B NO induced post translational modifications
Aberrant post translational protein modifications in the pathogenesis of alcohol induced liver injury
... aberrant post-translational ...protein modifications with potential functional damage to protein [11] as well as impact the function of various metabolic ...altered post- translational ...
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Regulation of pannexin channels by post-translational modifications
... Two studies have suggested that Panx1 can be opened by the activity of sarcoma (Src) family kinases (SFK) in response to iono- tropic receptors. In Panx1 and P2X7 expressing J778 macrophages, the SFK inhibitor, PP2 ...
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Post-translational modifications and mass spectrometry detection
... ethanol- induced oxidative stress, it was shown that HNE consistently modified heat shock proteins 72 and 90 (HSP72 and HSP90) (235, 236), suggesting a role of HNE in compromising protein ...
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An investigation into the post-translational modifications of Annexin VI
... fibroblasts induced to cycle from quiescence with foetal calf serum ...T-lymphoblasts induced to cycle with recombinant interleukin-2 (rIL-2) (Moss et a i , ...
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Investigation of post-translational modifications in type 2 diabetes
... 103. Park J, Kwon H, Kang Y, Kim Y. Proteomic analysis of O-GlcNAc modifica- tions derived from streptozotocin and glucosamine induced beta-cell apoptosis. J Biochem Mol Biol. 2007;40(6):1058–68. 104. Akimoto Y, ...
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Proteomics of protein post translational modifications implicated in neurodegeneration
... and interferon stimulated gene ISG15 are upregulated to deal with cellular or systemic stress such as reactive oxygen-induced misfolding of proteins, ER-associated stress, or an increase in protein misfolding ...
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Post translational modifications of HOX proteins, an underestimated issue
... hHOXA10 is phosphorylated during myeloid blood cell lineage differentiation induced by IFN g . This phosphorylation decreases the binding of hHOXA10 to cis-regulatory elements of the CYBB and NCF2 genes encoding ...
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Functional role of post-translational modifications of Sp1 in tumorigenesis
... and induced apoptosis in ERα-positive breast cancer cells, and increase p53 expression as a result of enhanced binding of the ERα/Sp1 complex to the p53 promoter region ...
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Coordinated of Post-Translational Modifications of Yeast Transcriptional Activator Gcn4
... 1.8 Objectives: We hypothesize that SUMO modification of Gcn4 takes place after it binds DNA, which then stimulates the removal of the activator from induced promoters by facilitating its Cdk8 and ...
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Myoglobin Post-translational Modifications and Fresh Beef Color Stability
... In the first experiment, Mb PTMs in beef longissimus lumborum (LL) muscle during postmortem aging and their influence on fresh beef color stability were examined. Beef LL muscle from nine (n = 9) beef carcasses (24 h ...
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Post-translational modifications of RINT1 (RAD50-interacting protein 1)
... 97 (FANCD2), which is targeted to the nuclear foci and co-localizes with BRCA1 upon monoubiquitination in the S phase of the cell cycle (Garcia-Higuera, Taniguchi et al. 2001; Gregory, Taniguchi et al. 2003; Nakanishi, ...
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Post-translational Modifications are Required for Circadian Clock Regulation in Vertebrates
... In this context, it was previously reported that the MKK7–JNK signaling pathway is an essential regulator of periodicity in the cellular clocks of mammals. The MKK7– JNK signaling pathway induces PER2 phosphorylation and ...
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Motifs tree: a new method for predicting post-translational modifications
... In our setup, an individual is a token sequence of variable length. The initial population is randomly created by generating n individuals with m tokens, randomly drawn from the category of token described in the model ...
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Functions and regulation of Hdmx and post-translational modifications in drug sensitivity and cancer.
... Hdmx Post-translational modifications of the members of the p53 pathway, mediated by several upstream activators, contribute to p53 activation upon DNA damage 11 ...
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Plant cytoplasmic GAPDH: redox post-translational modifications and moonlighting properties
... tion, induced GAPC1 protein accumulation in a similar way as Cd treatments, suggesting that GAPC1 promoter activation may be mediated by unknown oxidized elements of the cyto- plasm, rather than Cd itself (Vescovi ...
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HIV latency reversing agents act through Tat post translational modifications
... appropriate post-translational modification can be induced by LRAs in rCD4+ T cells, particularly since the long non-coding RNA NRON, which is highly expressed in rCD4+ T cells, can target Tat for ...
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Functional decorations: post-translational modifications and heart disease delineated by targeted proteomics
... is induced by changes in the local environment, such as cellular pH; and, less commonly, physical, in which proteins are targeted for cleavage or degradation, for example matrix metalloproteinases in extracellular ...
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Covalent Post Translational Modifications
... lysine modifications are highly regulated during zebrafish development of the following translation is ...covalent post translational modifications include all of them from ...the post ...
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Event Extraction for Post Translational Modifications
... extracting post-translational modification events from biomedical scientific publica- ...new post-transitional modification event ...400 post-translational modification events ...
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Does Lysozyme Have Post Translational Modifications
... to modifications and post your ...and post your interest is lysozyme peak from sigma chemical ...such modifications have helped handling the lysozyme and post your protein express assay ...
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