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Apoptotic Index

Evaluating the Importance of Apoptotic  Index, Mitotic Index and Turnover Index in Premalignant and Malignant Lesions of  Cervix

Evaluating the Importance of Apoptotic Index, Mitotic Index and Turnover Index in Premalignant and Malignant Lesions of Cervix

... the apoptotic index (AI), mitotic index (MI) and turnover index of the ...lens. Apoptotic index (AI) was calculated as the number of Apoptotic cells and Apoptotic ...

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Oxytocin can decrease germ cells apoptotic index in testis under acute ischemia reperfusion in a rat model

Oxytocin can decrease germ cells apoptotic index in testis under acute ischemia reperfusion in a rat model

... Materials and Methods: 20 adult rats were randomly divided into four groups: Control, IR, OT and IR+ OT (OTA). Testicular ischemia was achieved by 720° torsion of the left testis for 2 hr. Then, torsion was removed and ...

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Evaluation of Ki 67 proliferation and apoptotic index before, during and after neoadjuvant chemotherapy for primary breast cancer

Evaluation of Ki 67 proliferation and apoptotic index before, during and after neoadjuvant chemotherapy for primary breast cancer

... Ki-67 index has been demonstrated ...proliferation index of individual ...of apoptotic cells in tumour sections may be measured by labeling fragmented DNA breaks and calculating the apoptotic ...

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Clinicopathological study of premalignant and malignant lesions of cervix along with apoptotic index and Ki-67 expression

Clinicopathological study of premalignant and malignant lesions of cervix along with apoptotic index and Ki-67 expression

... in apoptotic index (Figure 1) was observed from keratinizing squamous cell carcinoma ...mean Apoptotic index for adenocarcinoma is ...shows Apoptotic index of 1.2. Overall mean ...

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Apoptotic Index of Amniotic Membrane Cells in Preterm Labor with Premature Rupture of Membrane (PPROM) was Higher than Preterm Labor without Premature Rupture of Membrane

Apoptotic Index of Amniotic Membrane Cells in Preterm Labor with Premature Rupture of Membrane (PPROM) was Higher than Preterm Labor without Premature Rupture of Membrane

... the apoptotic index of amniotic membrane cells in preterm labor with premature rupture of membrane (PPROM) and without premature rupture of ...then apoptotic index was measured by TUNEL ...the ...

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Demodex Folliculorum in Cutaneous Biopsy:  A Histological Surprise

Demodex Folliculorum in Cutaneous Biopsy: A Histological Surprise

... intensity of bcl-2 expression was inversely related to apoptotic index. From this study, it is postulated that there is gradual increase in the extent of apoptosis and a decrease in bcl-2 expression in ...

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Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3β dependent pathway in experimental diabetic cardiomyopathy

Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3β dependent pathway in experimental diabetic cardiomyopathy

... In the present study, TSN attenuates cardiac systolic and diastolic dysfunction in experimental diabetic cardio- myopathy. TSN treated rats had significantly smaller LVEDV and LVESV increases and LVEF decrease 12 w after ...

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Mitotic and apoptotic activity in colorectal neoplasia

Mitotic and apoptotic activity in colorectal neoplasia

... mitotic index [mitotic index (%) = number of mitotic fig- ures × 100 / number of all evaluated cells] and grade of apoptosis, conveyed as an apoptotic index [apoptotic index (%) ...

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... on apoptotic index in early and advanced stage, and it was not statistically significant but there was an increase in apoptotic index after administration of ...increasing apoptotic ...

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Protective Effect of Tribulus Terrestris Hydroalcoholic Extract against Cisplatin – Induce Apoptisis on Testis in Mice

Protective Effect of Tribulus Terrestris Hydroalcoholic Extract against Cisplatin – Induce Apoptisis on Testis in Mice

... ml-1). Apoptotic index (AI) was calculated by dividing the number of TUNEL-positive cells to total number of the cells in randomly focused fields, and the result was multiplied by 100 ...

