AT motif binding factor 1 (ATBF1)
Quach_unc_0153D_17395.pdf
... SP1 motif sites exceeded that expected under a multinomial model of DNaseI digestion signal ...stratified motif sites into active and inactive based on presence of corresponding ChIP-seq signal for the ...
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Genome-wide identification of grain filling genes regulated by the OsSMF1 transcription factor in rice
... the binding motifs of OsSMF1, which is a basic leucine zipper transcription factor involved in the regulation of rice seed ...their 1-kb promoter regions, ...(GCN4 motif), patatin-like gene ...
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A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation
... alpha motif and HD domain-containing protein 1 (SAMHD1) regu- lates intracellular deoxynucleoside triphosphate (dNTP) levels and functions as a retrovi- ral restriction factor through its dNTP ...
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A Motif Co-Occurrence Approach for Genome-Wide Prediction of Transcription-Factor-Binding Sites in Escherichia coli
... true binding sites co-occur with a second binding site, either for the same transcription factor or a different ...transcription factor that regulates a particular ORF often has multiple ...
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Proteomics approaches for the studies of bone metabolism
... tripartite motif-containing 16, ATF4: activating transcription factor 4, MECP2: methyl CpG binding protein 2, THRAP3: thyroid hormone re- ceptor-associated protein 3, PTRF: polymerase I and ...
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MCOIN: a novel heuristic for determining transcription factor binding site motif width
... (Figure 1). Clearly, biologists are interested in the true motif width; however, while some motifs provide statistically strong signals, the majority of motifs are more subtle and in the worst cases may be ...
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Soluble Thy-1 reverses lung fibrosis via its integrin-binding motif
... growth factor receptors (24), and display altered cytokine signaling (25), showing enhanced myofibroblastic differentiation (26), apoptosis resistance (27), and enhanced activation of latent TGF-β (22, ...
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Evaluation of RNA binding motif protein 3 expression in urothelial carcinoma of the bladder: an immunohistochemical study
... The literature concerning the exact role of RBM3 in carcinogenesis has so far been conflicting. RBM3 is a hypothermia-induced protein [3, 8–10] that has been found to assist in mRNA stability [12] and to increase ...
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Lysine 63-Linked TANK-Binding Kinase 1 Ubiquitination by Mindbomb E3 Ubiquitin Protein Ligase 2 Is Mediated by the Mitochondrial Antiviral Signaling Protein
... regulatory factor 3 (IRF3) and IRF7 (IRF3/7), which synergisti- cally bind to the IFN-  gene promoter to induce its ...DLAIS motif at amino acid po- sitions 438 to 442 of MAVS that is indispensable for ...
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Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis
... adenine triphosphates (dNTPs) spiked out with deoxyuridine triphosphate (dUTP) were then used to reverse transcribe the cRNA into single-stranded sense strand cDNA. The cDNA was then fragmented with uracil DNA ...
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Selective Inhibition of the Human tie-1 Promoter with Triplex-Forming Oligonucleotides Targeted to Ets Binding Sites
... transcription factor binding motifs (designated E-1 and E-2) in the human tie-1 ...The binding of antiparallel and parallel (control) purine motif oligonucleotides (21-22 bp) ...
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Regulation of sex hormone binding globulin and insulin-like growth factor binding protein-1
... ovary syndrome and were anovulatory. They presented with oligomenorrhoea or secondary amenorrhoea. Seven of the women were hirsute (Ferriman-Gallwey score >7). The diagnosis was confirmed by an ultrasound scan, a ...
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The ESCRT-Associated Protein Alix Recruits the Ubiquitin Ligase Nedd4-1 To Facilitate HIV-1 Release through the LYPXnL L Domain Motif
... (lane 1) or with HA-Alix (lane ...(lanes 1, 3, and 5) or with Flag-Alix alone (lanes 2, 4, and ...lanes 1 and 2), HA-ubiquitin (lanes 3 and 4), or cellular ubiquitin molecules conjugated to Flag-Alix ...
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A Diacidic Motif in Human Immunodeficiency Virus Type 1 Nef Is a Novel Determinant of Binding to AP-2
... AP-2 binding (6, 8, 11, 12, 17, ...dileucine motif but extends to most residues within the loop ...for binding to AP-2 subunits by using aY3H assay (vectors are shown in ...dileucine motif ...
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Thermodynamic and Structural Characterization of the Interaction between Wd40 Repeat Containing Protein 5 (Wdr5) and Human Set1 Family Methyltransferases
... Win motif peptides to inhibit the H3K4 dimethylation activity of the MLL1 core ...Win motif peptides are ...Win motif peptides bearing single amino acid substitutions are synthesized and their ...
276
Characterization and Protective Property of Brucella abortus cydC and looP Mutants
... The differences in survival exhibited by the IVKB9007 looP:: Tn5 and cydC::Tn5 mutants might prove to be potential advan- tages for vaccine strains. It is possible that the rapid clearance of the IVKB9007 cydC::Tn5 ...
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Uterine receptivity and implantation: The regulation and action of insulin-like growth factor binding protein-1 (IGFBP-1), HOXA10 and forkhead transcription factor-1 (FOXO-1) in the baboon endometrium
... In primates, the phase of the menstrual cycle when the uterus becomes receptive is initially dependent on estrogen and progesterone. Further morphological and biochemical changes are induced as a result of biochemical ...
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The basal transcription machinery as a target for cancer therapy
... growth factor (TGF- βR2) [112]; the activation of TGF-βR2 appears to be a unique function of the MED-12 subunit because other subunits of mediator do not localize outside of the nucleus, suggesting a ...
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Systemic administration of mesenchymal stem cells combined with parathyroid hormone therapy synergistically regenerates multiple rib fractures
... Fig. 1 Rib defect surgery and timeline. After the rat had been anesthetized, intubation and mechanical ventilation were established to maintain positive pleural pressure. The animal was then placed on its side and ...
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Functions of Rhotekin, an Effector of Rho GTPase, and its Binding Partners in Mammals
... a binding partner for small GTPase Rho by yeast two- hybrid analysis using a mouse embryo cDNA library ...class 1 PDZ-binding motif (Figure ...
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