asymmetric division
A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly
... cell division or to allow the completion of the differentiation into the metacyclic ...‘epi-trypo’ division, the fate of the epimastigote progeny remains to be ...the asymmetric division, a ...
9
Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning
... A balance between stem cell self-renewal and differentiation is vital for tissue homeostasis. Disruption of this balance can lead to tumorigenesis/tissue hyperplasia (owing to an excess of stem cell self-renewal) or ...
7
Hermann, Andrea (2010): Analysis of asymmetric division of hematopoietic stem cells by continuous single cell observation. Dissertation, LMU München: Fakultät für Biologie
... assess asymmetric fate potential of individual HSC we used two different readouts, generation time of daughter cells as well as loss of reconstitution potential as assessed by a live ...the asymmetric fate ...
196
Ephrin Eph signalling drives the asymmetric division of notochord/neural precursors in Ciona embryos
... During animal development, ephrin-Eph signals are well-known for their ability to control cell behaviours such as attraction/ repulsion, adhesion/de-adhesion and migration in a range of developmental contexts (Poliakov ...
7
Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells
... through asymmetric division, in which one daughter cell retains the self-renewal ability, and the other is destined to ...of asymmetric division in normal stem cells (NSCs) and, to a limited ...
6
Wei, Hai (2019): pig-1 MELK and ced-3 Caspase cooperate to control cell polarity in the C. elegans NSM neuroblast. Dissertation, LMU München: Fakultät für Biologie
... mined. In C. elegans, the positioning of the cleavage plane is best understood in the one-cell embryo, which, like QL.p, divides asymmetrically by size and fate (Rose and Gonczy 2014; Wu and Griffin 2017). In general, the ...
112
Uncovering the link between malfunctions in Drosophila neuroblast asymmetric cell division and tumorigenesis
... the asymmetric division machinery func- tion without ...proper asymmetric localization of Miranda in particular, as well as its cargo proteins ...proper asymmetric localization of this protein ...
12
Skin Stem Cell Hypotheses and Long Term Clone Survival - Explored Using Agent-based Modelling
... the asymmetric division scenario (1), all of the 38 lineages remained at the end of three ...(assuming asymmetric division), in contrast to results reported in recent genetic labelling ...
9
Extracellular control of PAR protein localization during asymmetric cell division in the C elegans embryo
... the asymmetric division of ...its asymmetric cell ...of asymmetric cell division is oriented by a cue from the remnant of the previous cell division, called the bud ...cell ...
9
Spatial perturbation with synthetic protein scaffold reveals robustness of asymmetric cell division
... the division of stem cells or stem-like ...the asymmetric division of Caulobacter is robust to spatial variations of cell fate ...cell asymmetric divi- sion in various systems [1-3], so it is ...
10
Brain tumor specifies intermediate progenitor cell identity by attenuating β catenin/Armadillo activity
... the scaffolding protein Axin, and the tumor suppressor Adenomatous polyposis coli (Apc) (Aoki and Taketo, 2007; MacDonald et al., 2009; Niehrs, 2012). This destruction complex phosphorylates β-catenin/Armadillo (Arm) and ...
12
Mechanisms of stomatal development: an evolutionary view
... cell division that is specifically oriented toward the ...by asymmetric division within the stomatal lineage), neigh- boring subsidiary mother cells (SMCs) divide asymmetric- ally to produce ...
9
Specification of basal region identity after asymmetric zygotic division requires mitogen activated protein kinase 6 in rice
... cell division is a key step in cellular differentiation in multicellular ...plants, asymmetric zygotic division produces the apical and basal ...in asymmetric divisions such as zygotic ...
8
Components of the transcriptional Mediator complex are required for asymmetric cell division in C elegans
... the asymmetric division of certain blast cells, including the T blast cell, is regulated by lin-17/frizzled and lin-44/wnt (Herman et ...the division is disrupted, resulting in symmetric ...
9
Caenorhabditis elegans ced-3 Caspase Is Required for Asymmetric Divisions That Generate Cells Programmed To Die
... on the two conserved C. elegans engulfment pathways (Chakraborty et al. 2015). We found that at QL.p metaphase, the amount of TAC-1 associated with the anterior centrosome is 1.25-fold greater than that associated with ...
16
Conservation and divergence of YODA MAPKKK function in regulation of grass epidermal patterning
... species, asymmetric cell divisions produce one daughter cell that acts as a stomatal precursor and another that differentiates as an epidermal pavement cell (Fryns- Claessens and Van Cotthem, 1973; Dong and ...
9
klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division
... during asymmetric division, proper specification of sibling cell identity requires precise control of stem cell ...during asymmetric stem cell division is likely to advance our knowledge in ...
11
Repair rather than segregation of damage is the optimal unicellular aging strategy
... included, asymmetric division was beneficial at higher damage accumulation rates in the absence of repair and damage being toxic, in agreement with [32] (Additional files ...lets division be ...
21
WNTers in La Jolla
... Wnt-directed asymmetric cell ...Wnt-dependent asymmetric cortical and nuclear localizations of crucial signaling components direct polarized cell divisions and subsequent fate determination of each daughter ...
7
Asymmetric B Cell Division in the Germinal Center Reaction
... allows asymmetric cell division(Barnett et ...which asymmetric division occurs, and the potential functional role of asymmetric ...
110