BCC, basal cell carcinoma
Comparison of free lateral and deep margins of basal cell carcinoma (bcc) by the means of two staining methods: hematoxylin and eosin stain (h&e) and immunohistochemistry (ihc)
... of BCC that there is a similar negative pathologic margins between 2,3,4 and 5mm surgical margin while they have significantly different relative risk of ...
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Health related quality of life in patients with actinic keratosis – an observational study of patients treated in dermatology specialist care in Denmark
... AK: Actinic keratosis; AKQoL: Actinic keratosis quality of life questionnaire; BCC: Basal cell carcinoma; CRF: Case report form; DLQI: Dermatology life quality index; EQ-5D-5 L: EuroQoL [r] ...
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Tropomyosin Receptor Antagonism in Cylindromatosis (TRAC), an early phase trial of a topical tropomyosin kinase inhibitor as a treatment for inherited CYLD defective skin tumours: study protocol for a randomised controlled trial
... reaction; BCC: Basal cell carcinoma; BCL2: B-cell lymphoma 2; CIOMS: Council for International Organisations of Medical Sciences; CTA: Clinical Trial Agreement; CYLD : Cylindromatosis ...
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The cylindromatosis (CYLD) gene and head and neck tumorigenesis
... low-grade; BCC, Basal cell carcinoma; Bcl-3, B-cell lymphoma 3; BSS, Brooke-Spiegler Syndrome; CAP350, Centrosome-Associated Protein 350; cIAP1/2, Cellular inhibitor of apoptosis 1 and ...
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Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma
... patients aged ≥65 and <65 years, respectively, compared with a prevalence of 27% and 25%, respectively) [9]. In this analysis, the safety profile of vismodegib in patients aged ≥65 years appeared to be similar to that ...
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Resistance to anti-PD-1-based immunotherapy in basal cell carcinoma: a case report and review of the literature
... a BCC tumor is infiltrated by a higher number of negative regulatory im- mune cells which might also impair the activity of CD8+/ Granzyme B+ T cells [51], undermining the efficacy of PD-1 ...In BCC Walter ...
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Basal Cell Carcinoma of the Skin to Tirana-Albania
... Basal cell carcinoma (BCC) is the most frequent epithelial tumor of the skin, characterized by a local infiltrative growth in contrast to a very rarely ...a BCC as giant. Only the 1% of ...
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Safety and efficacy of vismodegib in patients with basal cell carcinoma nevus syndrome: pooled analysis of two trials
... (ERIVANCE BCC), vismodegib demonstrated an overall response rate (ORR) of 43 % in patients with laBCC and 30 % in patients with mBCC by independent review ...existing BCC lesions and prevented development ...
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A highlight on Sonic hedgehog pathway
... The first clinical trial, targeting Smo and so using Shh pathway inhibitor as therapy, considered several patients with recurrent or metastatic basal cell carcinoma (BCC). At that time, a ...
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Moderate- to low-risk variant alleles of cutaneous malignancies and nevi: lessons from genome-wide association studies
... as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), have become increasingly common in recent ...(excluding BCC and SCC) ...[2]. BCC is the most common ...
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Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened
... An essential role for Hedgehog (Hh) signaling in human cancer has been established beyond doubt. At present, targeting Hh signaling has mainly been investigated with SMO inhibitors. Unfortunately, resistance against ...
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Nevoid basal cell carcinoma syndrome (Gorlin syndrome)
... the basal cell cancers become aggressive and invade locally ...polypoid basal cell carcino- mas (PBCC) in the perineum, leading to the recommenda- tion that the perineum, perianal, and genital ...
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Squamous cell carcinoma developed on neglected, mistreated and delayed diagnosed chronic venous leg ulcer
... squamous cell carcinoma (SCC) with particularly aggressive ...and basal cell carcinoma (BCC) excision and chronic venous insuffi ciency showing for about three years a ulcerated ...
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... cyst, Basal Cell Carcinoma (BCC), Squamous Cell Carcinoma (SCC), melanoma, sebaceous carcinoma, merkel cell tumour, pilomatrixoma, granular cell tumour, ...
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Skin cancer diagnosis and surgical management in general practice
... study BCC and SCC were differentiated, and all in situ malignancies were ...of basal cell carcinoma (BCC) were ...squamous cell carcinoma (SCC) were ...of BCC were ...
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Keratotic and Pigmented Basal Cell Carcinoma
... of basal cell carcinomas and is most common over the skin of the ...meningitis. BCC may have solid, cystic, adenoid, keratotic, pigmented, infiltrating and sclerosing ...mented BCC contains ...
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Basal cell carcinoma: 10 year experience with electrochemotherapy
... the cell effectively ...for BCC patients (NICE interventional procedure guidance [IPG478], pub- lished date: February ...Although BCC is by far the most frequent skin cancer, clinical experience with ...
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Basal cell carcinoma-a case report and review
... Early BCC appear as small, translucent or pearly, with raised areas in which dilated vessels can be seen ...Typical BCC are indolent with slow progression, but if neglected can become locally destructive ...
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Frequent detection of human polyomavirus 6 in keratoacanthomas
... squamous cell carcinoma (SCC) was shown in the general population and im- munosuppressed organ transplant recipients ...squamous cell carcinoma (SCC), but not basal cell ...
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Human Papillomaviruses, p16INK4a and Akt expression in basal cell carcinoma
... squamous cell carcinoma ...squamous cell carcinoma ...squamous cell carci- nomas of non-EV patients [14,15] but few data exist on basal cell carcinoma (BCC), ...
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