B/sub 3/N/sub 4/:B
Decreased bacteria activity on Si<sub>3</sub>N<sub>4</sub> surfaces compared with PEEK or titanium
... (Si 3 N 4 ) – were tested to understand their respective susceptibility to bacterial infection with Staphylococcus epidermidis, Staphlococcus aureus, Pseudomonas aeruginosa, Escherichia coli and ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... Fe 3 O 4 nanoparticles were biocompatible and suitable for biomedi- cal ...Fe 3 O 4 was treated with low temperature intermittent sterilization, and RPMI 1640 culture medium containing 10% ...
10
Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... OH 3 HCl and HAuCl 4 ) were performed during the reaction, and the stirring continued for at least 30 minutes after each ...Fe 3 O 4 @Au composite ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>/DNR magnetic nanoparticles in the treatment of hematologic malignancies
... Fe 3 O 4 ...Fe 3 O 4 -MNPs/DNR groups and negative controls (P ...Fe 3 O 4 -MNPs/DNR was ...Fe 3 O 4 -MNPs/ DNR groups were ...Fe 3 O 4 -MNPs/DNR ...
6
NH<sub>4</sub>HCO<sub>3</sub> gas-generating liposomal nanoparticle for photoacoustic imaging in breast cancer
... (NH 4 HCO 3 ) solution, which is safe, effective, inexpensive, and free of side ...NH 4 HCO 3 decomposes to produce CO 2 , which can absorb much of the light energy under laser irradiation ...
11
Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... Fe 3 O 4 -PLGA NP group and the Fe 3 O 4 -PLGA- cRGD NP ...FeCl 3 injury to the abdominal aorta and at 0 min, 10 min, 20 min, 30 min, 1 h, 2 h, and 3 h after injection of the ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... Ferric chloride hexahydrate (FeCl 3 ⋅ 6H 2 O), ferrous chloride tetrahydrate (FeCl 2 ⋅ 4H 2 O), and ammonium hydroxide (25 wt%) were purchased from Fluka (Buchs, Switzerland). D, L-lactide and glycolide were ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... All animals were kept in stress-free, hygienic, and animal- friendly conditions (relative humidity 60% ± 10%, room tem- perature 20 ° C ± 2 ° C, and 12-hour light/dark cycle). Food and water were available ad libitum. ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... 12PE. These results indicated that the administration of MNPs-Fe 3 O 4 did not cause any appar- ent effects on the expression profile of KCNQ 1 in rested or exercised mice cardiac muscle. Our studies ...
8
Daunorubicin-loaded magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> overcome multidrug resistance and induce apoptosis of K562-n/VCR cells <em>in vivo</em>
... concentration was determined with a Bio-Rad protein assay kit (Bio-Rad Laboratories, Hercules, CA, USA) and standardized with bovineserum albumin. A 50 µ g sample of protein was separated on electrophorased SDS-PAGE and ...
8
Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... (Fe 3 O 4 ) nanoparticles and incorporate them into ...Fe 3 O 4 were first synthesized by chemical co-precipitation and then coated with dextran ...Dex/Fe 3 O 4 particles were ...
12
Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... Several management options are available when prostate cancer is diagnosed at an early stage, including watchful waiting, surgery, cryosurgery, radiation therapy, and hormonal therapy. For advanced prostate cancers, ...
10
The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... important role in regulating the body’s immune response. Th1 cells secrete interleukins such as IL-2 and INF- γ , whose main function is to promote cell-mediated immune response; they are involved in proliferation, ...
6
Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... HAuCl 4 solution containing ...in 3% bovine serum albumin and phosphate-buffered solution at 37 ° C for one hour to block excess active groups and nonspecific binding sites on the ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... The procedures for generation and drug loading of TfDMP are shown in Figure 1. By coupling GA with amino- immobilized Fe 3 O 4 @SiO 2 , the surface of the magnetic nanoparticle can be modified with both ...
9
Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Fe 3 O 4 -MNP increased to ...Fe 3 O 4 -MNP- DNR-5-BrTet the temperature increased to ...Fe 3 O 4 -MNP throughout the ...Fe 3 O 4 -MNP or Fe 3 O 4 ...
9
Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... phase were cultured in 96-well flat-bottomed plates in a triplicate pattern and treated with different concentrations of ART, MNPs-Fe 3 O 4 , or the copolymer of ART with MNPs- Fe 3 O 4 in the ...
8
The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... Mice were randomly assigned to one of four groups (n = 10 per group). The doses of 5.14 mg/kg (low dose group), 20.7 mg/kg (medium dose group), and 51.4 mg/kg (high dose group) Fe 3 O 4 -MNPs, were ...
7
Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... different pH levels which are similar to the pH of the stomach and the pH of the blood. Generally, the pH of the stomach varies from 1–2 to 4–5. After eating, the stomach releases proteases and hydrochloric acid ...
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Pharmacokinetic parameters and tissue distribution of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles in mice
... day 3 after ...day 3, and thereafter decreased ...Fe 3 O 4 MNPs were higher in the liver and spleen than those in other ...day 3 after dosing, indicating that the liver and spleen were ...
6