B-cell leukemia-2
STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia
... of cell surface (s) IgM, and a defective ...Ca 2+ level that can be enhanced upon sIgM triggering. The elevated Ca 2+ signaling in the CLL group with progressive disease was associated with an ...
13
MYC as therapeutic target in leukemia and lymphoma
... dependent B-cell differentiation ...naïve B-cell moves to a fol- licle where it intensely proliferates to form a germinal ...Those B-cells that fail selection die by apoptosis, whereas ...
17
Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)
... audible thyroid bruit. Lymph node packages with the diameter of 5 cm were palpable on the lateral surface of the neck, particularly on its left side. Hormone tests revealed normal levels of free thyroid hormones and ...
6
Hairy cell leukemia: A retrospective study on 11 patients in the Western of Iran.
... Hairy cell leukemia (HCL) is a chronic B-cell lymphoid leukemia characterized by pancytopenia, splenomegaly, myelofibrosis and the presence in peripheral blood, bone marrow and spleen ...
5
Original Article CD317 is over-expressed in B-cell chronic lymphocytic leukemia, but not B-cell acute lymphoblastic leukemia
... mature B cells, we pro- cured healthy human bone marrow, and flow cytometry was used to determine the mean fluorescence intensity (MFI) of CD317 on vari- ous subsets of developing B ...Stage 2 ...
9
Clarification of the molecular pathway of Taiwan local pomegranate fruit juice underlying the inhibition of urinary bladder urothelial carcinoma cell by proteomics strategy
... gene 2; Akt/PKB: protein kinase B; BAG2: BCL2-associated athanogene 2; BCL 10: B-cell lymphoma/leukemia 10; CAPZA1: F-actin-capping protein subunit alpha-1; CFL1: C ofilin; DUT: ...
10
The human T-cell leukemia virus type I Tax protein induces apoptosis which is blocked by the Bcl-2 protein.
... Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death.. Adult T-cell leukemia antigen in an ATL cell line and[r] ...
6
The Role of PU.1 and Spi-B in B Cell Acute Lymphoblastic Leukemia
... pediatric B cell acute lymphoblastic leukemia, representing 25% of the ...human leukemia cell lines AT-2 and REH, which express ETV6-RUNX1, suggested that SPIB was one of the top ...
88
Original Article Knockdown of eukaryotic translation initiation factor 3 subunit B inhibits cell proliferation and migration and promotes apoptosis by downregulating WNT signaling pathway in acute myeloid leukemia
... of cell growth-regulat- ing protein synthesis, which contributes to the oncogenic progression of several cancers ...AML cell lines compared with human primary ...oncogenic cell activities, which was ...
8
<p>IFN-γ and TNF-α aggravate endothelial damage caused by CD123-targeted CAR T cell</p>
... Figure 2 CART123 exerts potent anti-leukemia and anti-endothelium activities in ...NALM-6 cell lines and primary AML cells from two patients (AML-2 and AML-3) was analyzed by flow ...myeloid ...
19
Allogeneic cellular immunotherapy for chronic B-cell leukemia
... hematopoietic targets and CLL-APC (clone 2.45, clone 2.105 and clone 3.62) and not against primary CLL. These CTL clones may be able to recognize the CLL cells, once these leukemic cells become activated or start ...
141
Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses
... breast and 12.6±2.5 kPa for the right breast (Figs. 1-2). Shear wave sonoelastography provides quantitative elasticity measurements, thus adding complementary information that potentially could help in breast ...
5
High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia
... lymphoblastic leukemia; aMCB: Array-proven multicolor-banding; AML: Acute myelogenous leukemia; BAC: Bacterial artificial chromosome; B-ALL: B-cell ALL; Bp: Basepairs; CLL: Chronic ...
12
Emerging roles of epithelial-mesenchymal transition in hematological malignancies
... lymphoblastic leukemia; AML: Acute myeloid leukemia; BCL-6: B-cell lymphoma 6 protein; Bmi1: B cell-specific Moloney murine leukemia virus integration site 1; ChIP: ...
8
Residual normal B-cell profiles in monoclonal B-cell lymphocytosis versus chronic lymphocytic leukemia
... pre-GC B-cell subsets from both MBL and CLL subjects are required to fully con fi rm this ...of B-cell subsets expressing distinct Ig-subclasses was observed among both antigen- experienced ...
5
Non-coding RNAs: a key to future personalized molecular therapy?
... control cell differentiation or ...gene B-cell lymphoma 2 (BCL-2) [28], myeloid cell leukemia sequence 1 (MCL1), cyclin D1 (CCND1) and wingless-type MMTV integration site ...
10
Histiocytic sarcoma combined with acute monocytic leukemia: a case report
... T-cell, B-cell, and myeloid lineage ...but 2 % blasts ...monocytic leukemia (AMoL-M5), and treated by CAG regimen + decitabine, but died of severe pneumonia and hepatic ...stem ...
6
Case Report Splenic diffuse red pulp small B-cell lymphoma in an Asian female patient with review of literature
... The differential diagnosis between SDRPL and HCL-v remains debatable due to their simi- lar clinical-pathological presentations. Nonethe- less, there are some clear differences between these two diseases. For instance, ...
6
www.ijcep.com /IJCEP1002005 Case Report An uncommon case of de novo CD10 CD5 mantle cell lymphoma mimics follicle center B cell lymphoma
... Because of the differences in treatment strat- egy and clinical outcome, it is important to dis- tinguish MCL from germinal center B-cell- derived lymphomas. In most cases, this distinc- tion is ...
7
Characterisation of lens epithelium derived growth factor isoforms in chronic lymphocytic leukemia: Studies and significance
... The aim of this chapter was to develop a method that could be used to examine how alternative splicing affects the ability of the different isoforms of LEDGF to participate in unique and distinct complexes, rather than ...
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