atherosclerotic plaque in vitro
Reactive oxygen species produced by macrophage derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro Implications for atherosclerotic plaque stability
... of atherosclerotic plaques often contain lipid-laden macrophages and display matrix metallopro- teinase ...in vitro using metalloproteinases secreted by cultured human vascular smooth muscle ...
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CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis
... advanced atherosclerotic lesions (9, 10, ...M-CaMKII–KO atherosclerotic lesions for MerTK expression by immunofluorescence microscopy and found that M-CaMKII–KO lesions expressed significantly more of the ...
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Shear stress–induced changes in atherosclerotic plaque composition are modulated by chemokines
... of plaque growth might have increased shear stress locally, and this increase in shear stress might have provided the trigger for fractalkine ...advanced atherosclerotic lesions. Recent in vitro ...
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Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
... expression and enzyme activity following upregulation of catalase mRNA, with no significant alteration in mRNA expression of superoxide dismutase in vascular smooth muscle cells in vitro. In the same study, while ...
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Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE−/− mice
... in vitro and clinical studies have shown that BBR has anti-inflammatory effects, we have not explored whether BBR reduces atherosclerosis in animal ...duce plaque size, but also improve plaque ...
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High resolution intravascular magnetic resonance quantification of atherosclerotic plaque at 3T
... identify atherosclerotic lesions without X-ray fluoroscopic guidance, and provide high-resolution (< 100 μm) imaging of vessel anatomy and accurate FCT and wall thickness measurements in a con- ventional ...
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Statins Induce the Accumulation of Regulatory T Cells in Atherosclerotic Plaque
... hicle (control). Simvastatin significantly increased the number of Tregs and the expression of Treg marker Foxp3 (Forkhead/winged helix transcription factor), transforming growth factor (TGF)-β and interleukin (IL)-10 in ...
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Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis
... lesions of the aortic roots, which might also be explained by the advanced, cell-depleted fibrous plaques of older mice. One cannot exclude that apoptosis might be affected in early or intermediate atherosclerotic ...
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Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque
... face plaque area, more unstable plaque with heavier accumulation of lipids, more macrophages, less smooth muscle cells and collagen, which were associated with aggravated ...in atherosclerotic ...
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Simulation of human atherosclerotic femoral plaque tissue: the influence of plaque material model on numerical results
... in vitro experimental data obtained through the mechanical testing of healthy and ather- osclerotic arterial ...human atherosclerotic plaque tissue, a recent trend has emerged in current literature ...
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Carotid Atherosclerotic Plaque Progression and Change in Plaque Composition Over Time: A 5 Year Follow Up Study Using Serial CT Angiography
... investigate atherosclerotic carotid plaque progression in hu- ...quantify atherosclerotic plaque measures in vivo and track changes over time in large study ...in plaque volume was ...
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3D Quantitative Evaluation of Atherosclerotic Plaque Based on Rotational Angiography
... ticular, atherosclerotic plaque has been associated with many acute clinical ...icant atherosclerotic narrowing at the origin of the internal carotid ...
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<p>Berberine Attenuates Arterial Plaque Formation in Atherosclerotic Rats with Damp-Heat Syndrome via Regulating Autophagy</p>
... According to epidemiological data, the mortality rate of AS-related vascular diseases in individuals aged older than 35 years has decreased from 16% in 1980 to 4% in 2010; 1 however, the incidence of AS in China remains ...
12
In silico analyses of metagenomes from human atherosclerotic plaque samples
... used atherosclerotic tissue samples from a group of 15 patients that underwent elective carotid endarterectomy following repeated transient is- chemic attacks or minor strokes (samples from symp- tomatic ...
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Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR −/− mouse model of atherosclerosis
... these atherosclerotic plaques can lead to ischaemic injury by a number of mechanisms such as complete occlusion of the blood vessel or, alternatively, the plaque may become unstable and rupture resulting in ...
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Sex Differences of High Risk Carotid Atherosclerotic Plaque with Less Than 50% Stenosis in Asymptomatic Patients: An In Vivo 3T MRI Study
... carotid plaque morphology, including thin/ruptured fibrous cap, IPH, type VI plaque, and large LR/NC plaque across the entire spectrum of carotid disease as measured by carotid ...
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Cholesterol in human atherosclerotic plaque is a marker for underlying disease state and plaque vulnerability
... of plaque vulnerability in diabetic patients, including increased lipid and macrophage content and decreased collagen ...peripheral plaque samples from 14 dia- betic and 16 non-diabetic ...
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Identification and Quantitative Assessment of Different Components of Intracranial Atherosclerotic Plaque by Ex Vivo 3T High Resolution Multicontrast MRI
... Intracranial atherosclerosis is increasingly recognized as an important cause of stroke worldwide. As with carotid atheroscle- rosis, there is increasing recognition that aggressive (dual) antiplatelet therapy may be ...
7
Carotid Plaque Morphology and Ischemic Vascular Brain Disease on MRI
... (ie, plaque size, the presence of intraplaque hemor- rhage, or lipid core) in 80 carotid arteries to be not independently predictive of the severity of WMLs, refuting the large-vessel dis- ease and unstable ...
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Bitter melon (Momordica charantia) attenuates atherosclerosis in apo-E knock-out mice possibly through reducing triglyceride and anti-inflammation
... of atherosclerotic pla- ques containing vascular smooth muscle cells, macro- phages and collagen fibers were analyzed by immunohistochemistry and Masson’s trichrome stain- ing ...
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