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B-Lymphocytes

First Days in the Life of Naive Human B Lymphocytes Infected with Epstein Barr Virus

First Days in the Life of Naive Human B Lymphocytes Infected with Epstein Barr Virus

... to B-cell activation, cell cycle entry, or early cell ...naive B lymphocytes were infected with this mutant EBV, termed ΔEBNA1 (6285), or with the reference wild-type strain ...of B cells ...

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Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma

Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma

... B lymphocytes infected with HHV-8 are a potential source of in- fectious virus as well as inflammatory cytokines and chemokines that drive the oncogenic process of KS, yet little direct evidence exists to ...

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Trafficking of adoptively transferred B lymphocytes in B lymphocyte deficient mice

Trafficking of adoptively transferred B lymphocytes in B lymphocyte deficient mice

... B lymphocytes recirculate in the body along defined routes as they patrol the body in search of invading ...naive B cells enter secondary lymphoid organs from the blood and migrate through the T-cell ...

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Positive and negative functions of B lymphocytes in tumors

Positive and negative functions of B lymphocytes in tumors

... some B lymphocytes can express the death-inducing molecule Fas ligand (FasL) and kill cells ...by B cells was first reported in 1996 [40]. Upon activation, mouse B cells lead to FasL ...

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Original Article Histopathological features of central nervous system in pediatric cases of fatal hand, foot and mouth disease

Original Article Histopathological features of central nervous system in pediatric cases of fatal hand, foot and mouth disease

... lymphocytes and macrophages/microglia cells in the midbrain/pons, medulla oblongata and spinal cord of HFMD patients ...CD8+T lymphocytes, B lymphocytes and macrophages/microglia cells in the ...

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Autoantibodies to B Lymphocytes in a Patient with Hypoimmunoglobulinemia: CHARACTERIZATION AND PATHOGENIC ROLE

Autoantibodies to B Lymphocytes in a Patient with Hypoimmunoglobulinemia: CHARACTERIZATION AND PATHOGENIC ROLE

... and lymphocytes from immunodeficiency patients showed that these antibodies reacted with B ...stimulated B cells appear to lose this ...from B-derived lymphomas and prolymphocytic leukemias ...

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Failure of heavy chain glycosylation of IgG in some patients with common, variable agammaglobulinemia

Failure of heavy chain glycosylation of IgG in some patients with common, variable agammaglobulinemia

... circulating B lymphocytes which synthesized normal amounts of IgG in tissue culture but failed to secrete the newly synthesized ...The B lymphocytes of these patients fail to incorporate ...

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Memory AND effector cells in children with bacterial infections of the gastrointestinal and respiratory tracts

Memory AND effector cells in children with bacterial infections of the gastrointestinal and respiratory tracts

... and B lymphocytes in the peripheral blood from the bacteria-infected children com- pared with the uninfected ...contrast, B lymphocytes, which are part of the adaptive immune system, produce ...

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B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines

B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines

... with B lymphocytes corroborate those of Filaci et al, who first described “spontaneous lymphocyte transgenesis (SLT)”, of B cells upon co- culture of peripheral blood lymphocytes with plasmid ...

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Production of lymphotoxin by isolated human tonsillar B lymphocytes and B lymphocyte cell lines

Production of lymphotoxin by isolated human tonsillar B lymphocytes and B lymphocyte cell lines

... tonsillar B cells and B cell lines was examined by Northern blots and cytotoxicity assays, ...tonsillar B cells, phorbol myristate acetate (PMA) or Staphylococcus aureus Cowan l (SAC) alone induced ...

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Multiple Mechanisms of Immune Suppression by B Lymphocytes

Multiple Mechanisms of Immune Suppression by B Lymphocytes

... by B lymphocytes was first reported on human and mouse B lymphoma cell lines ...on B-chronic lymphocytic leukemia cells and multiple myeloma cells as well as on nontransformed mouse and human ...

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Activation of Human B Lymphocytes after Immunization with Pneumococcal Polysaccharides

Activation of Human B Lymphocytes after Immunization with Pneumococcal Polysaccharides

... By 2 wk after immunization, spontaneous anti-PPS antibody production in vitro was no longer detected. Subsequent stimulation of lymphocytes in culture with a wide range of concentrations of specific antigen did ...

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Memory CD4+ T-Lymphocyte Loss and Dysfunction during Primary Simian Immunodeficiency Virus Infection

Memory CD4+ T-Lymphocyte Loss and Dysfunction during Primary Simian Immunodeficiency Virus Infection

... T lymphocytes in these monkeys. The fraction of memory CD4 ⫹ T lymphocytes (CD95 ⫹ ) that produced IFN- ␥ or IL-2 in response to SEB was assessed by intracellular staining at regular intervals following ...

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A mutant v-rel with increased ability to transform B lymphocytes.

A mutant v-rel with increased ability to transform B lymphocytes.

... As a biochemical correlate of the enhanced transforming activity, we have shown that the serine at position 40 increases the ability of v-Rel to bind a k B site. This finding is consistent with the observation ...

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Pure Choriocarcinoma of Testis with Tumor Infiltrating Lymphocytes and Granulomas

Pure Choriocarcinoma of Testis with Tumor Infiltrating Lymphocytes and Granulomas

... Pure choriocarcinoma is very rare in the testes, and host immune responses including tumor infiltrating lymphocytes are unusual in choriocarcinoma. This study reports a case of pure testicular choriocarcinoma with ...

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The defect of SFRP2 modulates an influx of extracellular calcium in B lymphocytes

The defect of SFRP2 modulates an influx of extracellular calcium in B lymphocytes

... splenic B cells was observed in the time-course experiments after BCR stimulation with anti-IgM (0, 1, 5, 20, and 60 min) (Figure ...splenic B cells decreased after 5 min stimulation compared with Sfrp2 +/+ ...

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Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes

Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes

... T lymphocytes, but not B lymphocytes, also respond chemotactically to Ox- LDL, showing a threefold increase over control and an optimum response at ...

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Genome wide profiling in treatment naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes

Genome wide profiling in treatment naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes

... in B-lymphocytes, PSORS1C3 (B), PCDH12 (C), and JRK (D), that displayed similar levels of methylation in early RA patients and healthy individuals but which were identified as differentially ...

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Antigen heterogeneity of human B and T lymphocytes

Antigen heterogeneity of human B and T lymphocytes

... (thymus-derived) lymphocytes, an antispleen antiserum was absorbed with cellf from five B- (bone marrow- derived) cell ...blood lymphocytes and 40-50% of tonsil cells, so that there was a ...

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CD4+Foxp3+ regulatory T cells prolong drug induced disease remission in (NZBxNZW) F1 lupus mice

CD4+Foxp3+ regulatory T cells prolong drug induced disease remission in (NZBxNZW) F1 lupus mice

... total lymphocytes (A) and average percentage of CD4+ T cells (B) and CD19+ B cells (C) among lymphocytes in the peripheral blood of (NZBxNZW) F1 mice with active disease before and after ...

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