Atrial myocytes
Difference of Sodium Currents between Pediatric and Adult Human Atrial Myocytes: Evidence for Developmental Changes of Sodium Channels
... human atrial cardiomyocytes was placed in a 1-mL chamber mounted on the stage of an inverted micro- ...human atrial cells adhered to the bottom of the chamber, the external solution for recording sodium ...
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Temperature dependence of L type Ca(2+) channel current in atrial myocytes from rainbow trout
... ventricular myocytes from rainbow trout (101 ms for fish acclimated to 18 °C and 73 ms for fish acclimated to 4 °C; Vornanen, ...ventricular myocytes (27 ms for fish acclimated to 18 °C and 18 ms for fish ...
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Characterization of Mg2+-regulated TRPM7-like current in human atrial myocytes
... Figure 1A, that current (endogenous) was relatively small and without outward rectification (see also Figure 2C, indi- cated by arrow). While in other, along with endogenous, the much large current with an outwardly ...
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Persistence of pro arrhythmic spatio temporal calcium patterns in atrial myocytes: a computational study of ping waves
... Another manifestation of self-sustaining, spontaneous Ca 2+ waves that derives from the specific geometry of atrial myocytes occurs within a single z-plane under appropriate conditions of refractory period ...
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cGMP stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes
... cardiac myocytes (4, 6), relatively little is known on its ...cardiac myocytes (16, 17) as well as in other preparations (19–21), opened up the possibility to directly examine the role of this enzyme in the ...
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Unifying principles of calcium wave propagation: insights from a three dimensional model for atrial myocytes
... the atrial myocyte sarcolemma therefore activates VGCCs around the cellular periphery, and initially causes a sub-sarcolemmal Ca 2+ rise (10, ...inwards atrial my- ocytes display only a modest ...of ...
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A new potassium ion current induced by stimulation of M2 cholinoreceptors in fish atrial myocytes
... Fig. 4. Effect of intracellular perfusion with PTX on the density of CCh- induced current in atrial myocytes of the crucian carp. PTX was included in pipette solution (PS) 1 and the myocytes were ...
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Tachycardia induced silencing of subcellular Ca2+ signaling in atrial myocytes
... left atrial myo- cytes (Supplemental Figure ...left atrial myocytes was similarly sparse in CTL left atrial myocytes isolated from patients in sinus rhythm and was unchanged in ...
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Original Article Expression changes of small conductance Ca 2+ activated K channel in atrial myocytes caused by calumenin silence
... methyl ester (Fluo-3/AM) by fluorescence spec- trophotometer. Suckling mouse atrial myocytes were loaded with Fluo-3/AM for 10 min. cells were passed through 340 nm filter. Fluoresce- nce emissions were ...
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A study of the pharmacology of G protein-coupled potassium channels in rat atrial myocytes and guinea-pig submucous plexus neurones
... the atrial channel, VanDongen found very httle tonic activity of the Œo-sensitive channels in the absence of G protein, but like KACh the channels were activated by picomolar concentrations of ao ...
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Expression changes of ionic channels in early phase of cultured rat atrial myocytes induced by rapid pacing
... the atrial myocardial cells are isolated under a calcium-free environ- ment and thus intolerant to ...of atrial myocardial cells. In this study, the culture of primary atrial myocardial cells was ...
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Calcitriol downregulates fibroblast growth factor receptor 1 through histone deacetylase activation in HL-1 atrial myocytes
... demonstrated that exogenous FGF-2 increased protein syn- thesis and myocyte sizes in isolated adult rat ventricular myocytes [26]. The hypertrophic effect of human pericar- dial fluid, which was collected from ...
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Nitric oxide regulates the calcium current in isolated human atrial myocytes
... Several main conclusions can be drawn from our experiments: a SIN-1 produces a stimulation of basal ICa; b this effect occurs in the nanomolar range of concentrations and is not mimicked[r] ...
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Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes
... The data in this study should be interpreted with cau- tion because of its potential limitations. First, similar to those in the previous studies, this short-period experiment has used a supra-physiological concentration ...
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Parathyroid hormone like protein is a secretory product of atrial myocytes
... cardiac myocytes represents a calcium- related regulatory function for this stretch-responsive polypeptide in the cardiovascular ...the atrial natriuretic-sodium regulatory axis of the cardiovascular ...
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Name: Elena N. Dedkova, Ph.D.
... 20. Lipsius S.L., Wang Y.G., Ji X., Blatter L.A., Dedkova E.N. Alpha-1 adrenoreceptor stimulation by Phenylephrine stimulates L-type calcium current via nitric oxide production in cat atrial myocytes. ...
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Significance of Na+ current in the excitability of atrial and ventricular myocardium of the fish heart
... of atrial myocytes with pacemaker cells of the sinus venosus, and interaction of ventricular myocytes with myocytes of the atrioventricular canal, is crucial for function of the fish heart ...
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Intracellular lactate signaling cascade in atrial remodeling of mitral valvular patients with atrial fibrillation
... AF, atrial myocytes might more dependent on glycolysis for their ATP production and thus require transport more lactate to mitochondrial oxidation by upregulation ...in atrial myocytes from ...
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β3 adrenergic receptor activation increases human atrial tissue contractility and stimulates the L type Ca2+ current
... human atrial tissue contractility and stimulated the L-type Ca 2+ channel current (I Ca,L ) in isolated human atrial myocytes ...Right atrial tissue specimens were obtained from 57 patients ...
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Effects of temperature on intracellular [Ca2+] in trout atrial myocytes
... In a separate series of experiments, we recorded APs from rainbow trout atrial myocytes (Fig. 1). Cells were stimulated to elicit APs at 7°C, 14°C or 21°C and at a frequency that corresponds to the resting ...
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