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ATP binding cassette

Atovaquone and quinine anti malarials inhibit ATP binding cassette transporter activity

Atovaquone and quinine anti malarials inhibit ATP binding cassette transporter activity

... excretion. ATP binding cassette (ABC) transport proteins are particularly involved in drug deposition, as they are located at membranes of many uptake and excretory organs and at protective barriers, ...

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Contributions of Aspergillus fumigatus ATP-Binding Cassette Transporter Proteins to Drug Resistance and Virulence

Contributions of Aspergillus fumigatus ATP-Binding Cassette Transporter Proteins to Drug Resistance and Virulence

... T he filamentous fungal pathogen Aspergillus fumigatus is the most common cause of invasive mold infection in humans, and it is associated with an alarmingly high mortality rate. Some triazole antifungal drugs ...

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Copy number variations of the ATP binding cassette transporter ABCC6 gene and its pseudogenes

Copy number variations of the ATP binding cassette transporter ABCC6 gene and its pseudogenes

... The ATP-binding cassette transporter ABCC6 belongs to a large family of membrane proteins (ABC transpor- ters) that are a highly conserved and present in all organisms from bacteria to man ...

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A Review on ATP Binding Cassette (ABC) Transporters

A Review on ATP Binding Cassette (ABC) Transporters

... The ATP binding cassette (ABC) proteins represent a highly diversify superfamily in all living kingdoms, with 50 human proteins, 14 of which are associated with various ...

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The impact of ATP-binding cassette transporters on metabolic diseases

The impact of ATP-binding cassette transporters on metabolic diseases

... metabolism. ATP binding cassette (ABC) transporters are one of the largest transport protein superfamilies that exist in nearly all living organisms and are mainly located on lipid-processing ...

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Coexpression of ATP binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

Coexpression of ATP binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

... Mutations in either ATP-binding cassette (ABC) G5 or ABCG8 cause sitosterolemia, an autosomal recessive disorder of sterol trafficking. To determine the site of action of ABCG5 and ABCG8, we ...

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Expression of Multidrug Resistance ATP Binding Cassette (ABC) Transporters in Canine Mammary Tumors

Expression of Multidrug Resistance ATP Binding Cassette (ABC) Transporters in Canine Mammary Tumors

... Mammary neoplasms are the most common tumors in female dogs. They are usually treated using solely surgical mastectomy—which is recognized as unsatisfactory in many cases. Given this, the benefits of chemotherapy in dogs ...

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ATP binding cassette A1 deficiency causes cardiolipin driven mitochondrial dysfunction in podocytes

ATP binding cassette A1 deficiency causes cardiolipin driven mitochondrial dysfunction in podocytes

... decreased ATP-binding cassette A1 (ABCA1) expression in glo- merular tissue obtained from research kidney biopsies of Pima Indians with type 2 diabetes (T2D) ...an ATP-dependent mechanism, ...

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Human ATP-binding cassette (ABC) transporter family

Human ATP-binding cassette (ABC) transporter family

... the ATP-binding cassette (ABC) ...by ATP hydrolysis to move substrates across membranes in or out of cells or into cellular vesicles, against their electrochemical ...

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ATP-binding cassette (ABC) transporters in normal and pathological lung

ATP-binding cassette (ABC) transporters in normal and pathological lung

... (ATP-binding cassette) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy- dependent ...

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The role of ATP-binding cassette transporter A2 in childhood acute lymphoblastic leukemia multidrug resistance

The role of ATP-binding cassette transporter A2 in childhood acute lymphoblastic leukemia multidrug resistance

... the ATP- binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular ...al., Atp-binding cassette transporter ...

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Partial characterization of genes encoding the ATP binding cassette proteins of Cryptosporidium parvum

Partial characterization of genes encoding the ATP binding cassette proteins of Cryptosporidium parvum

... two ABC proteins [the H. sapien ATP- binding cassette A5 (HuABCA5) and T. cruzi ABCA1 transporter (TcABCA1)]. It was 65% similar to HuABCA5_N and 59% similar to TcABCA1_N. However, neither the ...

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The COMATOSE ATP-binding cassette transporter is required for full fertility in Arabidopsis

The COMATOSE ATP-binding cassette transporter is required for full fertility in Arabidopsis

... thiolase (KAT), each of which is encoded by more than one gene in Arabidopsis (Arabidopsis thaliana; for re- view, see Graham and Eastmond, 2002; Baker et al., 2006). Prior to b -oxidation, substrates must be acti- vated ...

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The ATP-binding cassette (ABC) transporter OsABCG3 is essential for pollen development in rice

The ATP-binding cassette (ABC) transporter OsABCG3 is essential for pollen development in rice

... To understand the role of OsABCG3 in tapetum development and pollen development, we compared the expression patterns of a few key genes essential for tapetum degeneration and pollen wall[r] ...

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Pulmonary Nodules in a Newborn With ATP-Binding Cassette Transporter A3 (ABCA3) Mutations

Pulmonary Nodules in a Newborn With ATP-Binding Cassette Transporter A3 (ABCA3) Mutations

... triphosphate–binding cassette transporter A3 (ABCA3) have been reported in infants and children with fatal surfactant deficiency and interstitial lung ...

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The COMATOSE ATP-binding cassette transporter is required for full fertility in arabidopsis

The COMATOSE ATP-binding cassette transporter is required for full fertility in arabidopsis

... GABA metabolism in flowers of cts and kat2-1 mutants Since γ-amino butyric acid GABA is believed to be required for correct pollen tube growth and targeting Palanivelu et al., 2003, we t[r] ...

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An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein

An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein

... Cj0982 is a major immunogenic protein in C. jejuni and a promising vaccine candidate. ApaA, a Cj0982 orthologue, is highly immunogenic in A. pleuropneumoniae, a bacte- rium that causes a highly contagious and often fatal ...

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Modulation of Leishmania ABC Protein Gene Expression through Life Stages and among Drug-Resistant Parasites

Modulation of Leishmania ABC Protein Gene Expression through Life Stages and among Drug-Resistant Parasites

... ATP-binding cassette (ABC) proteins form the largest fam- ily of transmembrane proteins and are found in all living or- ganisms ...the ATP- dependent transport of a variety of molecules across ...

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Quantification of CDR1 Gene Expression in Fluconazole  Resistant Candida Glabrata Strains Using Real-time PCR

Quantification of CDR1 Gene Expression in Fluconazole Resistant Candida Glabrata Strains Using Real-time PCR

... ABC transporters, CgCDR1 and CgPDH1 play dominant roles in fluconazole resistance (13, 14). Azole resistance in C. glabrata was mainly asso- ciated with mutation or overexpression of CDR1 and CDR2 genes,” which encode ...

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RPE phagocytic function declines in age related macular degeneration and is rescued by human umbilical tissue derived cells

RPE phagocytic function declines in age related macular degeneration and is rescued by human umbilical tissue derived cells

... ABCA1: ATP-binding cassette transporter 1; AMD: age-related macular degen- eration; ARHGAP9: Rho GTPase activating protein 9; ATCC : American Type Culture Collection; ATP: adenosine ...

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