B-cell activating factor
Serum B cell–activating factor (BAFF) level in connective tissue disease associated interstitial lung disease
... BAFF: B cell – activating factor belonging to the tumour necrosis factor family; KL-6: Krebs von den Lungen-6; SP-D: surfactant protein D; CTD-ILD: interstitial lung disease associated ...
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The Correlation Between Non-Hodgkin Lymphoma and Expression Levels of B-Cell Activating Factor and Its Receptors
... B-cell activating factor regulates the survival, proliferation and differentiation of B cells main- ly through binding with the three cell-surface re- ceptors (TACI, BCMA and ...
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Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection
... he B cell-activating factor (BAFF) receptor (BAFFR) is critical for B cell development (1, ...severe B cell lymphopenia and impaired immunoglobulin production ...
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B Cell Activating Factor Characterization and Use as a Biomarker in Dogs with Primary Immune-Mediated Thrombocytopenia.
... or B cell maturation antigen (BCMA) and contributes to B cell maturation, T cell independent class switching, and plasma cell survival (Bossen & Schneider, ...
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B lymphocytes and B cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis
... of B cells in the expression of collagen and profibrotic markers by SScHDF, we first evaluated mRNA levels of COL1A1, COL1A2, and COL3A1, which encode type I and type III collagens in ...with B cells for 3 ...
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B cell activating factor targeted therapy and lupus
... Autoreactive B-cell receptors are generated either when random immunoglobulin variable gene rearrangement occurs in the bone marrow or as a consequence of somatic mutation that occurs mainly in the germinal ...
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Low numbers of blood and salivary natural killer cells are associated with a better response to belimumab in primary Sjögren’s syndrome: results of the BELISS study
... cytokine B-cell activating factor (BAFF), also called B-lymphocyte stimulator [3], is involved in the pathogenic mechanism of B-cell activa- ...in B-cell ...
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<p>Multispecialty approach for improving outcomes in juvenile dermatomyositis</p>
... clonal B- and T-cell expansion in the in fl amed ...immune cell activation and ...necrosis factor (TNF) receptor 2 with disease activity has been con fi rmed in ...vascular cell adhesion ...
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Clinical associations of serum interleukin 17 in systemic lupus erythematosus
... BAFF: B cell activating factor of the tumour necrosis factor family; BAFF-R: BAFF-receptor; BAFF-Tg: BAFF transgenic; CD: Crohn ’ s disease; CNS: central nervous system; CRP: C-reactive ...
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Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury
... and B cell survival and proliferation ...9], B cells, and activated T cells [10] ex- press APRIL, and APRIL can interact with transmem- brane activator and CAML interactor (TACI), B ...
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Peripheral regulatory cells immunophenotyping in Primary Sjögren's Syndrome: a cross sectional study
... BAFF: B cell activating factor; BCR: B cell receptor; CpG: cytosine-phopsphate-guanosine; DC: dendritic cell; DCregs: indoleamine 2,3-dioxygenase-expressing dendritic ...
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Serum BAFF and APRIL levels in patients with IgG4 related disease and their clinical significance
... BAFF: B cell-activating factor of the tumor necrosis factor family; BCMA: B cell maturation antigen; BLys: B-lymphocyte stimulator; CA II: carbonic anhydrase II; ...
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Immunopathologic differences of Sjögren's syndrome versus sicca syndrome in HCV and HIV infection
... of B-cell activating factor (BAFF) and a proliferation- inducing ligand (APRIL) ...with B-cell ...erent cell types, including dendritic cells, T lympho- cytes and ...
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Disturbance of cytokine networks in Sjögren's syndrome
... (Th) cell universe and the discovery of numerous B lymphocyte-derived ...Furthermore, B lymphocyte polarization into type-1 B eff ector (Be1) and Be2 cells and B-cell modulating ...
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Emerging technologies in autoantibody testing for rheumatic diseases
... In patients seen in a pediatric setting, detection of large numbers of analytes from small volume samples is also especially useful. An array displaying 140 autoanti- gens was used to compare pediatric patients with ...
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Fichtner, Miriam Franziska Laura (2018): Features of the two isoforms of TACI/TNFRSF13B in soluble and membrane-bound form. Dissertation, LMU München: Medizinische Fakultät
... (B-cell activating factor) und APRIL (A proliferation- inducing ligand) regulieren das Überleben der B-Zellen durch die Bindung an die drei Rezeptoren TACI (transmembrane activator and ...
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PD L1(hi) B cells are critical regulators of humoral immunity
... to B-cell depletion therapy (aCD20 monoclonal antibody (mAb) ...post B-cell depletion therapy, was attributed to elevated expression of the B-cell activating factor ...
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Review of biomarkers in systemic juvenile idiopathic arthritis: helpful tools or just playing tricks?
... ). b Prognostic biomarkers for flare ( P1 ), increased disease activity or discriminating active disease from inactive ( P2 ), for macrophage activation syndrome (MAS) or discriminating MAS from SJIA flare ( P3 ), ...
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NF-κB signaling and its relevance to the treatment of mantle cell lymphoma
... Activated B cell-like diffuse large B cell lymphoma; BAFF/ TNFSF13B: B cell-activating factor; BAFFR: B cell-activating factor receptor; ...
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Rationale of anti CD19 immunotherapy: an option to target autoreactive plasma cells in autoimmunity
... targeting B cells has been approved for treatment of non-Hodgkin lymphoma, rheumatoid arthritis and anti-neutrophil cytoplasmic antibody-associated vasculitides and has led to reappreciation of B-lineage ...
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