ATP-binding cassette proteins
Coexpression of ATP binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface
... either ATP-binding cassette (ABC) G5 or ABCG8 cause sitosterolemia, an autosomal recessive disorder of sterol ...the proteins were transported to the trans-Golgi ...
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Partial characterization of genes encoding the ATP binding cassette proteins of Cryptosporidium parvum
... ABC proteins of the ...these proteins may play a role in metabolic interaction between the parasite and the infected ...both proteins also correlates well and supports a role as drug efflux pumps ...
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ATP-binding cassette (ABC) transporters in normal and pathological lung
... way tissue CFTR can be abnormally expressed in remod- elled or dedifferentiated epithelium [122,123]. whereas in delta F508 CFTR epithelial cells there may be a normally processed CFTR [120,124]. The regulation and ...
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Evaluation of the in vitro expression of ATP binding cassette (ABC) proteins in an Ixodes ricinus cell line exposed to ivermectin
... of ATP-binding cassette (ABC) transporter proteins (P-glycoproteins, PgP) has been implicated in resistance to the acaricide ivermectin in the ticks Rhipicephalus (Boophilus) microplus and ...
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A Review on ATP Binding Cassette (ABC) Transporters
... transporters proteins are capable of transporting a vast and chemically diverse array of compounds, which are structurally unrelatedacross the plasma membrane as well as intracellular ...major proteins ...
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Localization of the ATP binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane
... transport proteins responsible for this type of resistance are so- called multidrug resistance proteins (MDR/MRP), most of which belong to the superfamily of ATP binding cassette (ABC) ...
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"We Are Not Hired Help:" The 1968 Statewide Florida Teacher Strike, the Rise of Modern Conservatism, and the Potency of Teacher Power
... pump proteins belonging to different transporter protein families capable of transporting structurally diverse ...pump proteins belong to four families, which include the resistance-nodulation- division ...
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HIGH DENSITY LIPOPROTEIN: ROLE IN REVERSE CHOLESTEROL TRANSPORT
... various proteins, enzymes and receptors such as ATP-binding cassette transporter class B-1 (ABCA1), endothelial lipase (EL), scavenger receptor class B type I (SR-BI), cholesteryl ester ...
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Contributions of Aspergillus fumigatus ATP-Binding Cassette Transporter Proteins to Drug Resistance and Virulence
... selection cassette was released from the plasmid pSKB57 (provided by Stacey Klutts, University of Iowa) by SpeI/EcoRV cleavage and gel puri- ...disruption cassette, while pSP45 was di- gested with AleI/KpnI ...
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Human ATP-binding cassette (ABC) transporter family
... ABC proteins transport a number of endogenous substrates, including inorganic anions, metal ions, peptides, amino acids, sugars and a large number of hydrophobic compounds and metabolites across the plasma ...
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The impact of ATP-binding cassette transporters on metabolic diseases
... Since people often develop multiple metabolic aliments simultaneously, it is desirable to have a therapy that can target several metabolic diseases at the same time. Con- sidering that one of the roots of metabolic ...
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Studies on the human choroid plexus in vitro
... transport proteins that are important for the CP function, for instance, ATP-binding cassette transporters ABCB1, ABCB4, ABCC1 [8], or to explore developmental changes in CP morphology and ...
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Novel analytical methods to interpret large sequencing data from small sample sizes
... in ATP-binding cassette subfamily B member 1 (ABCB1 also known as multidrug resistance protein 1, MDR1), encoding a major IM membrane efflux trans- porter, have already been identified and associated ...
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Insight into the role of p62 in the cisplatin resistant mechanisms of ovarian cancer
... encoding ATP-binding cassette (ABC) transporters (known as efflux pumps) ABCC2 and ABCF2, which transport molecules across cellular membranes, are also target genes of NRF2 [65, ...ubiquitinated ...
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Molecular chess? Hallmarks of anti cancer drug resistance
... The ATP-binding cassette (ABC) superfamily of proteins includes a number of membrane proteins able to transport a wide diversity of ...
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Lipoproteins, cholesterol homeostasis and cardiac health
... Cholesterol absorption is achieved through pas- sage across brush border membranes and into intes- tinal enterocytes in the jejunum. While details of the mechanism are still unclear, recent studies have iden- tified key ...
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The Anopheles gambiae ABC transporter family: phylogenetic analysis and tissue localisation provide clues on function and role in insecticide resistance
... of ATP-binding cassette (ABC) transporters in conferring insecticide resistance has received much attention ...resistance proteins described in other species are associated with resist- ance ...
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ABC transporter research: going strong 40 years on
... The ATP-binding cassette (ABC) transporter field emerged from studies on nutrient uptake in bacteria in the 1970’s with the biochemical characterization of substrate-binding protein ...
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Modularity analysis based on predicted protein-protein interactions provides new insights into pathogenicity and cellular process of Escherichia coli O157:H7
... secreted proteins [57]. Mod- ule 115 has three proteins, shown in Additional File 10, Figure S1B: the a, b, and g subunits of ...periplasmic proteins, RseA and RseB, together with ...periplasmic ...
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The COMATOSE ATP-binding cassette transporter is required for full fertility in Arabidopsis
... A CTS promoter-ORF cassette was prepared in several stages. A promoter fragment corresponding to 2,638 to 1,445 bp upstream of the ATG was amplified with primers CTS ProFW2 (5#-GAGTACTTGGAAGAAGGCGG- TGA-3#) and ...
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