Barrett’s esophagus
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
... the Barrett’ s esophagus-associated SNPs at 16q24 were similar in esophageal adenocarcinoma, we used the combined Barrett’ s esophagus and cancer data to identify other SNPs ...
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Changes of microRNAs-192, 196a and 203 correlate with Barrett's esophagus diagnosis and its progression compared to normal healthy individuals
... Therefore the aim of this study was to identify a com- bination of selected microRNAs levels of which (com- pared to normal healthy individuals) would definitely characterize a patient with Barrett ’ s ...
7
Length of Barrett’s segment predicts failure of eradication in radiofrequency ablation for Barrett’s esophagus: a retrospective cohort study
... After the study was reviewed and approved by the Uni- versity of Alabama at Birmingham Institutional Review Board (IRB), a retrospective review of consecutive pa- tients undergoing RFA between December 2009–Febru- ary ...
8
Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma
... The Barrett’ s cases were identified at endoscopy with a confirmed histopathological diagnosis of intestinal metaplasia from the UK Barrett’ s Oesophagus Gene Study as previously ...to ...
17
A neuroendocrine carcinoma with a well-differentiated adenocarcinoma component arising in Barrett’s esophagus: a case report and literature review
... The World Health Organization’s 2010 cancer classifica- tion considered NECs as a subgroup of neuroendocrine neoplasms [7]. In brief, neuroendocrine neoplasms can be categorized into three grade-based groups, and among ...
6
Barrett’s esophagus and the risk of obstructive sleep apnea: a case–control study
... Barrett’s esophagus and scoring at high risk for OSA com- pared with the COL group was no longer statistically sig- ...striking. Barrett’ s esophagus patients may be more likely to have ...
9
Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma
... (A) Esophagus of healthy controls is lined by a stratified squamous epithelium and is negative for PXR ...(C) Barrett ’ s epithelium is characterized by a single layer of columnar epithelium with the ...
9
Association between obesity and Barrett’s esophagus in a Japanese population: a hospital-based, cross-sectional study
... In Japan, the GEJ is defined as the distal limit of the lower esophageal palisade vessels [21], but in the West the GEJ is defined as the proximal margin or upper end of the gastric folds (Prague C&M criteria) [16]. ...
8
High expression of RNA-binding motif protein 3 in esophageal and gastric adenocarcinoma correlates with intestinal metaplasia-associated tumours and independently predicts a reduced risk of recurrence and death
... Tissue microarrays (TMAs) were constructed using a semi-automated arraying device (TMArrayer, Pathology Devices, Westminister, MD, USA). Duplicate tissue cores (1 mm) were obtained from viable, non-necrotic areas from ...
11
Detection of fluorescent organic nanoparticles by confocal laser endomicroscopy in a rat model of Barrett’s esophageal adenocarcinoma
... Notes: (A) Endoscopic view of normal mucosa which shows a smooth and white epithelium with a distinct vascular pattern. Histology of normal esophageal mucosa: normal squamous epithelium layering on thin lamina propria ...
13
Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett’s epithelium
... Barrett’s esophagus (BE) is a specialized columnar intes- tinal metaplasia containing goblet cells that replaces the native esophageal squamous mucosa in individuals with long-standing gastroesophageal reflux ...
8
Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma
... Methods: Barrett ’ s esophagus patients with low or high-grade dysplasia ( n = 9) and EAC patients (Stage I/II) eligible for treatment were enrolled ( n = ...
5
Activation of EGFR-DNA-PKcs pathway by IGFBP2 protects esophageal adenocarcinoma cells from acidic bile salts-induced DNA damage
... Three immortalized cell lines originated from Barrett’s esophagus, BAR10T (kindly provided by Dr. Rhonda Souza), CPA and CPB (ATCC, Manassas, VA, USA), were cultured with DMEM/F12 (GIBCO, New York, NY, USA), ...
14
Role of XPC, XPD, XRCC1, GSTP genetic polymorphisms and Barrett’s esophagus in a cohort of Italian subjects. A neural network analysis
... All the above data prompted us to investigate the XPC, XPD, XRCC1, and GSTP genetic polymorphisms in relation to Barrett’s esophagus in a cohort of Italian subjects. We report here results from an exploratory ...
8
Optimal management of Barrett's esophagus: pharmacologic, endoscopic, and surgical interventions
... Barrett’s esophagus requires acid suppression and endoscopic ...Barrett’s esophagus, treatment with a PPI may decrease acid exposure and delay the progression to ...
12
Clinicopathologic characteristics of high expression of Bmi-1 in esophageal adenocarcinoma and squamous cell carcinoma
... dysplasia, Barrett’ s esophagus and columnar cell ...Barrett’s esophagus (22%), low- (45%) and high-grade dysplasia (43%) and adenocarcinoma ...and Barrett’ s esophagus ...
10
<p>A Cost-Effectiveness Analysis Of An Adenocarcinoma Risk Prediction Multi-Biomarker Assay For Patients With Barrett’s Esophagus</p>
... A newly developed risk prediction multi-biomarker assay (TissueCypher ® Barrett ’ s Esophagus Assay, Cernostics, Inc., Pittsburgh, PA, USA, more details of the Assay in Appendix 1), has been shown to ...
13
Metastatic melanoma in an esophagus demonstrating Barrett esophagus with high grade dysplasia
... with Barrett ’ s esophagus with high grade dysplasia and presented to our institution for ...Barrett esophagus. Microscopic examination demonstrated extensive Barrett ...
5
A clinical risk prediction model for Barrett esophagus.
... Almost all cases of EAC are thought to arise from underlying Barrett’s esophagus (BE), progressing through low to high grade dysplasia (6); however the risk of progressing from BE to EAC is unclear. Initial ...
31
Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer
... normal esophagus, and the type II microbiome, in which Gram-negative anaerobes predominate, which is associ- ated with Barrett’ s esophagus (BE) and esophagitis ...Barrett’s esophagus, ...
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