ATP release
Air-Stimulated ATP Release from Keratinocytes Occurs through Connexin Hemichannels
... Cutaneous ATP release plays an important role in both epidermal stratification and chronic pain, but little is known about ATP release mechanisms in keratinocytes that comprise the ...analyzed ...
10
Endothelial cation channel PIEZO1 controls blood pressure by mediating flow induced ATP release
... endothelial release of ATP is a critical upstream step in the mechanotransducing signaling cascade, resulting in NO formation and vascular relaxation (17, 33, ...The ATP released in response to flow ...
11
Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release
... osteoblasts treated for 14 days with (C) UTP (≤4-fold) and (D) 2-thioUTP (≤3-fold). (E) Acute treatment with UTP (≥10µM) increased ATP release by ≤4-fold for up to 60 minutes. (F,G,H) No effect of UTP ...
37
Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells
... cause ATP release and therefore stimulate purinergic signalling in exocrine pancreatic ...large ATP re- lease from both acinar and duct cells ...lower ATP release [34, 35]. We ...
16
Radiated Ultrashort High Power Electromagnetic Pulses Induce ATP Release in B16F10 Murine Melanoma Cells
... toward ATP. Thus, the so-called extracellular ATP (eATP) might appear as a major physiological event [25] especially in the context of electromagnetic or electric field stimulation [24] ...mechano-sensitive ...
9
Pannexin 1 mediated ATP release from area CA3 drives mGlu5 dependent neuronal oscillations
... 9 measured analyte. Null sensors contain no enzymes and measure only non-specific electroactive signals. Pairs of sensors (ATP and null; adenosine and null) were inserted into the stratum radiatum of the ...
41
Characterization of a multiprotein complex involved in excitation-transcription coupling of skeletal muscle
... extracellular ATP at rest, reinforcing our previous demonstration that Panx1 is the conduit for ATP release in skeletal muscle cells [19, ...20]. ATP release evoked by electrical ...
16
Activity dependent release of Adenosine: a critical re evaluation of mechanism
... detect ATP release following trains of stimuli [60]. Release of ATP by local electroporation ...of ATP broken down to adenosine was relatively small (~20 %) suggesting that complete and ...
30
Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation
... extracellular ATP to <1% of control levels within 2 minutes; continuous exposure to apyrase maintained this inhibition for up to 14 ...endogenous ATP in stimulating cell ...the ATP release ...
13
Cannabinoid receptors contribute to astroglial Ca2+ signalling and control of synaptic plasticity in the neocortex
... The short HFS train caused significant elevation of the frequency of purinergic mEPSCs in the pyramidal neurons of WT mice, this elevation being associated with increased Figure 2. (Overleaf.) Detection of ATP ...
12
Basal Nucleotide Levels, Release, and Metabolism in Normal and Cystic Fibrosis Airways
... and ATP-diphosphohydrolases (ATPDase) activi- ties from other glandular tissues such as ovi- duct (47,48) and prostate ...airway ATP concentration, with a potential consequence being reduced mucocil- iary ...
14
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding
... demonstrated that TRPV4 –/– mice manifest an incontinent phenotype but show normal exploratory activity and anxiety-related behavior. Cystometric experiments revealed that TRPV4 –/– mice exhibit a lower frequency of ...
11
Role of the P2X7 receptor in the osteogenic differentiation of mesenchymal cells and in osteoclast fusion
... of ATP release and P2X7 receptors in mediating the differentiation direction of ...of ATP and P2 receptors in stem cell biology is a fast expanding field with an emerging concept that the P2X7 ...
7
The dual roles of red blood cells in tissue oxygen delivery: oxygen carriers and regulators of local blood flow
... to ATP release (Jensen et ...of ATP release stimulated by deoxygenation in rainbow trout, assuming that the Hb–band 3 interaction and its influence on glycolysis trigger erythrocyte ...
7
The P2X receptor mediated regulation of inhibitory synaptic transmission
... of ATP molecules they are unable to simply diffuse across the plasma membrane (Chaudry, 1982), suggesting more specialised pathways are required for ATP ...of release mechanisms can operate in the ...
164
Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder
... of ATP release [9]. Moreover, in our lab we could evoke ATP release with carbachol in primary smooth muscle cell cul- ture [Unpublished ...the release of ATP for ...
7
Targeting adenosine for cancer immunotherapy
... be broadened and refined. The efficacy of combination regimens with other immune checkpoint inhibitors has been established in preclinical studies and evaluation in clinical studies has begun. Furthermore, upstream/down- ...
9
ATP and ATP receptors in human dental pulp
... mechanical ATP release could be avoided if only one third to one half o f the bathing solution was replaced with new solution without touching the ...in ATP concentration in the ...lytic ATP ...
117
Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response
... of ATP at the two sites are syn- ergistic: ATP in the carotid body initiates the response to hypoxia (increases ventilation), and the later release of ATP in the ventral respiratory column ...
9
Adenosine 5′-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans
... mg ATP as proximal-release pellets, 5000 mg ATP as distal-release pellets, or placebo proximal- release ...mg ATP dissolved in 100 mL water (30 ± 4°C), or water only (placebo), ...
9