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bactericidal/permeability increasing protein

Importance of the residue 190 on bactericidal activity of the bactericidal/permeability-increasing protein 5

Importance of the residue 190 on bactericidal activity of the bactericidal/permeability-increasing protein 5

... The bactericidal/permeability-increasing protein (BPI) with bactericidal and endotoxin-neutralizing activity is of considerable interest in clinical ...the bactericidal activity ...

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Impaired Innate Immunity in the Newborn: Newborn Neutrophils Are Deficient in Bactericidal/Permeability-Increasing Protein

Impaired Innate Immunity in the Newborn: Newborn Neutrophils Are Deficient in Bactericidal/Permeability-Increasing Protein

... 55-kDa bactericidal/permeability-increasing protein (BPI), which binds with high affinity to bacterial lipo- polysaccharides and kills Gram-negative ...

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Human bactericidal/permeability increasing protein and a recombinant NH2 terminal fragment cause killing of serum resistant gram negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria

Human bactericidal/permeability increasing protein and a recombinant NH2 terminal fragment cause killing of serum resistant gram negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria

... The bactericidal/permeability-increasing protein (BPI) of neutrophils and BPI fragments neutralize the effects of isolated Gram-negative bacterial lipopolysaccharides both in vitro and in ...

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Extracellular accumulation of potently microbicidal bactericidal/permeability increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate

Extracellular accumulation of potently microbicidal bactericidal/permeability increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate

... antibacterial activity of AF increases during the first 12 h after injection of glycogen in parallel with the influx of PMN. At maximum, > 99% of 10(7) encapsulated Escherichia coli and Staphylococcus aureus are ...

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Role of Charge and Hydrophobic Interactions in the Action of Bactericidal/Permeability increasing Protein of Neutrophils on Gram negative Bacteria

Role of Charge and Hydrophobic Interactions in the Action of Bactericidal/Permeability increasing Protein of Neutrophils on Gram negative Bacteria

... cationic bactericidal/permeability-increasing protein (BPI) from neutrophils on susceptible gram- negative bacteria requires saturation binding to negatively charged surface sites (Weiss, ...

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Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli

Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli

... increase in outer membrane permeability. Moreover, addition of serum albumin after BPI results in growth resumption without displacement of bound BPI and without (early) repair of the envelope alterations. These ...

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Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli

Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli

... the bactericidal/permeability-increasing protein (BPI), two 15-kD species (p15s), and the two most potent (cationic) defensin species (neutrophil peptides [NP] -1 and ...

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Killing of gram negative bacteria by polymorphonuclear leukocytes: role of an O2 independent bactericidal system

Killing of gram negative bacteria by polymorphonuclear leukocytes: role of an O2 independent bactericidal system

... cationic bactericidal/permeability-increasing protein (BPI) present in both rabbit and human polymorphonuclear leukocytes is the principal O2- independent bactericidal agent of these ...

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Changes in Endotoxin-Binding Proteins during Major Elective Surgery: Important Role for Soluble CD14 in Regulation of Biological Activity of Systemic Endotoxin

Changes in Endotoxin-Binding Proteins during Major Elective Surgery: Important Role for Soluble CD14 in Regulation of Biological Activity of Systemic Endotoxin

... lipopolysaccharide-binding protein, and bactericidal/permeability-increasing protein (BPI) were determined in 40 patients 6 h prior to skin incision for major abdominal ...

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Antibiotic proteins of human neutrophils

Antibiotic proteins of human neutrophils

... Abbreviations used in this paper: BP, bactericidal protein; BPI, bactericidal/permeability increasing protein; CAP37, cationic antimicrobial protein of M, 37,000 D; CAP57, cationic antim[r] ...

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Multiple gene to gene interactions in children with sepsis: a combination of five gene variants predicts outcome of life threatening sepsis

Multiple gene to gene interactions in children with sepsis: a combination of five gene variants predicts outcome of life threatening sepsis

... and bactericidal permeability increasing protein (BPI) polymorphisms are associated with different outcomes of sepsis ...lipopolysaccharide-binding protein (LBP, OMIM ...phase ...

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Bactericidal Permeability Increasing Proteins Shape Host Microbe Interactions

Bactericidal Permeability Increasing Proteins Shape Host Microbe Interactions

... Analyses of the genomes and transcriptomes of mollusks have revealed encoded and expressed antimicrobial peptides and proteins in those epithelial surfaces that are likely to actively shape the communities of microbes ...

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A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models

A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models

... tissue permeability (Figure 5 in Paper I), here we discuss only the effect of tissue permeability for reactive flows without ...Ideal permeability tissue model at ...paper, increasing the ...

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Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae

Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae

... covalently to the antibody molecule. Finally, 125I-GC constituents with covalently bound C3 were affinity purified on Sepharose bearing antibodies to C3 and identified by sodium dodecyl sulfate polyacrylamide gel ...

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Increased Vascular permeability produced by human platelet granule cationic extract

Increased Vascular permeability produced by human platelet granule cationic extract

... inactivator. Permeability-enhancing activity was blocked by prior treatment of challenged animals with ...granule protein extract possessed potent mastocytolytic ...a permeability-enhancing effect by ...

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Evaluation of hybrid membrane bioreactor (MBR) for palm oil mill effluent (POME) treatment

Evaluation of hybrid membrane bioreactor (MBR) for palm oil mill effluent (POME) treatment

... of permeability after cleansing process for long-term ...days. Permeability declined from 37 LMH/ bar to 24 LMH at day 7 and was slightly constant until day ...kept increasing up to ...the ...

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Viperatoxin-II : a novel viper venom protein as an effective bactericidal agent

Viperatoxin-II : a novel viper venom protein as an effective bactericidal agent

... Several proteins and polypeptides of reptiles have common cytolytic properties, and these cytolysins provide an offensive armament for the animal defense. In this study, cell survival decreased with the increasing ...

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Viscoelastic Effects on Unsteady Two Dimensional and Mass Transfer of a Viscoelastic Fluid in a Porous Channel with Radiative Heat Transfer

Viscoelastic Effects on Unsteady Two Dimensional and Mass Transfer of a Viscoelastic Fluid in a Porous Channel with Radiative Heat Transfer

... The purpose of this study is to bring out the effects of viscoelastic parameter  on the governing flow. The effects of viscoelastic parameter on the fluctuation of axial velocity distribution, shear stress, heat ...

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Surfactant proteins A and D inhibit the growth of Gram negative bacteria by increasing membrane permeability

Surfactant proteins A and D inhibit the growth of Gram negative bacteria by increasing membrane permeability

... mannose-binding protein A (4), including N-terminal collagen-like regions and C-ter- minal C-type lectin carbohydrate recognition domains (CRDs), which identified them as pattern recognition receptors and members ...

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Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability

Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability

... Furthermore, by measuring the zeta potential of the cell membrane, we found that the surface charge of the melanoma cells was typically negative ( - 18.2 ± 0.9 mV), as shown in Figure[r] ...

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