport in the Apicomplexan Parasite Toxoplasma gondii
... the parasite Golgi ...the parasite nucleus (yellow arrows) with some staining in the nuclear envelope and ER (the model for organelle orientation is shown in panel ...The parasite Golgi apparatus (G) ...
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Multiple Functionally Redundant Signals Mediate Targeting to the Apicoplast in the Apicomplexan Parasite Toxoplasma gondii
... example, apicomplexan parasites, including Plasmodium species (which cause ⬃500 million cases of human malaria annually, resulting in 2 to 3 million deaths [36, 58]), Toxoplasma gondii (which can lead to severe ...
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Host-Apicomplexan Parasite Interactions: Leveraging Biological Discovery into Antiparasitic Drug Development
... for parasite-mediated ...highlighted parasite proteins that interact with the host cell during this cycle, host proteins exploited by the parasite for successful growth and conversely, host molecules ...
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Mitochondrial genome of Babesia orientalis, apicomplexan parasite of water buffalo (Bubalus babalis, Linnaeus, 1758) endemic in China
... The blood from experimentally infected buffalo was col- lected in EDTA. Parasite genomic DNA was extracted from B. orientalis-infected blood using QIAamp DNA Blood Mini Kit (Qiagen, Hilden, Germany) according to ...
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Stage-specific expression of protease genes in the apicomplexan parasite, Eimeria tenella
... against apicomplexan genome sequence databases and against vari- ous protein databases [32] such as the protein data bank (PDB), Swiss-Prot and non-redundant (NR) protein se- quence ...
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The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates
... an apicomplexan parasite that causes enteritis and diarrhea in suckling piglets and economic losses in pig production ...the apicomplexan-specific secretory organelles including AMA1, MIC6, MIC13, ...
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Investigation of infectivity of neonates and adults from different rat strains to toxoplasma gondii prugniaud shows both variation which correlates with iNOS and Arginase 1 activity and increased susceptibility of neonates to infection
... Keywords: Toxoplasma gondii Prugniaud strain; cyst; neonate rats; host resistance; iNOS;... Toxoplasma gondii is an obligatory intracellular apicomplexan parasite that infects.[r] ...
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Three dimensional visualisation of developmental stages of an apicomplexan fish blood parasite in its invertebrate host
... Despite being used widely in medicine, for example, in displaying Magnetic Resonance Images [20-22], the use of 3D visualisation in parasitology, particularly using brightfield and confocal images, appears limited to ...
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Study of Blood Parasites of the Three Snake Species in Iran: Natrix natrix, Natrix tessellata and Zamenis longissimus (Colubridae)
... of Apicomplexan haemoparasites, which widely distributed in reptiles (Telford, ...widespread Apicomplexan parasite infecting different species of snakes and lizards (Cook et ...
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Using a genetically encoded sensor to identify inhibitors of Toxoplasma gondii Ca2+ Signalling
... Enh1 Inhibits T. gondii Survival—Zaprinast and related phosphodiesterase inhibitors were recently shown to block T. gondii proliferation in human fibroblasts (61). Altering Ca 2⫹ levels using ionophores has also been ...
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An investigation into the host parasite interrelationship between Common Swifts and Hippoboscid Louse Flies
... Flies from individual nests were all marked identically on their atrophied wings using acrylic paint. Through the use of different colours and through marking either left or right wings, flies from separate nests could ...
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New Opportunities in the Structure-based Design of Anti-Protozoan Agents.
... and Cryptosporidium [68]. Whilst apicomplexans contain a diverse family of CDPKs, several individual protein kinases such as CDPK1 and CDPK4 have important roles [69]. Kato et al. [70] determined that the pfcdpk1 gene ...
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Genetic characterization of Hawaiian isolates of Plasmodium relictumreveals mixed-genotype infections
... The trap gene encodes a cell-surface protein present in sporozoites and erythrocytic stage malaria parasites and was first described by Robson et al. [7]. The TRAP protein is critical for gliding motility (a unique ...
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Dynamics and Fate of the inner Membrane Complex in Apicomplexan Parasites
... of apicomplexan parasites drives interest in their many evolutionary ...in parasite motility, invasion, metabolism, and replication, and understanding their relationship with the organelles of better- ...
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An Epidemiological, Diagnostic, and Therapeutic Study of the Leishmania tropica Parasite in Iraq’s Anbar Province Suad Shallal Shahatha* Thaer Abdelqader Saleh
... tropica parasite specifically in the province of Anbar and the spread of the ailment epidemically, particularly in light of the province’s political conditions over the past two years and considering the ...
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Make It or Take It: Fatty Acid Metabolism of Apicomplexan Parasites
... The most recent model for fatty acid uptake emerged from expression profiling along the Plasmodium life cycle. This work has identified numerous genes that are upregulated in the infective sporozoite (UIS) compared to ...
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