bcl-2 and p53
LEVELS BCL-2, P53 IN BLOOD SERUM IN SMOKERS (HEALTHY AND CANCEROUS PATIENTS).
... of p53 and change Bcl-2 ...markers Bcl-2 and p53 proteins in serum and the activity of the antioxidant (AO) enzymes (Cu, Zn superoxide dismutase (SOD), glutathione peroxidase ...
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Original Article Overexpression of microRNA-149 inhibits chondrocyte apoptosis by regulating expression of Bcl-2, Bax, and p53
... To further investigate the possible underlying mechanism of apoptosis induced by overex- pression of miR-149, we analyzed the protein expression levels of Bax, Bcl-2, p-p53, and p-53 after ...
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Expression of Bcl-2 and p53 protein in Stomach Cancer Patients and Association with Clinicopathological Factors
... worldwide. Bcl-2 and p53 appear to be important biomarkers in patients with stomach ...of Bcl-2 and p53 proteins and its association with clinicopathological factors in 67 ...
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Expression of bcl-2 and p53 in bovine cutaneous fibropapillomas
... of bcl-2 and p53 was assessed by immunohistochemistry and Western ...for bcl-2 throughout basal and parabasal layers, with most of cells showing strong cytoplasmic and membrane ...
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Expression Analysis of p53, Ki 67 and bcl 2 in Pre Malignant Lesions of the Cervix
... expression: p53(−), Ki-67(+), bcl-2(−) and p53(−), Ki-67(−), bcl-2(−) was statistically significant when associated with the lesion ...the p53, Ki-67 and bel-2 ...
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4 Nonylphenol induces disruption of spermatogenesis associated with oxidative stress related apoptosis by targeting p53 Bcl 2/Bax Fas/FasL signaling
... every 2 days for 20 consecutive days) by intra-peritoneal ...of Bcl-2/Bax ratios and up-regulation of Fas, FasL and p53 at the protein and mRNA ...function. p53-independent ...
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Expression of caspase-3, p53 and Bcl-2 in generalized aggressive periodontitis
... for p53 (Ready-to-use Ab-5, NeoMarkers, Fremont, CA, USA), Bcl-2 (Ready-to-use Ab-1, NeoMarkers, Fremont, CA, USA), and caspase-3 (Ready-to-use Ab-5, NeoMarkers, Fremont, CA, USA) for 2 hours ...
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Immunohistochemical Detection of P53,bcl-2 and Retinoblastoma Proteins in Primary Mediastinal Large B Cell Lymphoma
... of P53 and bcl-2, accompanied with progressive clinical courses, possibly indicates poor prognosis and suppression of chemotherapy induced apoptosis ...extensive P53 gene mutation and ...
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Immunohistochemical Expression of Ki 67, PCNA, pRb, p16, p53, Bcl 2 and Bax in Esophageal Adenocarcinoma and Barrett’s Associated Dysplasia
... p16, p53, Bcl-2 and Bax was evaluated by immunohistochemistry in archival tissue samples, collected from 15 patients with EAC and 5 patients with BE-associated ...p16, p53, Bcl-2 ...
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Evidence that the p53 negative / Bcl 2 positive phenotype is an independent indicator of good prognosis in colorectal cancer: A tissue microarray study of 460 patients
... prognosis p53(-)/Bcl-2(+) subgroup in earlier stage tumours, in agreement with the findings of Gouissa et al, who demonstrated a trend for the p53(-)/Bcl-2(+) pheno- type to be ...
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Comparison of Expression of p53 and bcl-2 Markers in Oral Lichen Planus and Oral Squamous Cell Carcinoma
... type. Bcl-2 has the potential to discontinue apopto- sis in both the early and final stages of cancer, and the association between the expression of p53 and bcl-2 in pathologic lesions, ...
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The tissue dependent interactions between p53 and Bcl-2 in vivo
... soon became runts (Figure 1A), and succumbed to polycystic kidney disease between the third and eighth week of life. Strikingly, all the double knockout mice (n = 17) exhibited growth retardation with short ears (Figure ...
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Diphenyleneiodonium Inhibits Apoptotic Cell Death of Gastric Epithelial Cells Infected with Helicobacter pylori in a Korean Isolate
... Our study shows that DPI, an inhibitor of NADPH oxi- dase, suppresses H. pylori-induced cell death, hydrogen peroxide production, DNA fragmentation, increase in the ratio of Bax/Bcl-2, and p53 ...
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Clinical and immunohistochemical study of eight cases with thymic carcinoma
... to p53 expres- sion in thymic carcinoma, previous studies had also re- ported similar ...for p53 immunostaining. Tateyama et al[9] also re- ported that p53 gene mutation occurred early in the ...
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Key words
... of p53 might lead to cellular proliferation, and non-malignant fibroma- tosis ...Dysfunctional p53 genes and increases in the expression of Bcl-2 have been associated with higher rates of ...
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Folic Acid Supplementation Ameliorates Inflammation and Apoptosis in Ethanol Induced Gastric Ulceration in Rats
... using avidin for 15 min, and endogenous biotin in tissue were blocked using biotin for another 15 min. Incubation followed, thereafter, with the respective diluted primary antibody viz: p53 and BCl-2 ...
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Pressure shift mediated anoikis of endothelial cells in the flow field in vitro
... protein Bcl-2 in mito- chondrial ...of P53 protein during the first 2h was inducing the growth arrest to reduce the sensitivity of ECs to ...down-regulated P53 expres- sion on the 2h ...
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Evaluation of Apoptotic Genes Expression and Its Protein after Treatment of Cryptorchid Mice
... Bax, Bcl-2 proper, p53 and survivin mRNA and protein were determined after performing the two treatment methods: surgical return of testis into scrotum (Exp1) and transplantation of spermatogonial ...
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<p>microRNA-519d Induces Autophagy and Apoptosis of Human Hepatocellular Carcinoma Cells Through Activation of the AMPK Signaling Pathway via Rab10</p>
... Rab10, p53, mammalian target of rapamycin (mTOR), Bcl-2 asso- ciated X protein (Bax), B-cell lymphoma-2 (Bcl-2), Beclin1, Atg5, and the internal references U6 and glycer- ...
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Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells.
... When the Bcl-2 protein is expressed in HeLa cells during infection by mutant adenovirus deleted in the E1B 19K gene, any alterations in the induction of p53 levels by ElA may be attribut[r] ...
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