Axon outgrowth
Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1
... governing axon outgrowth may also be involved in neuronal migration (Hu and Rutishauser, 1996; Wu et ...of axon outgrowth followed by neuronal migration through nuclear ...i.e. axon ...
12
The Caenorhabditis elegans Ephrin EFN-4 Functions Non-cell Autonomously with Heparan Sulfate Proteoglycans to Promote Axon Outgrowth and Branching
... affect axon outgrowth (Table ...and axon guidance (Nakao et ...neurite outgrowth, nor did they affect kal-1(gf) ectopic axon ...neurite outgrowth defects, similar to efn-4 ...
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RPM 1 and DLK 1 regulate pioneer axon outgrowth by controlling Wnt signaling
... anterior-posterior axon growth is RPM-1, a founding member of the Pam/Highwire/RPM-1 protein family (Grill et ...morphology, axon overgrowth, impaired presynaptic differentiation, and internalization of ...
12
The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development
... in axon outgrowth, several + TIPs have been implicated in participating in growth cone steering decisions in response to extracellular ...in axon outgrowth led us to ask whether TACC3 ...
10
Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization
... outgrowth and turning in cortical neurons [9, 11, 12]. An independent branch of Ca 2+ -dependent CaMK family comprises the CaMKI subfamily (α, β, γ, and δ), which may form several parallel kinase cascades ...
11
The Neural Receptor Protein Tyrosine Phosphatase DPTP69D Is Required During Periods of Axon Outgrowth in Drosophila
... We have isolated and characterized a series of 18 chemically induced alleles of Ptp69D ranging in strength from viable to worse than null, which represent unique tools for probing the structure, function, and signaling ...
14
Prdm14 acts upstream of islet2 transcription to regulate axon growth of primary motoneurons in zebrafish
... initial axon extension, but leads to premature branching and shortened axon outgrowth ...CaP axon development (Chitramuthu et ...of axon targeting in Drosophila (Endo et ...
10
The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans
... Besides outgrowth, in neurons UNC-40-mediated signaling plays an important role in orienting synapse assembly, axon arborization, and extra- synaptic neurosecretory terminals (Colon-Ramos et ...Like ...
34
Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1
... chemorepellent axon guidance; however, their role during axonal chemoattraction is ...assayed axon outgrowth and turning towards netrin ...1-mediated axon outgrowth and chemoattractive ...
10
Cellular and Molecular Analyses of Neural and Synaptic Development in Zebrafish
... motor axon outgrowth and neuromuscular synaptogenesis are not altered when AChRs are blocked or ...motor axon growth cones and filopodia, and our data suggest that such cues are patterned ...
258
Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin activity
... (blue) axon outgrowth and number of Lhx2/9 + commissural neurons ...initiate axon growth at the same ...initiated axon growth (probability of similarity between the control and experimental ...
10
PubMedCentral-PMC4809367.pdf
... neurite outgrowth and elongation, whereas antisense nucleotides against myosin IIA-reduced neurite retraction in neuroblastoma cells (Wylie et ...in axon outgrowth, superior cervical ganglia neurons ...
51
Caenorhabditis elegans WASP and Ena/VASP Proteins Play Compensatory Roles in Morphogenesis and Neuronal Cell Migration
... We report here that WASP and Ena/VASP family proteins play overlapping roles in C. elegans morphogen- esis and neuronal cell migration. Specifically, these studies demonstrate that UNC-34/Ena plays a role in ...
12
The conserved kinase UNC 51 acts with VAB 8 and UNC 14 to regulate axon outgrowth in C elegans
... directed axon guidance ...directed axon guidance requires the long form, ...CAN axon guidance, we used the vab-8(ev411) mutation, which disrupts the function of VAB- 8L, but not VAB-8S (Wolf et ...
10
Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation
... motor axon outgrowth has been a key question since these phenomena were first observed (Bronner-Fraser, 1986; Keynes and Stern, 1984; LeDouarin and Kalcheim, 1999; Rickmann et ...
10
The impact of metallothionein II on microglial response to tumor necrosis factor alpha (TNFα) and downstream effects on neuronal regeneration
... Metallothionein I/II represents an unusual family of metal-binding proteins; both MTI and MTII isoform share a very similar structure as well as have a range of neurotrophic properties. Our group has previously dem- ...
9
An UNC 40 pathway directs postsynaptic membrane extension in Caenorhabditis elegans
... an axon ventrally during the fourth larval stage (Adler et ...initial outgrowth and their ultimate extension to the ventral midline ...consider outgrowth as misguided if the adult HSN axon is ...
12
Deimination restores inner retinal visual function in murine demyelinating disease
... Neurite growth and retraction has only recently been recognized as a much more dynamic and locally controlled process (28). There is growing realization that PTMs could be important regulators of local dendritic protein ...
12
Nell2 regulates the contralateral versus ipsilateral visual projection as a domain specific positional cue
... Recently, Nell2 has been shown to repel murine spinal commissural axons through the Robo3 receptor and steer them towards and across the midline of the spinal cord (Jaworski et al., 2015). In the developing mouse retina, ...
9
Control of head movement in the locust schistocerca gregaria
... in Crustacean ousels* * twood doylo and luyth 1%5 * but here the axon elooiting the response is reported to a alow and not a fast axon* Evidence for the fast nature of an axon elicitin g[r] ...
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