B-Cell acute lymphoblastic leukemia
Original Article CD317 is over-expressed in B-cell chronic lymphocytic leukemia, but not B-cell acute lymphoblastic leukemia
... B-cell acute lymphoblastic leukemia (B-ALL) is a neoplasm of B cell precursors ...new B-ALL cases are diagnosed each year. 75% of B-ALL cases occur in ...
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The Role of PU.1 and Spi-B in B Cell Acute Lymphoblastic Leukemia
... pediatric B cell acute lymphoblastic ...human leukemia cell lines AT-2 and REH, which express ETV6-RUNX1, suggested that SPIB was one of the top of the genes that were up ...
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Clinical use of blinatumomab for B-cell acute lymphoblastic leukemia in adults
... refractory B-cell acute lymphoblastic leukemia have a dismal prognosis with a short median overall survival that can be measured in ...stem cell transplantation remains the only ...
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Childhood pre B cell acute lymphoblastic leukemia with translocation t(1;19)(q21 1;p13 3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report
... ALL: Acute lymphoblastic leukemia; aMCB: Array-proven high-resolution multicolor banding; B-ALL: B cell acute lymphoblastic leukemia; BM: Bone marrow; Cdks: ...
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Recent advances in the biology and treatment of B-cell acute lymphoblastic leukemia
... aimed at higher sensitivities, and easy and broad applicabil- ity. In a recent study, Wood et al compared HTS of IGH and TRG genes vs MFC for MRD detection at the end of induction chemotherapy in pediatric patients with ...
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Prediction of outcomes by early treatment responses in childhood T-cell acute lymphoblastic leukemia: a retrospective study in China
... than B-ALL patients [8, 10, ...established leukemia groups [19 – ...on B-ALL, whereas MRD studies in T-ALL were ...of leukemia cells was found in T-ALL pa- tients and MRD risk group classified ...
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Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia
... in leukemia have not been reported. FEM1b (feminization-1 homolog b) has been identified as a binding partner for PHTF1 ...T-ALL cell lines, we performed experiments involving the down regulation or ...
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Emerging roles of epithelial-mesenchymal transition in hematological malignancies
... ALL: acUte lymphoblastic leukemia; AML: Acute myeloid leukemia; BCL-6: B-cell lymphoma 6 protein; Bmi1: B cell-specific Moloney murine leukemia virus ...
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Case Report B-acute lymphoblastic leukemia occurring in two pediatric patients with a history of prior Wilms tumors
... Therapy-related acute leukemia (t-AL) is an observed carcinogenesis due to the toxic side effects of ion- izing radiation and/or conventional chemotherapy for primary ...therapy-related acute myeloid ...
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Induction of human B cell antigens in non T cell acute lymphoblastic leukemia
... non-T cell acute lymphoblastic leukemia (ALL) express an antigen (B1) found on all normal B ...Non-T cell ALL lines and tumor cells isolated from patients with non-T cell ...
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Expression of the polycomb group gene Bmi1 does not affect the prognosis of pediatric acute lymphoblastic leukemia
... precursor B leukemic cells is related to the clinical course, cell profile, and ...In acute lymphoblastic leukemia, it was reported that CD90+/CD110+ cells in acute ...
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Pharmacokinetics and dose adjustment of etoposide administered in a medium-dose etoposide, cyclophosphamide and total body irradiation regimen before allogeneic hematopoietic stem cell transplantation
... adult acute lymphoblastic leukemia: a prospective, randomized trial comparing allogeneic versus autologous bone marrow transplantation and testing the impact of recombinant interleukin-2 after ...
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T cell senescence and CAR-T cell exhaustion in hematological malignancies
... Treg cell mechanism of forcing T cells into senescence ...Treg cell accumulations in hematological malignancies such as acute myeloid leukemia (AML), acute lymphoblastic ...
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Heterogeneity of cultured leukemic lymphoid progenitor cells from B cell precursor acute lymphoblastic leukemia (ALL) patients
... with B cell precursor acute lymphoblastic leukemia ...leukemic B cell precursors from patients with a pseudodiploid or near-diploid karyotype with structural chromosomal ...
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Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses
... Metastases to the breast and axilla are rare and account for approximately 2% of all mammary malignancies [1,2]. The most common metastatic lesion to involve the breast is a metastasis from a contralateral mammary cancer ...
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A high complex karyotype involving eleven chromosomes including three novel chromosomal aberrations and monoallelic loss of TP53 in case of follicular lymphoma transformed into B-cell lymphoblastic leukemia
... common B- cell non-Hodgkin’s lymphoma (NHL) with a relatively indo- lent clinical course, accounting for 20–30% of all NHL ...large B-cell lymphoma (DLBCL) [2]. Furthermore, ...
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Intracranial hemorrhage in adult patients with hematological malignancies
... There were some limitations to this study. First, we tried to investigate all the adult patients with hematological malignancies. However, this study is a retrospective cohort in a single university hospital between 2001 ...
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... Results: Fusion gene was detected in 45 patients. In 1–10 years age group, 26/32 (81%) subjects had good response, while 75% in <1 year age group and 7/9 (78%) in ≥10 years age group had poor response. 5/7 (71%) ...
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Histiocytic sarcoma combined with acute monocytic leukemia: a case report
... A 62-year-old Chinese man presented with gingival bleeding in August 2012. Physical examination revealed skin ecchymosis and enlarged lymph nodes in his cer- vical, axillary, and inguinal areas, the largest of which was ...
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T cell receptor gamma and delta rearrangements in hematologic malignancies Relationship to lymphoid differentiation
... T cell receptor delta was frequently rearranged while T cell receptor gamma was in the germline ...T cell receptor delta and gamma rearrangements were ...
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