array comparative genomic hybridization (aCGH)
Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large b-cell lymphoma: a review of the literature
... resolution array comparative genomic hybridization (aCGH) have revealed recurrent copy number alterations (CNA), as well as prognostic indicators in a number of DLBCL subtypes [22-27], for ...
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Array Comparative Genomic Hybridization as a Diagnostic Tool in Cancer
... Array comparative genomic hybridization (aCGH) is a specific molecular cy- togenetic method that combines CGH and DNA microarrays and enables whole molecular cytogenetic ...blinded ...
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Array comparative genomic hybridization of 18 pancreatic ductal adenocarcinomas and their autologous metastases
... Before array CGH was performed, DNA was RNase (RNase, DNase free, Roche, USA) treated and purified a second time before labeling using Kreatech’s (Kreatech Diagnostics, Amsterdam, Netherlands) non-enzymatic ...
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Well differentiated angiosarcoma of spleen: a teaching case mimicking hemagioma and cytogenetic analysis with array comparative genomic hybridization
... aCGH: array comparative genome hybridization; CT: computed tomography; AST: aspartate aminotransferase; DAVID: database for annotation, visualization and integrated discovery; LOH: loss of ...
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Establishment of a new human osteosarcoma cell line, UTOS-1: cytogenetic characterization by array comparative genomic hybridization
... [16]. Genomic DNA was isolated from tumor samples using standard procedures including pro- teinase K digestion and phenol-chloroform ...extraction. Array CGH was performed using the GenoSensor Array ...
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Chromosomal Aberrations in ETV6/RUNX1-positive Childhood Acute Lymphoblastic Leukemia using 244K Oligonucleotide Array Comparative Genomic Hybridization
... the array-CGH data, a total of 155 genomic aberrations (36 gains, 119 losses, excluding copy number polymorphisms) were identified in all eleven patients, in- cluding a patient ...
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Prenatal diagnosis of a de novo interstitial deletion of 11q (11q22.3 → q23.3) associated with abnormal ultrasound findings by array comparative genomic hybridization
... resolution. Array CGH using Agi- lent’s 8 × 60 K commercial arrays (Agilent Technologies, Santa Clara, CA, USA) was performed on DNA ex- tracted from uncultured cord blood and a ...
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A 18p11.23-p11.31 microduplication in a boy with psychomotor delay, cerebellar vermis hypoplasia, chorioretinal coloboma, deafness and GH deficiency
... through array comparative genomic hybridization (aCGH), not overlapping with the previously described one, encompassing three genes, namely ARHGAP28 , LINC00668 and LAMA1 in a 10 year-old boy ...
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Implementation of a genomic medicine multi-disciplinary team approach for rare disease in the clinical setting: a prospective exome sequencing case series
... involved array comparative genomic hybridization (aCGH) testing (pre- dominantly cases involving learning difficulties and neurological phenotypes) and single gene(s) sequencing (in 53% and ...
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Preimplantation genetic diagnosis guided by single-cell genomics
... microarray comparative genomic hybridization and analysis, SNP-array analysis or massively parallel sequence ...aCGH, array comparative genomic hybridization; BAF, ...
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Molecular cytogenetic characterization of undifferentiated embryonal sarcoma of the liver: a case report and literature review
... our array comparative genomic hybridization (aCGH), fluorescence in situ hybridization (FISH) findings, and a missense mutation of TP53 gene by DNA sequencing in a 19-year-old patient ...
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Yield of comparative genomic hybridization microarray in pediatric neurology practice
... Array comparative genomic hybridization (aCGH) is a ge- netic technology used to identify copy number variants (CNVs). A CNV is a duplicated or deleted segment of DNA, greater than 1 kb in ...
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Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers
... 1 Genomic aberrations in cancer. Three classes of genomic aberration that develop in cancer cells are depicted: mutations of less than 1 Kbp in length (top box), structural copy number aberrations (CNAs) ...
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Application of next-generation sequencing for 24-chromosome aneuploidy screening of human preimplantation embryos
... ing array comparative genomic hybridization (aCGH) [15], single-nucleotide polymorphism microarrays (SNP) [16], and quantitative polymerase chain reaction (Q-PCR) ...[17]. Array CGH was ...
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Array-CGH characterization and genotype-phenotype analysis in a patient with a ring chromosome 6
... Array-Comparative Genomic Hybridization (Array-CGH) The array-Comparative Genomic Hybridization (aCGH) study was performed using the Agilent Human Genome CGH ...
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Prenatal diagnosis of 1p34.3 interstitial microdeletion by aCGH in a fetus with jaw bone abnormalities
... Case presentation: The present case involved a female fetus with an interstitial deletion on 1p, presenting with micrognathia in the 2nd trimester routine ultrasound examination. Array-based comparative ...
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13q mosaic deletion including RB1 associated to mild phenotype and no cancer outcome – case report and review of the literature
... hands). Array Comparative Genomic Hybridization on blood identified a mosaic ...Situ Hybridization (iFISH) on both blood genomic DNA and cultured/uncultured blood lymphocytes, ...
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Prenatal diagnosis of Wolf-Hirschhorn syndrome confirmed by comparative genomic hybridization array: report of two cases and review of the literature
... as array comparative genomic hybridization (a-CGH) increased the detection rate of submicroscopic chromo- somal aberrations that could also lead to a WHS pheno- ...
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Application of Array Based Comparative Genomic Hybridization to Pediatric Neurologic Diseases
... Purpose: Array comparative genomic hybridization (array-CGH) is a technique used to analyze quantitative increase or decrease of chromosomes by competitive DNA hybridization of ...
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Genetic analysis of products of conception using a HLPA/SNP-array strategy
... cludes array-based comparative genomic hybridization (aCGH) and single nucleotide polymorphism array (SNP- array) , and it is considered to be the fist-tier testing for detection ...
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