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Neuroprotective effect of resveratrol in diabetic cerebral ischemic-reperfused rats through regulation of inflammatory and apoptotic events

Neuroprotective effect of resveratrol in diabetic cerebral ischemic-reperfused rats through regulation of inflammatory and apoptotic events

... The current study showed that cerebral ischemic- reperfusion for diabetic rats specifically exaggerated oxi- dative stress, inflammation and apoptosis including a significant increase of cerebral content of MDA, upregu- ...

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Proliferation Index: A Continuous Model to Predict Prognosis in Patients with Tumours of the Ewing's Sarcoma Family

Proliferation Index: A Continuous Model to Predict Prognosis in Patients with Tumours of the Ewing's Sarcoma Family

... proliferation index (PI) and apoptotic index (AI), caspase-8, -9 and -10 expression have been investigated in primary Ewing’s sarcoma family of tumours ...0–87). Apoptotic cells, identified ...

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To die or to differentiate: apoptotic and non apoptotic roles of death molecules in Drosophila melanogaster

To die or to differentiate: apoptotic and non apoptotic roles of death molecules in Drosophila melanogaster

... Unlike apoptotic cell death, where macrophage mediated corpse engulfment takes place, autophagic vacules are ultimately targeted to the lysosome inside dying cells for ...

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Lung and 'end organ' injury due to mechanical ventilation in animals: comparison between the prone and supine positions

Lung and 'end organ' injury due to mechanical ventilation in animals: comparison between the prone and supine positions

... The main limitations of this study are that the measure of solu- ble pre-apoptotic and apoptosis-inducing factors was not pos- sible and that only a single method (TUNEL) was used to confirm apoptosis. TUNEL is a ...

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Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death

Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death

... cell types, including epithelial cells, endothelial cells, neurons, and lymphocytes [18, 40]. We next investigated the impact of siRNA-mediated Bim inhibition on the apoptosis of IGROV1 and IGROV1-R10 cells, in re- ...

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Nitric oxide-associated chondrocyte apoptosis in trauma patients after high-energy lower extremity intra-articular fractures

Nitric oxide-associated chondrocyte apoptosis in trauma patients after high-energy lower extremity intra-articular fractures

... In conclusion, we found the percentage of cells with apoptosis is increased in cartilage from trauma patients, and that those cells are more likely to contain NO, impli- cating NO-induced apoptosis after intra-articular ...

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Is disturbed clearance of apoptotic keratinocytes responsible for UVB induced inflammatory skin lesions in systemic lupus erythematosus?

Is disturbed clearance of apoptotic keratinocytes responsible for UVB induced inflammatory skin lesions in systemic lupus erythematosus?

... Development of infiltrates and inflammatory lesions in patients with SLE after irradiation and in LE skin lesions To study the inflammatory response induced by a single dose of UVB irradiation, skin biopsies were taken ...

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Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

... of apoptotic cells using the transferase- mediated biotin-dUTP nick end-labeling (TUNEL) reac- tion with Klenow terminal deoxynucleotidyl transferase (Oncogene Research Products, Cambridge, Massachu- setts, USA), ...

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Efferocytosis in Retinoblastoma

Efferocytosis in Retinoblastoma

... of apoptotic ch- anges in a unilateral, undifferentiated and untreated case of retinoblastoma were seen where nuclear fragmentation and apoptotic vesicle arrangement were realized and macrophages in the ...

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Neonatal Hypoxic-Ischemic Brain Injury: Apoptotic and Non-Apoptotic Cell Death

Neonatal Hypoxic-Ischemic Brain Injury: Apoptotic and Non-Apoptotic Cell Death

... The neuronal cell death associated with perinatal asphyxia, or hypoxic- ischemic (HI) brain injury, plays an important role in neonatal mortality and neurodevelopment retardation. The types of cell death associated with ...

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