B16 Melanoma
Synthesis, Characterization and Evaluation of Anticancer Activity of Nanoresveratrol in B16 Melanoma Cell Line
... a B16 murine melanoma cell ...in B16 melanoma more efficiently as compared to resveratrol alone and 5 ...of B16 cells is indicative of apoptosis and shows that the anti-cancer effect of ...
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An embryo-specific expressing TGF-β family protein, growth-differentiation factor 3 (GDF3), augments progression of B16 melanoma
... of B16 melanoma GDF3 is a member of TGF- b super family which is expressed in ES cells and in several human tumor ...of B16-F1 cells and cloned into the pEF-BOS expression ...in B16- F1 and ...
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Pattern of expression of immune- and stroma-associated genes in blood of mice with experimental B16 melanoma
... injected B16 melanoma ...experimental melanoma in comparison with the control ...experimental melanoma could be used for non-invasive detection of melanoma cell ...
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Cathepsin L increases invasion and migration of B16 melanoma
... to melanoma cell invasion, other properties of melanoma cells such as migration, adhesion and proliferation have not been well ...in B16 melanoma ...to melanoma cell invasion, ...
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Melanogenesis Inhibitory Activity of Rhododendron Weyrichii in Mouse B16 Melanoma Cells
... Next, we explored the effects of the RW-H and RW-E extracts on a -MSH-induced melanin synthesis and tyrosinase activity. As shown in Fig. 3, cells treated with a -MSH alone had markedly increased melanin content compared ...
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Journal of Applied Pharmaceutical Science
... In continuing to search new materials for skin whitening agent from natural resources, we have focused on plants used by Dayak tribe (native people in East Kalimantan, Indonesia) for skin care treatment. The ethanol ...
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Induction of tumor inhibitory anti angiogenic response through immunization with interferon Gamma primed placental endothelial cells: ValloVax™
... of B16 melanoma, 4 T1 mammary carcinoma, and Lewis Lung Carcinoma (LLC), followed by administration of control saline, control placental endothelial cells, and interferon gamma primed endothelial cells ...
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Effects of Myrica esculenta Bark Extracts on Melanin Biosynthesis
... production, B16 melanoma cells were cultured in the presence of Myrica esculenta bark ...mouse B16 melanoma cells underwent differentiation characterized by increased melanin ...in B16 ...
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Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines
... The altered sugar expression pattern obtained after incu- bation with NeuGc-rich BSM or purified NeuGc resulted in promotion of the malignant phenotype. Preincubation with BSM or NeuGc increased the metastatic ability of ...
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Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects
... The extra- cellular signal-regulated kinase (ERK) signaling pathway induces the inhibition of melanin synthesis in mouse B16 melanoma cells [6].. The activation of ERK leads to phosphory[r] ...
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Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector
... MCF10A were from ATCC; MCF10A cells expressing PIK3CA were kindly provided by Dr. T. Waldmann. MCF10A cells were cultivated in Dulbecco’s modified Eagle’s medium-F12 medium supplemented with 5% horse serum, ...
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A characterization of four B16 murine melanoma cell sublines molecular fingerprint and proliferation behavior
... relevant: B16 F10 is a high metastatic cell line [17,50] and the data from this study show that in the same conditions (number of cells/FCS concen- tration) among the tested cell lines B16F10 presents the highest ...
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Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity
... stable B16 melanoma cell ...of B16 melanoma cells were prepared expressing wild-type or mutant forms of TM, using the V pREP4 to achieve ...in melanoma subclones (a and b) and in ...
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TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma
... 1119 (Sigma) gradient, and then stained for analysis by flow cytometry. Intra-tumoral ratios of CD8 T cells ver- sus FoxP3 + Tregs were significantly increased by the sys- temic CTLA-4 blockade alone or with ...
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Notch1 signaling in melanoma cells promoted tumor-induced immunosuppression via upregulation of TGF-β1
... Methods: Melanoma cell line B16 cells were transfected by lentivirus containing mouse Notch1 gene or Notch1 shRNA to generate B16 cell line that highly or lowly expressed ...murine B16 ...
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Phytochemical capacity of Nitraria retusa leaves extracts inhibiting growth of melanoma cells and enhancing melanogenesis of B16F10 melanoma
... The typical DNA fragmentation pattern which is con- sidered as the hallmark of apoptosis was observed in B16-F10 cells treated with the Chl and EA extracts. As far as the extracts of N.retusa tested in the present ...
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Antitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX) on B16-F10 melanoma
... on B16-F10 melanoma in vitro and in ...in B16-F10 melanoma ...in B16-F10 tumor-bearing ...into B16-F10 cells faster than ...of B16-F10 tumors compared with the SSL-CLA-PTX ...
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Systemically administered liposome encapsulated Ad PEDF potentiates the anti cancer effects in mouse lung metastasis melanoma
... for B16-F10 melan- oma ...infected B16-F10 melanoma cells, deficiency of CAR [32] (data not ...in B16-F10 melanoma ...in B16-F10 melanoma cells transfected by the Ad-PEDF/ ...
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MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells
... It is usually technically cumbersome to generate a stable tumor cell line from primary tumors. This is a major technical limitation for the use of self-gene modified irradiated cell-based vaccines in the clinic (e.g. ...
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Tumor-associated macrophages: an accomplice in solid tumor progression
... promotes melanoma resistance to MAPK pathway inhibitors through nuclear factor κB (NF-κB) dependent expression of the microphthal- mia transcription factor (MITF) ...
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