Atherogenic diet
Effect of Andrographolide on Monocyte Chemoattractant Protein-1 Expression at the Initiation Stage of Atherosclerosis in Atherogenic Diet-Fed Rats
... standard diet, (B) Group 2 (atherogenic control) was given an atherogenic diet, (C) Group 3 (treated group) was given an atherogenic diet and treated with andrographolide 40 ...
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Original Article Cardioprotective effect of resveratrol on atherogenic diet-fed rats
... standard diet, ad libitum. To study influence of resvera- trol in standard diet-fed conditions, a (Res, n = 6) group received standard diet and 6 mg/l res- veratrol (trans-3, 40, ...
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NOVEL BIOMARKERS OF ATHEROGENIC DIET INDUCED DYSLIPIDEMIA AND METABOLIC SYNDROME SUPPRESSED BY TERMINALIA ARJUNA
... ABSTRACT: Atherosclerosis results from the slow deposition of fatty materials in media and large arteries leading to mortality worldwide. Terminalia arjuna is an herb of Combretaceae family which contains flavonoids, ...
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Catechins green tea upregulates the expression of ABCA1, ABCG1, and SRB1 in rats induced atherogenic diet
... ABCA1 mRNA induced by the activation of LXR signaling through PPARγ–LXR–ABCA1 signaling pathway. LXRα is the target PPARγ, upregulation ApoE, and transporter ABCA1 and ABCG1. PPARγ ligands can activate PPARγ which have ...
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Antiobesity activity of ethanolic extract of fruits of Terminalia bellirica on atherogenic diet induced obesity in experimental rats
... Obesity is a common metabolic disorder and rapidly becoming a global public health problem in the 21 st century. Millions of adults are diagnosed as obese each year. Therefore, the present study was designed to ...
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BLOOD CHOLESTEROL LOWERING EFFECT OF ADENANTHERA PAVONINA SEED EXTRACT ON ATHEROGENIC DIET INDUCED HYPERLIPIDEMIA RATS
... water, groups B rats served as positive control and received atherogenic diet and C animals were administered with 200 mg/kg doses of the methanol extract. The extract was administered to the rats per once ...
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ANTI-OBESITY AND HYPOLIPIDEMIC ACTIVITY OF METHANOL EXTRACT OF TABERNAEMONTANA DIVARICATA ON ATHEROGENIC DIET INDUCED OBESITY IN RATS
... Table 1 shows the changes in the body weight in the different group of animals, during the experiment. Consumption of Atherogenic diet (AD) for six weeks produced a significant (p< 0.001) increase in ...
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Genetic control of inflammatory gene induction and NF kappa B like transcription factor activation in response to an atherogenic diet in mice
... the atherogenic diet the susceptible C57BL/6 mice exhibited significant NF-kappa B-like activation whereas the resistant C3H/HeJ mice exhibited little or no ...
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Atherogenic diet increases cholesteryl ester transfer protein messenger RNA levels in rabbit liver
... cholesterol diet. Thus, in response to the atherogenic diet there is an early increase in liver CETP mRNA, probably causing increased CETP synthesis and secretion, and increased plasma ...by ...
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Aspirin inhibits development of coronary atherosclerosis in cynomolgus monkeys (Macaca fascicularis) fed an atherogenic diet
... of diet-induced atherogenesis in cynomolgus monkeys was studied. The diet consisted of 2% cholesterol and 10% butter by weight for 24 ...the atherogenic diet and five monkeys received the ...
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ANTI-HYPERLIPIDEMIC ACTIVITY OF LEAVES OF Sphaeranthus indicus ON ATHEROGENIC DIET INDUCED HYPERLIPIDEMIC IN RATS
... and Atherogenic index, and Total cholesterol level in liver were ...with atherogenic diet revealed a statistically significant increase in serum level of total cholesterol, triglycerides, LDL, VLDL ...
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Studies on the Structure of Low Density Lipoproteins Isolated from Macaca Fascicularis Fed an Atherogenic Diet
... experimental diet, the peak temperature of the cholesterol-ester transition (42-48°C) was above body temperature (39°C), but below body temperature on the control diet ...
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Immune deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet
... Inbred strain C57BL/6J mice develop typical atherosclerotic fatty streaks in the aorta after 15 wk on a high fat, high cholesterol diet. To investigate the effects of the immune system on the development of fatty ...
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Original Article Genistein alleviates atherosclerosis in apolipoprotein E-deficient mice by interrupting the OX40/OX40L pathway
... T-cells [26]. Then these interactions may lead to enhanced inflammatory responses in athero- sclerotic plaques. Although genistein has been shown to have anti-inflammatory effects, its effects on OX40 and OX40L ...
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Regulation of intestinal and hepatic apoprotein synthesis after chronic fat and cholesterol feeding
... contrast, hepatic apo E mRNA concentration and synthesis were increased after the atherogenic diet, consistent with pretranslational regulation. The response to cholesterol feeding for hepatic apo AI and E ...
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Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo
... genic diet compared with the control mice, but this difference was not detected at any other time point dur- ing the study, making it unlikely that this was an effect of macrophage LPL ...the atherogenic ...
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Diet induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption
... an atherogenic diet for 12 wk, and extensive deposition of lipid-filled macrophages was found outside the cardiovascular ...the atherogenic diet for 12 wk, the amount of apo E in their total ...
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The combined role of P and E selectins in atherosclerosis
... on atherogenic diet, the LDLR 2 / 2 P/E 2 / 2 mice developed fatty streaks in the aortic sinus that were five times smaller than those in LDLR 2 / 2 P/E 1 / 1 ...the diet, the lesions spread ...
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Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice
... After 15 wk of consumption of the atherogenic diet, the parental C57BL/6J and C3H/HeJ strains and BXH recombinant inbred strains were assessed for aortic lesion formation by standard his[r] ...
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Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
... dismutase activity. Treatment with atorvastatin limited LDL oxidation significantly (LDL thio- barbituric acid reactive substances 2.19 nmol/mg protein, LDL-conjugated diene 222 µmol/mg protein). Paraoxonase, which ...
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