B-translocation gene 2 (BTG2)
p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient derived xenograft (PDX) models of triple negative breast cancer
... [16]. Gene expression profiling and application of the PAM50 subtype-based predictor categorized WU- BC3 as nonbasal TNBC that clustered most closely with the HER2-E subtype ...
16
B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells
... that BTG2-induced MnSOD expression might be one of the early events of tumor suppression by maintaining the integrity of ...expressed BTG2 was rapidly translocated to mitochondria in response to H 2 ...
14
A molecular signature of dormancy in CD34+CD38 acute myeloid leukaemia cells
... beta 2 microglobulin; BM: bone marrow; BTG2: B cell translocation gene 2; CDKN2B: cyclin-dependent kinase inhibitor 2B; CEBPA: CCAT enhancer binding protein alpha; CSF2RB: colony ...
14
MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2
... The B-cell translocation gene 2 (BTG2) has been implicated in gastric ...and BTG2 in gastric cancer has not been ...that BTG2 was a direct and functional target of ...
12
Gene expression profiles of aralkylamine n-acetyltransferase, b-cell translocation gene-2 and fatty acid synthase in pasture-based primiparous Holstein-Friesian dairy cows supplemented with crude degummed canola oil
... the gene expression patterns of Aralkylamine N-acetyltransferase (AANAT), B-cell translocation gene-2 (BTG2) and Fatty Acid Synthase (FASN) genes in response to incremental ...
10
<p>New Isatin–Indole Conjugates: Synthesis, Characterization, and a Plausible Mechanism of Their in vitro Antiproliferative Activity</p>
... of B cell translocation gene 1, cell cycle-associated proteins (cyclin B1, cyclin D1, and phos- phorylated cyclin-dependent kinase 1), and a pro-apoptotic protein (Bcl-2-associated X protein ...
13
Kaposi's Sarcoma-Associated Herpesvirus-Induced Angiogenin Plays Roles in Latency via the Phospholipase Cγ Pathway: Blocking Angiogenin Inhibits Latent Gene Expression and Induces the Lytic Cycle
... nuclear translocation, and LANA-1 expression, there is evidence for the possibility of additional factors in these interlinked ...latent gene generated from a common promoter and message coding for LANA-1, ...
20
Effects of Genomic Length on Translocation of Hepatitis B Virus Polymerase-Linked Oligomer
... lacZ gene sequence were inserted into the XhoI site at nt 37 on the HBV genome to generate mutants X200, X400, X600, X825, X1021, and ...lanes 2 to ...
9
Kaposi's Sarcoma-Associated Herpesvirus-Positive Primary Effusion Lymphoma Tumor Formation in NOD/SCID Mice Is Inhibited by Neomycin and Neamine Blocking Angiogenin's Nuclear Translocation
... nuclear translocation significantly decreased the pathol- ogy of BCBL-1-induced tumors in NOD/SCID ...development 2 months postinjection. (B) Neomycin or neamine treatment of BCBL-1-injected mice ...
15
Steroid receptor coactivator 3 inhibits hepatitis B virus gene expression through activating Akt signaling to prevent HNF4α nuclear translocation
... Total RNA was isolated with Trizol reagent (Invitrogen) according to the manufacturer’s instructions. The cDNA was synthesized from 2 μg of total RNA using MMLV transcriptase (ToYoBo, Shanghai, China) with random ...
9
Renal Cell Carcinoma Associated with Xp11 2 Translocation/TFE3 Gene Fusion: A Case Report with Immunohistochemical and Cytological Features
... Figure 2(A)) and a positron emission tomography (PET)-CT scan (Figure 2(B)) showed a large mass lesion (78 × 73 × 112 mm) with calcification in the right kidney, compressing the vena ca- va inferior ...
7
A t(3;8) chromosomal translocation associated with hepatitis B virus intergration involves the carboxypeptidase N locus.
... N gene, whose localization in the human genome was not known, to 8p22-23, close to the HBV integration site ...human b -globin gene cluster on chromosome 11, which contains two nonfunctional ...
5
Antigen receptor genes as molecular markers of lymphoid neoplasms
... The normal Bcl-2 gene is highly transcribed at a pre-B cell stage of development when this translocation occurs.. The RNA remains elevated in t 14; 18 bearing mature B cell neoplasms in [r] ...
6
Transcriptome and Functional Analysis of Mating in the Basidiomycete Schizophyllum commune
... and B (25, ...the B loci code for multiallelic pheromone receptors and phero- mones (55, 63, ...and B pathways can be activated by the combination of different allelic specificities in at least one ...
19
Antiviral Activity of Trappin-2 and Elafin In Vitro and In Vivo against Genital Herpes
... for 2 h and, after repeated washes, cultured for an additional 24 ...(A, B) or ANOVA with Tukey’s post hoc test (C, D), with significance indicated in ...
13
Original Article Plexiform fibromyxoma of the stomach a clinicopathological study of 10 cases
... Grossly, all tumors showed a multi-nodular sub- mucosal or intermuscular mass, with a whitish to brownish or reddish cut surface [2]. Mic- roscopic examination was characterized by plexiform or multiple nodular ...
8
Aphid Colonization Affects Potato Root Exudate Composition and the Hatching of a Soil Borne Pathogen
... In this study, we investigated the possible indirect effect that aphids may have on cyst nematodes via root exudate. Hatching of G. pallida was significantly reduced when cysts were incubated in PRE from potato plants ...
10
THE POSITION OF ru-2 AND qv WITH RESPECT TO THE FLECKED TRANSLOCATION IN THE MOUSE
... However, all the dark-eyed animals were wild type at weaning for the ruby phenotype whereas the ruby-eyed animals were either homozygous p ru-2 or some females showed a mos[r] ...
16
Germinal center reentries of BCL2 overexpressing B cells drive follicular lymphoma progression
... memory B cell response dynamics has provided new perspectives on the understanding of the early steps governing B cell lymphomagenesis, in particular those originating from GC B cells ...GC B ...
16
The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4 Not nuclease module
... His-tagged BTG2, whose interaction with Caf1 is well characterised (Figure 1A, 1B) ...trimeric BTG2-Caf1-Ccr4b and dimeric BTG2-Caf1 complexes were obtained (Figure 1C, ...
21