B. anthracis
Non-Toxin-Producing Bacillus cereus Strains Belonging to the B. anthracis Clade Isolated from the International Space Station
... from B. anthracis by low- resolution molecular typing methods ...toxin; B. cereus), biowarfare (virulence plasmids; B. anthracis), and economic (biological insecticides; ...of B. ...
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Characterization of Bacillus cereus Isolates Associated with Fatal Pneumonias: Strains Are Closely Related to Bacillus anthracis and Harbor B anthracis Virulence Genes
... Despite the fact that B. anthracis toxin genes are found in several of the B. cereus isolates associated with severe pneu- monia in metal workers, we do not know whether these genes are appropriately ...
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Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines
... ing B. anthracis -associated shock, we employed this canine model to also investigate the effects of HS alone or together with raxi for shock caused by lethal ET challenge in one study (Study-1) and lethal ...
14
Role of the Putative Polysaccharide Deacetylase BA1836 from B anthracis in Spore Development and Germination
... 7702 B. anthracis cells carrying this construct into sporulation-inducing medium and collected samples at vari- ous time points during ...7702 B. anthracis cells, in which ba 1836 -lacZ was ...
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Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support
... The latest treatment tested in this study that was started and completed 5 and 11 h, re- spectively, following the initiation of toxin challenge had beneficial effects comparable to earlier treatment times. However, even ...
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Genome Wide Single Nucleotide Polymorphism Typing Method for Identification of Bacillus anthracis Species and Strains among B cereus Group Species
... among B. anthracis strains, including Japanese isolates, and constructed a sim- plified SNP-typing method using tag SNPs to facilitate the identification of strain lineage based on the whole-genome sequence ...
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Single Nucleotide Repeat Analysis for Subtyping Bacillus anthracis Isolates
... Bioinformatics and primer design. The B. anthracis sequences used in the in silico SNR analysis are summarized in Table 2. The fasta format sequences were processed by use of a perl script to identify all ...
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Detection of the Bacillus anthracis gyrA Gene by Using a Minor Groove Binder Probe
... Traditionally, B. anthracis has been distinguished from other members of the ...identify B. anthracis are plasmids pXO1 and pXO2 (5, 7, ...of B. anthracis and carry genes that ...
7
Bacillus pumilus: Possible Model for the Bioweapon Bacillus anthracis
... The misuse of Bacillus anthracis as a bioweapon continues to be a serious concern. Medical personnel and researchers are served well if appropriate non-pathogenic anthrax simulants can be used as countermeasures ...
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Detection of Bacillus anthracis DNA by LightCycler PCR
... additional 18 to 24 h may be required for bacterial growth before the LightCycler test can be performed. We are currently evaluating the utility of this assay for detection of B. anthracis directly from ...
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Questionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax
... the B. anthracis culture supernatant contains a “protective antigen” dates before the precise identification of the three toxin moieties in the 1950s by Harry Smith’s group ...
6
The Genetic Diversity and Evolution of Francisella tularensis with Comments on Detection by PCR
... Bacillus anthracis, Francisella tularensis, Yersinia pestsis, Brucella species, and ...for B. anthracis, Brucella species, ...from B. anthracis, ...
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Identifying experimental surrogates for Bacillus anthracis spores: a review
... among B. anthracis relatives [155-157] and within B. anthracis, as shown by differences between the Vollum and Sterne strains ...and B. thuringien- sis all possess filaments, whereas ...
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Genetic Characterization of Bacillus anthracis 17 JB strain
... Results and Conclusion: In SNPs typing, the originally French 17JB strain represented the A.Br. 008/009 subgroup. In Levy's genotyping method, 843, 451 and 864 bp long fragments were identified at AA03, AJ03 and AA07 ...
5
Response of the Clinical Microbiology Laboratory to Emerging (New) and Reemerging Infectious Diseases
... B. anthracis test kits or ASRs are commercially available from manufacturers for use with several real-time PCR testing ...Bacillus anthracis Detection kit (Roche Applied Science, Indianapolis, ...
7
MICs of Selected Antibiotics for Bacillus anthracis, Bacillus cereus, Bacillus thuringiensis, and Bacillus mycoides from a Range of Clinical and Environmental Sources as Determined by the Etest
... Bacillus anthracis to cause infec- tions; the increasing rarity of human anthrax in industrialized, developed countries as a result of effective control programs over the past half century; and the high ...
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Antimicrobial Susceptibility Testing of Bacillus anthracis: Comparison of Results Obtained by Using the National Committee for Clinical Laboratory Standards Broth Microdilution Reference and Etest Agar Gradient Diffusion Methods
... Safety. Due to the potential aerosol hazard, all antimicrobial susceptibility tests were performed in a biosafety level 3 (BSL 3) laboratory within a class II biological safety cabinet and in full compliance with all ...
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CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis
... of B. anthracis to CXCL10. (A) B. anthracis parent strain membrane depolarization occurs after exposure to CXCL10 or ...(B) B. anthracis ⌬ ftsX mutant membrane ...
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A case report of inhalation anthrax acquired naturally
... In the early 1900s, the human cases of respiratory anthrax in the United States occurred mainly in those who had contact with textiles and leather industry and was named as Wool sorter disease. In the late twenti- eth ...
5
Bacillus anthracis Diversity in Kruger National Park
... In this set of isolates, it is interesting to note that the most informative marker was not from the pXO1 plasmid VNTR (Fig. 1), in contrast to what was found in the worldwide study (9). In fact, the pXO1 VNTR marker had ...
5