Articular cartilage tissue engineering
Articular cartilage tissue engineering with plasma rich in growth factors and stem cells with nano scaffolds
... the cartilage defect, thus resulting in a lasting defect that decreases tissue function and can serve as a starting point for tissue ...of articular cartilage, past the calcified zone, ...
12
Principles of cartilage tissue engineering in TMJ reconstruction
... As articular cartilage has, in contrast to bone, only a lim- ited capacity to regenerate itself, regeneration supporting therapies are of high relevance when this tissue is involved in the ...
7
Original Article Comparison of the properties of a native articular cartilage extracellular matrix-derived oriented scaffold and the chondro-gide bilayered scaffold-cartilage tissue engineering
... metabolism, and the number of functioning mitochondria increases during cell proliferation and active metabolism, decreases during decay, and reaches zero after cell death. In cases of abundant cell growth, when the cell ...
12
Strain distribution of repaired articular cartilage defects by tissue engineering under compression loading
... of articular cartilage has been predicted theoretically and ana- lyzed experimentally in in vitro systems, few reports focus on what the mechanical condition is after repairing cartilage defects by ...
8
3D Bioprinting for Cartilage and Osteochondral Tissue Engineering
... the articular surfaces within the knee and the tissue engineered replacements were fixed within the ...bone tissue formation and host integration. However the repair tissue was mainly ...
65
Fabrication and in vitro evaluation of an articular cartilage extracellular matrix-hydroxyapatite bilayered scaffold with low permeability for interface tissue engineering
... The cartilage slices were shattered and decellularised under aseptic conditions then smashed in PBS buffer containing ...of cartilage fragments was then centrifuged (500 × ...
18
Fiber Reinforced Cartilage ECM Functionalized Bioinks for Functional Cartilage Tissue Engineering
... bioink containing MSCs) and mechanical (PCL framework) components. To address these objectives, alginate was first functionalized with two different concentrations (0.2% and 0.4% (w/v)) of cECM and the rheology and ...
29
Extracellular matrix production in vitro in cartilage tissue engineering
... hyaline-like cartilage matrix ...for cartilage tissue ...the cartilage matrix than common dynamic culture using spinner flasks ...human articular chondrocytes within alginate beads only ...
9
Tissue engineering: chondrocytes and cartilage
... of articular cartilage depend on the structure and organization of the macromolecules in the ...in cartilage, to produce a tissue that is not only strong in tension but also resistant to ...
6
Piezoelectric smart biomaterials for bone and cartilage tissue engineering
... skin, cartilage and tendon ...and articular cartilage very efficiently ...cell-induced tissue re- pair ...and cartilage tissue engineering are gaining more import- ...for ...
11
Engineering tissues with a zonal structure and composition mimicking native articular cartilage
... Partially confining the gels was predicted to lower the oxygen tension in the bottom of both 2 mm and 4 mm gels, steepening the oxygen gradient as well as reducing glucose availability throughout th e gels (Fig. 4.4). ...
184
Tissue Engineering of Cartilage; Can Cannabinoids Help?
... and cartilage explant cultures has been investigated ...in cartilage breakdown, thereby forming a basis for the identification of novel potential anti-arthritic ...bovine articular chondrocytes ...
16
Gene Delivery of TGF ?3 and BMP2 in an MSC Laden Alginate Hydrogel for Articular Cartilage and Endochondral Bone Tissue Engineering
... either articular cartilage or endochondral bone tissue ...either cartilage or down an osteogenic/endochondral pathway depending on whether TGF-β3 and BMP2 were delivered in combination or in ...
24
Cartilage Tissue Engineering
... of tissue engineering holds great promises for the generation of functional tissue substitutes, by constructing tissue in vitro and implanting it in-vivo ...calf articular chondrocytes ...
10
<p>A novel, self-assembled artificial cartilage–hydroxyapatite conjugate for combined articular cartilage and subchondral bone repair: histopathological analysis of cartilage tissue engineering in rat knee joints</p>
... biphasic cartilage and bone-like scaffolds combined with HAP, for cartilage tissue engineering, which have been developed through self-assembly of cartilage component molecules (HA, AG ...
16
Regeneration of osteochondral defects using developmentally inspired cartilaginous templates
... future tissue engineering strategies targeting larger and hence more challenging chondral, osteochondral defects or whole joint resurfacing ...native tissue prior to implantation, or the oxygen ...
32
Basic science of osteoarthritis
... the articular chondrocyte through diffusion via ...altered articular chondrocyte behavior and in the development of OA (van der Kraan et ...OA cartilage (Dumond et ...
18
EVALUATION OF INHOMOGENEITIES IN HISTOLOGICAL STRUCTURES (CARTILAGE, RETINA)
... human articular cartilage and human retina considered in view of changes during the ageing ...The articular cartilage is characterized by continuous changes of both functions, the cell ...
6
Kappa opioid receptor signaling protects cartilage tissue against posttraumatic degeneration
... It is well established that KOR activation exerts antiin- flammatory effects by reducing production of interleukins in many cells types, such as cardiomyocytes (38), mono- cytes (39), and alveolar osteoclasts (40). KOR ...
13
Novel nano-rough polymers for cartilage tissue engineering
... studies have turned to harsh chemicals to create nanoscale surface features such as strong acids (HNO 3 and HCl), strong bases (NaOH), salt doping (NaCl) followed by aqueous soni- cation, freeze drying, and various ...
9