αv Integrins
The Role of ΑV integrins in Human Skin Tissue Homeostasis, Wound Healing and Squamous Cell Carcinoma
... of αv integrins in keratinocytes ...of αv trafficking. It is also unclear why αv has different localization dependent on the cell ...and αv adhesions in different cell types may reveal ...
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The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development
... in αv integrins express a dramatic vascular ...of αv-deficient mice survive to term but die within hours after ...that αv integrins are essential during blood vessel formation and/or ...
5
Equine Herpesvirus 1 Entry via Endocytosis Is Facilitated by αV Integrins and an RSD Motif in Glycoprotein D
... RGD-binding integrins such as ␣ V  5 or ␣ V  3 and an RSD motif in EHV-1 gD as impor- tant requirements for EHV-1 endocytosis, more research will be necessary to study this complex, multistep process of EHV-1 ...
10
Endothelial α5 and αv integrins cooperate in remodeling of the vasculature during development
... 1 integrins (Carlson et ...v integrins on endothelial cells complete development and ...these integrins in angiogenesis, that they appear to be dispensable on endothelial cells for normal ...
11
Specificity of the VP1 GH Loop of Foot-and-Mouth Disease Virus for αv Integrins
... using integrins derived from the natural hosts of ...to integrins ␣ v  3, ␣ v  6, and ␣ v  ...used integrins of human ...with integrins derived from the natural ...
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α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo
... 1 integrins play an important role in providing structural strength to the blood vessels and in resisting the high pulsatile flow from the ...1 integrins might simply correlate with a specific population of ...
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αv Integrins regulate germinal center B cell responses through noncanonical autophagy
... Although the role of B cell TLRs in promoting effective immunity is increasingly appreciated, the factors that affect TLR signaling in these cells and how these affect immune responses remain poorly understood. Here, we ...
17
Selective ablation of αv integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death
... revealed α v-specific neuroepithelial immunoreactivity, as determined by co-localization with nestin (Fig. 2A-C). The anti- α v immunoreactivity did not colocalize with markers for newly differentiated neurons, such as β ...
12
The role of αv integrins in regulating keratinocyte behaviour.
... v integrins are expressed by many cell types in vivo, but are consistently found in dynamic situations where cells are migrating or tissue being turned over, such as during development, wound healing and the ...
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The Role of αv Integrins during Angiogenesis
... Tumor-secreted growth factors induce cell proliferation, cell invasion, expression of integrin av{33 on vascular cells, and matrix degradation of surrounding extracellular m[r] ...
10
Integrins are not essential for entry of coxsackievirus A9 into SW480 human colon adenocarcinoma cells
... Enteroviruses are common human viruses and endemic in many developing countries. Although most enteroviral infections are subclinical, they may cause a wide spectrum of diseases including mild upper respiratory illness ...
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αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice
... on αv integrins. In mice, lack of integrin αv in the immune system resulted in loss of Th17 cells in the intestine and lymphoid ...that αv integrins on DCs activated latent TGF-β during ...
9
Integrins and their ligands in rheumatoid arthritis
... are increased in the synovial lining layer [5]. Lymphocytes have been shown to attach to other synovial cells by binding to the fi bronectin coating on their cell surface by α4β1 and α5β1 and to some extent by ανβ3 ...
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Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling
... RGD-binding integrins, namely vitronectin and fibronectin, this difference was distinctly ...of integrins by cilengitide treatment resulted in reduced cell adhesion efficacy to culture plastic as well as ...
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Regulation of keratinocyte integrins by scatter factor
... f integrins is their ability to modulate the level o f adhesion rapidly and ...f integrins. This regulation o f integrins is called integrin-affmity ...f integrins at specialised adhesion ...
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Numerical Experiments of Cavitating Flows Around Hydrofoil
... When σ = 0.4, the time dependent response of the cavitation phenomena could by appreciated in Figure (2) for αv and Cp at two control points. The solution shows that the cavity of vapor becomes highly unsteady, ...
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The Correlation between the Endometrial Integrins and Osteopontin Expression with Pinopodes Development in Ovariectomized Mice in Response to Exogenous Steroids Hormones
... different integrins and housekeeping genes revealed that the α4 subunit in endometrium of both ovariectomized mice groups (treated with progesterone and/or estrogen-progesterone) and in different phases of estrous ...
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Integrin αV is necessary for gastrulation movements that regulate vertebrate body asymmetry
... different integrins, including other V integrins, and because there is a dearth of V1-specific antibodies and ...many integrins function as both adhesion and signaling receptors (Hynes, 2002; ...
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Role for the αV Integrin Subunit in Varicella-Zoster Virus-Mediated Fusion and Infection
... of integrins as having a role in VZV gB/gH-gL-mediated membrane fusion and VZV infection and spread in melanoma ...of integrins in HSV-1 entry and EBV glycoprotein-mediated fusion (23, ...
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Molecular imaging of integrins in oncology
... While integrins expressed on endothelial cells are responsible for the regulation of cell motility and survival, those integrins on carcinoma cells increase the metastatic potential of the tumor by ...
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