beta 2-adrenergic receptors
Protective effects of a glucocorticoid on downregulation of pulmonary beta 2 adrenergic receptors in vivo
... increased beta 1- and beta 2-receptor numbers by 70 and 69% above control, respectively, but did not change their mRNA ...days 2-8) decreased beta 1- and beta 2-receptor ...
9
Mapping of a functional autoimmune epitope on the beta 1 adrenergic receptor in patients with idiopathic dilated cardiomyopathy
... against beta-adrenergic receptors in patients with idiopathic dilated cardiomyopathy were studied using synthetic peptides derived from the predicted sequences of the human ...
7
Endogenous sensitizer of beta-adrenergic receptors (ESBAR) and its analogs (review)
... of beta 1 - and beta 2 -AR propranolol (obzidan) at concentrations of 10-9 -10-6 g/mL dose- dependently partially or completely block the ability of adrenaline (10-7 g / mL) to lower the tone, ...
15
Coregulation of calcium channels and beta adrenergic receptors in cultured chick embryo ventricular cells
... determinations were performed in similar intact cell preparations under identical conditions. 4-h exposure to 1 microM isoproterenol reduced cell surface beta-adrenergic receptor number from 44 +/- 3 to 17 ...
8
The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling mechanisms
... age. Beta-adrenergic blockers appear to have a beneficial clinical effect in cancer ...oxidase. Beta-adrenergic blockers also exert anticancer effects through non-genomic factors, including ...
15
In vivo regulation of beta adrenergic receptors on mononuclear leukocytes and heart Assessment of receptor compartmentation after agonist infusion and acute aortic constriction in guinea pigs
... of beta-adrenergic receptors occurred in the MNL of animals treated in this manner, whereas the number of receptors in the sarcolemmal fraction decreased ...cardiac receptors may result ...
8
Molecular characterization of [beta]2 adrenergic receptor haplotypes
... expressed receptors on cells transfected with each of the three ADRB2 haplotypes; whereas, the Western is not an absolute measure, but a relative protein ...than 2-fold differences in expression); although, ...
81
The Glucose Receptor A DEFECTIVE MECHANISM IN DIABETES MELLITUS DISTINCT FROM THE BETA ADRENERGIC RECEPTOR
... pancreatic beta adrenergic receptors and the implications of this relationship with regards to abnormal insulin secretion in diabetes mellitus, two questions were ...upon beta ...
8
Adrenergic regulation of glycogenolysis in rat liver after cholestasis Modulation of the balance between alpha 1 and beta 2 receptors
... stimulation became predominantly beta adrenergic in cholestatic animals (phenylephrine Ka = 3.7 microM, isoproterenol Ka = 0.06 microM). In normal rats, activation of the enzyme by epinephrine was inhibited ...
12
Identification of beta adrenergic receptors in human lymphocytes by ( ) (3H) alprenolol binding
... cyclase-coupled beta-adrenergic receptors. Binding was rapid (t1/2 less than 30 s) and rapidly reversible (t1/2 less than 3 min) at 37 degrees ...
8
Positive coupling of beta like adrenergic receptors with adenylate cyclase in the cnidarian Renilla koellikeri
... a receptors other than b -adrenergic receptors in the tissues of the sea pansy, possibly through dopaminergic and serotonergic ...8 2 ) ...
16
Beta Adrenergic Receptors of Polymorphonuclear Particulates in Bronchial Asthma
... systemic adrenergic medication (group 2), and 17 asthmatics receiving adrenergic agonists systemically (group ...no adrenergic drugs bound similar amounts of DHA at ...receiving ...
10
Original Article Beta-3 adrenergic receptors could be significant factors for overactive bladder-related symptoms
... above. Beta-ARs mediate relaxation of smooth muscle in the bladder, urethra and prostate, and it appears that the β-3- and β-2-subtypes are important in the human bladder and urethra, respectively ...
8
Direct relationship between mononuclear leukocyte and lung beta adrenergic receptors and apparent reciprocal regulation of extravascular, but not intravascular, alpha and beta adrenergic receptors by the sympathochromaffin system in humans
... between adrenergic receptors on accessible circulating cells and relatively inaccessible extravascular catecholamine target tissues, we measured mononuclear leukocyte (MNL) and lung ...
10
Autoradiographic characterization of beta adrenergic receptors in coronary blood vessels and myocytes in normal and ischemic myocardium of the canine heart
... metoprolol, a beta one selective antagonist, demonstrated a KD of 0.7 X 10(-6) M. For autoradiography, emulsion-coated coverslips were attached to the slides. After exposure, the slides were developed and stained, ...
10
Exercise induced pulmonary vasoconstriction during combined blockade of nitric oxide synthase and beta adrenergic receptors
... We studied the effects of inhibition of nitric oxide (NO) (endothelium-derived relaxation factor) synthase in combination with alpha and beta adrenergic receptor blockade on pulmonary vascular tone during ...
8
Diabetes and beta adrenergic blockage are risk factors for metastatic prostate cancer
... Also, beta-adrenergic signaling has been associated with advanced prostate cancer [25] and beta-blockers have been associated reduced mortality in various tumor types ...unselective ...
6
Characterization and distribution of alpha 2 adrenergic receptors in the human intestinal mucosa
... alpha 2-adrenergic receptor were investigated in the normal mucosa from human intestine by means of radioligand binding, RNase mapping, and measurement of adenylate cyclase ...alpha 2- ...
10
Effects of pressure overload, left ventricular hypertrophy on beta adrenergic receptors, and responsiveness to catecholamines
... dP/dt. beta-adrenergic receptor binding studies with [3H]-dihydroalprenolol ( [3H]DHA) indicated that the density of binding sites was significantly elevated, P less than ...
11
[beta]2-adrenergic receptor modulation of macrophage inflammatory mediator production
... transcriptional regulation of several pro-inflammatory molecules, the mechanisms surrounding TNF-α production are the most studied. In 2000, Farmer and Pugin published a landmark paper describing the molecular basis of ...
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