BALB/c mouse model
Discovery of common marburgvirus protective epitopes in a BALB/c mouse model
... antibody-mediated protection, it seemed highly likely that cellular immunity contributes to the host's protective immune response against MARV. To determine the importance of T-cell responses during MARV infection, we ...
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Galantamine Effect on Tularemia Pathogenesis in a BALB/c Mouse Model
... Background: Galantamine is a drug used for the treatment of Alzheimer’s disease and some other cognitive disorders. It is an inhibitor of acetylcholinesterase; however, interaction with nicotinic acetylcholine receptors ...
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Molecular basis of Escherichia coli colonization of the upper urinary tract in BALB/c mice Gal Gal pili immunization prevents Escherichia coli pyelonephritis in the BALB/c mouse model of human pyelonephritis
... infection model was established in the 16-wk-old female BALB/c mouse to compare the pathogenic significance of MS and Gal-Gal pili and their efficacy as vaccines for the prevention of ...
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An immunocompromised BALB/c mouse model for respiratory syncytial virus infection
... (A) BAL cell differential of RSV-infected mice. Mice were treated with cyclophosphamide (CYP) or vehicle 5 days before infection with RSV. Animals were sacrificed on day 4 postinfection and BAL was performed. Following ...
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Mechanisms of resistance and susceptibility to experimental visceral leishmaniosis: BALB/c mouse versus syrian hamster model
... problem. BALB/c mice and Syrian hamsters are the most widely used experimental ...the BALB/c mouse model have underscored differences between the liver and spleen in the course ...
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Differential Histopathology and Chemokine Gene Expression in Lung Tissues following Respiratory Syncytial Virus (RSV) Challenge of Formalin-Inactivated RSV- or BBG2Na-Immunized Mice
... which BALB/c mice were immunized with several different doses of FI-RSV or BBG2Na adjuvanted with aluminum salts, followed by challenge with RSV and sacrifice at several time points ...The ...
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Lactobacillus paracasei feeding improves the control of secondary experimental meningococcal infection in flu infected mice
... a BALB/c mouse model, most likely through the modula- tion of the immune response in the respiratory system ...murine model of sequen- tial flu-meningococcal infection to explore the ...
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Murine Cytomegalovirus Major Immediate-Early Enhancer Region Operating as a Genetic Switch in Bidirectional Gene Pair Transcription
... The BALB/c mouse model of syngeneic bone marrow transplantation and infection with the mCMV wild-type Smith (ATCC VR-194) strain was employed to establish viral latency in the lungs of ...
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Recombinant Parainfluenza Virus 5 Vaccine Encoding the Influenza Virus Hemagglutinin Protects against H5N1 Highly Pathogenic Avian Influenza Virus Infection following Intranasal or Intramuscular Vaccination of BALB/c Mice
... the BALB/c mouse model, a single intramuscular or intranasal immuni- zation with a live rPIV5-H5 (ZL46) rapidly induced robust neutralizing serum antibody responses and protected against HPAI ...
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Pyruvate kinase is necessary for Brucella abortus full virulence in BALB/c mouse
... Brucellosis, caused by a facultative intracellular pathogen Brucella, is one of the most prevalent zoonosis worldwide. Host infection relies on several uncanonical virulence factors. A recent research hotpot is the links ...
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Original Article The Effect of Different Doses of Cigarette Smoke in a Mouse Lung Tumor Model
... in Balb/c mice (data not published), and we did not find in the literature any successful experimental model of lung carcinogenesis in Balb/c mice or any information about how much ...
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Alterations in the self renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis
... in Balb/c IL1 ra-/- mice, who pro- gressed to develop RA-like disease and not in C57BL6 IL1ra-/-, which have been shown not to develop RA-like arthritis, suggesting an association of these abnormalities ...
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Human metapneumovirus induces more severe disease and stronger innate immune response in BALB/c mice as compared with respiratory syncytial virus
... the mouse and in the cotton rat model [13,14,16], showed uniphasic growth kinetics, more consistent with our results and similar to what can be observed after RSV infection ...
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Original Article Impact of sex hormone on small cell lung carcinoma xenograft model in nude mouse
... xenograft model in nude ...36 BALB/c-nu nude mice were divided into 3 experimental groups and were respectively inoculated suspension of MSCLX-07 cells which were stimulated with different sex ...
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In vivo activity of plant based interleukin 12 in the lung of Balb/c mouse
... Here we describe the in vivo activity of a single-chain IL- 12 expressed in an edible crop, the tomato. At present, the crop that has been used the most for production of immunomodulatory molecules is tobacco. This ...
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In Vivo Competence of Murine Cytomegalovirus under the Control of the Human Cytomegalovirus Major Immediate-Early Enhancer in the Establishment of Latency and Reactivation
... neonate mouse model and established conditions of infection that mostly reproduce the extent of viral replication in different organs and parallel latency/reactivation properties of parental ...per ...
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Establishment and Characterization of a Lethal Mouse Model for the Angola Strain of Marburg Virus
... There is a need to develop MARV models for immunocompe- tent small animals using variants that are antigenically distinct from RAVV. This is important for facilitating the development of MARV vaccines or therapeutics so ...
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Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model
... neosporosis mouse model for cerebral infection comprising Balb/c mice experimentally infected with the virulent isolate Nc‑Spain7, the three anti‑malarial compounds failed to exhibit any ...
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Thymus involution induced by mouse hepatitis virus A59 in BALB/c mice.
... Mouse hepatitis virus A59 (MHV-A59) infection of adult BALB/c mice induced a severe, transient atrophy of the thymus. The effect was maximal at 1 week after infection, and thymuses returned to normal ...
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Quantitative Changes in Gimap3 and Gimap5 Expression Modify Mitochondrial DNA Segregation in Mice
... Cells or tissue samples were solubilized in phosphate buffered saline, 1% dodecyl-maltoside, 1 mM PMSF (phenylmethyl- sulfonyl fluoride), complete protease inhibitor (Roche). Pro- tein concentrations were measured by the ...
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