apo, apolipoprotein
Donor splice site mutation in the apolipoprotein (Apo) C II gene (Apo C IIHamburg) of a patient with Apo C II deficiency
... of apo C-II have been analyzed in a patient with apo C-II deficiency (apo ...C-II apolipoprotein were demonstrated by immunoblotting and immunohistochemical ...normal-sized apo C-II ...
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Serum prostacyclin stabilizing factor is identical to apolipoprotein A I (Apo A I) A novel function of Apo A I
... human apolipoprotein A-I (Apo A-I), a major apolipoprotein of ...HDL. Apolipoprotein A-II, C-I, C-II, C-III, D and E, as well as LDL, and VLDL did not possess this ...of Apo A-I is ...
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Paediatric dyslipidemia as a predictor of dyslipidemia and carotid artery thickening in young adults : findings from the Childhood Determinants of Adult Health (CDAH) Study, the Cardiovascular Risk in Young Finns Study, and the Bogalusa Heart Study
... ABBREVIATIONS AAP = American Academy of Pediatrics AHA = American Heart Association apo = apolipoprotein ARIC = Atherosclerosis Risk in Communities ARMY = Atherosclerosis Risk-Factors in[r] ...
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The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels
... HeFH heterozygotes for familial hypercholesterolemia, HoFH homozygotes for familial hypercholesterolemia, C cholesterol; apo: apolipoprotein, PCSK9 proprotein convertase subtilisin/kexin[r] ...
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Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo
... bear apo B-100 and apo E bind to urate crystals and suppress crystal-neutrophil ...with apo E of monocyte origin, had a diminished ability to stimulate ...neutrophils. Apo E was also detected ...
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Association between single nucleotide polymorphism rs11057401 of CCDC92 gene and the risk of coronary heart disease (CHD)
... covariance; Apo: Apolipoprotein; ApoA1: Apolipoprotein A1; ApoB: Apolipoprotein B; BMI: Body mass index; CCDC92: Coiled-coil domain containing 92; CHD: Coronary heart disease; FPG: Fasting ...
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Lipoprotein lipase activity and mass, apolipoprotein C-II mass and polymorphisms of apolipoproteins E and A5 in subjects with prior acute hypertriglyceridaemic pancreatitis
... of apolipoprotein C-II in persons who had survived at least one episode of hyper- triglyceridaemic pancreatitis in comparison with persons who were at risk for the same disorder due to having severe ...
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Apolipoprotein E2 Christchurch (136 Arg Ser) New variant of human apolipoprotein E in a patient with type III hyperlipoproteinemia
... normal apo E3 map by the altered mobility of a single ...that apo E2 in these patients had a substitution of 158 ...common apo E2 (158 Arg---- Cys) ...more apo E2 (136 Arg----Ser) than ...
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Structural relationship of human apolipoprotein B48 to apolipoprotein B100
... human apolipoprotein (apo) B100 is known (4536 amino acids), the structure of apo B48 has not been ...of apo B48 and its relationship to apo ...human apo B100. The levels of ...
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Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal study
... the apo(a) portion of Lp(a) and circulating Lp(a) concentrations; [5, 19, 20] but be- cause the Lp(a) assay used in this current study is not sen- sitive to apolipoprotein(a) isoform size, we are not able ...
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Hypertriglyceridemia and cholesteryl ester transfer protein interact to dramatically alter high density lipoprotein levels, particle sizes, and metabolism Studies in transgenic mice
... human apo CIII transgenic mice lowered HDL-cholesterol (HDL-C) 48% and apolipoprotein (apo) A-I 40%, decreased HDL size (particle diameter from ...increased apo A-I FCR 15% and decreased ...
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Epitopes of apolipoprotein B 100 and B 48 in both liver and intestine Expression and evidence for local synthesis in recessive abetalipoproteinemia
... microscopy, apo B was found to be present in the smooth endoplasmatic reticulum and the Golgi ...and apo B was present in the Golgi ...expressed apo B-48 and B-100 epitopes, which indicates ...
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IMMUNOGENETIC POLYMORPHISM OF LIPOPROTEINS IN SWINE: GENETIC, IMMUNOLOGICAL AND PHYSIOCHEMICAL CHARACTERIZATION OF THE TWO ALLOTYPES LPR1 AND LPR2
... However, the essential role of the protein moiety of lipoproteins, designated apolipoprotein (apo) (ROHEIM, MILLER and EDER 1965), in the formation of lipoprotein [r] ...
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Apo E structure determines VLDL clearance and atherosclerosis risk in mice
... human apo E4 isoform in place of the endogenous murine apo E protein and have compared them with mice expressing the human apo E3 ...and apolipoprotein levels in the mice expressing only the ...
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Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects
... normolipidemic apo E2/2 homozygotes and 5 familial hypercholesterolemic ...the apo E2/2 homozygotes, indicative of an important degree of flux control exerted by a receptor-mediated step involving ...
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Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice
... Abbreviations SGLT2: sodium glucose co-transporter2; SGLT2i: sodium glucose co-trans‑ porter2 inhibitor; T2DM: type 2 diabetes mellitus; Apo-E−/−: apolipoprotein E knockout Apo-E−/−; CVD[r] ...
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New mutants of apolipoprotein E associated with atherosclerotic diseases but not to type III hyperlipoproteinemia
... individuals. Apo E gene frequencies in the group of healthy individuals were comparable with those in German and American ...common apo E phenotypes in the groups of hyperlipidemia and ischemic heart ...
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Immune complex hyperlipidemia induced by an apolipoprotein reactive immunoglobulin A paraprotein from a patient with multiple myeloma Characterization of this immunoglobulin
... to apolipoprotein B (apo B)- containing lipoproteins that formed macromolecular aggregates, and globules thought to be aggregated complexes of lipoproteins and reactive immunoglobulins were ...
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Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor
... the apolipoprotein CIII (apo CIII) concentration medi- ated transcriptionally by peroxisome proliferator activated receptor (PPAR) ...in apolipoprotein CIII reduces the inhibition of LpL ...
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Development of an integrated model for analysis of the kinetics of apolipoprotein B in plasma very low density lipoproteins, intermediate density lipoproteins, and low density lipoproteins
... circulation, and (d) a two-compartment subsystem for LDL. Because mass data indicate that not all VLDL were converted to LDL, the model allows for irreversible removal of apo B from VLDL (or IDL) subsystems. It ...
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