Appendix 1: The human myostatin growth factor
Production and functional characterization of human insulin-like growth factor 1
... Insulin-like growth factor 1 (IGF-1) is a polypeptide hormone produced mainly by the liver in response to the endocrine growth hormone (GH) ...study, human heart cDNA was ...
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Optimization and Construction of Human Insulin-like Growth Factor 1 Gene related to human health
... use of its system in diseases related to such as severe shortage of primary IGF, like Laron syndrome, reduced effect of growth hormone, idiopathic short stature, wasting syndrome. 4 The most of reported cases of ...
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The Role of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 in Human Esophageal Cancer
... Insulin-like growth factors (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) play important roles in cell growth and ...
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Hepatocyte Growth Factor Suppresses Transforming Growth Factor-Beta-1 and Type III Collagen in Human Primary Renal Fibroblasts
... Emerging evidence [13,14] suggests that the HGF/ c-Met axis is an important component of the intercel- lular signaling pathway that controls the growth and differentiation of diverse types of cells. HGF not only ...
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Endothelin 1 is an autocrine/paracrine growth factor for human cancer cell lines
... We studied whether a novel vasoconstrictor peptide, endothelin-1 (ET-1), is synthesized by and released from human carcinoma cell lines, and whether ET-1 stimulates proliferation of these ...
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Role of insulin-like growth factor binding protein 1 in human pregnancy
... Mouse models There have been no reports of mice carrying a null mutation for IGFBP-1, and IGFBP-1 transgenic mice have not proved to be particularly useful in determining the role of IGFBP-1 in preg- ...
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Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2 induced catabolic activities in human articular chondrocytes
... FGFR3, as well as comparisons between FGF-2 versus FGF-18 treatments. Published data and our own empiri- cal findings indicate that the chemical inhibitor, the antibody, and the siRNA for FGFR1 each selectively tar- get ...
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Human Epidermal Growth Factor Receptor 2 (
... of human epidermal growth factor receptor 2 or HER2/neu with the development of salivary gland carcinomas and use of Herceptin in the treatment of these ...
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Placental Growth Factor and Vascular Endothelial Growth Factor Receptor-2 in Human Lung Development
... The development of BPD has been suggested to result from disruption of vascular development, which leads to an arrest of lung alveolarization. 11,12 Preterm infants who develop BPD have lower levels of VEGF-A than do ...
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Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1.
... We reported previously that CMV infection of fibroblasts induces a basic fibroblast growth factor-like factor (2) which can stimulate endothelial cell proliferation, thus supporting the [r] ...
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Expression of transforming growth factor beta 1 is increased in human vascular restenosis lesions
... https://doi.org/10.1172/JCI116027. Human atheromata obtained in vivo were used to test the hypothesis that transforming growth factor-beta 1 plays a role in the development of vascular ...of ...
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Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases.
... ≤ 1 cm) in X-ray exposure, the presence of soft tissue lesion in the apical area during the operation, and the presence of lesion tissues with granulation tissue mass accompanied by capillary proliferation and ...
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Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction
... Introduction The blood flow through the uterine arteries increases signif- icantly during a physiological pregnancy. In the first trimes- ter it is at 50–90 mL/min, while at the end of the gestation reaches 600–700 ...
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Human capital as a key factor of economic growth in crisis
... Key Factor of Economic Growth in Crisis ...of human capital in overcoming of crisis phenomena in economy by the example of modern ...systems, factor analysis, analysis of causal connections, ...
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Serum reference value of two potential doping candidates—myostatin and insulin-like growth factor-I in the healthy young male
... the growth of both muscle and ...found myostatin was negatively related to BMI, fat mass per- centage, and waist girth after adjustment for ...that myostatin transgenic mice had immature adipogenesis ...
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Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha
... transforming growth factor ...epidermal growth factor (EGF) receptor is activated by both EGF and transforming growth factor-alpha ...normal human pancreas, and that all ...
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Regulation of skeletal muscle growth and gene expression by insulin-like growth factors and myostatin
... endogenous growth factor signaling cascades and their interactions can lead to development of these new ...principal growth factor families that govern both pre-natal and postnatal ...
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Distinct Role of Transforming Growth Factor-Beta 1 and Fibroblast Growth Factors in Human Amelobastoma Epithelial Cell Proliferation
... the growth rate of dental epithelial progenitor cells derived from rat cervical loop, where enamel epithelium is maintained for the continuous growth of rodent incisors, was increased in the presence of ...
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Growth stimulation by coexpression of transforming growth factor alpha and epidermal growth factor receptor in normal and adenomatous human colon epithelium
... epidermal growth factor receptor (EGF-R), by coexpression of transforming growth factor-alpha (TGF-alpha), causes malignant transformation of some fibroblast cell ...abnormal growth ...
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Soluble expression of human insulin like growth factor 1 with the assistance of SUMO fusion partner
... Acknowledgments This work was financially supported by a grant from the National Natural Science Foundation of China (no. 8107071 4) and Zhejiang Province scientific and technological innovations group (no. 2012 ...
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