Bi/sub 2/Fe/sub 4/O/sub 9/
Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... NH 4 OH) introduced by ...a 2 M hydrochloric acid solution and then washed five times with acetone to remove the excess oleic ...NH 4 OH) and 1 g of oleic acid were added to disperse the magnetic ...
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Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
... 60%. Fe 3 O 4 @SiO 2 /PEI, Fe 3 O 4 @SiO 2 / PEI/Sc shRNA, or Fe 3 O 4 @SiO 2 /PEI/VEGF shRNA was incubated with the cells in serum-free ...
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Effects of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combinated with gambogic acid on apoptosis of SMMC-7721 cells
... The Fe 3 O 4 -MNP itself had no obviously inhibitory effect, but it could enhance the effect of GA on proliferation of SMMC-7721 ...with Fe 3 O 4 -MNP was higher than that by GA ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... uncoated, Fe m O n -SiO 2 composite flake-like, and SiO 2 -Fe m O n core-shell IONPs on cell viability, function, and mor- phology were tested 48 h postincubation in human ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... Reagents used in cell culture include albumin solution from bovine serum (Sigma-Aldrich Co.), ascorbic acid (C 6 H 8 O 6 ; Sigma-Aldrich Co.), Dulbecco’s Modified Eagle’s Medium (DMEM; high glucose with l ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... 3 O 4 (1 µ g/mL, 10 µ g/mL, or 100 µ g/mL) for 24 hours in the absence or presence of N-acetylcysteine (NAC; 10 mM) (Sigma-Aldrich Co); NAC was added 3 hours before treatment with MgNPs-Fe 3 O ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... Nanotechnology offers an efficient alternative for cancer diagnostics and tumor target treatment due to the unique properties of nanostructures, such as large surface-to-volume ratio, porous structure, embedded effect, ...
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Inhibitory effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
... As shown in Figure 1A, the polymeric micelles were gener- ated by the hydrophobic interaction of the polyoxyethylene– polyoxypropylene copolymer chain and oleic acid on the surface of iron oxide NPs. The average core ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... and the blots were stained with specific primary antibodies, including anti-bcl-2, anti-bax, anti-survivin, anti-bcl-rambo, anti-active caspase-3, and anti-GAPDH antibodies overnight at 4 ° C. Then, the ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... A 10 mL blood sample was taken from a New Zealand rabbit (male, 2.1 kg), to which 0.5 mL of 20 g/L potassium oxalate was added. Fresh rabbit blood was diluted (dilution ratio 8 mL blood to 10 mL normal saline). Fe ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... daunorubicin, Fe 3 O 4 -MNP, and Fe 3 O 4 -MNP coloaded with daunorubicin and 5-bromotetrandrine (Fe 3 O 4 -MNP-DNR-5-BrTet), with hyperthermia in an ...
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In vitro and in vivo targeting imaging of pancreatic cancer using a Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoprobe modified with anti-mesothelin antibody
... In vitro targeting test was performed by adding fluorescent quantum dots to nanoprobes to observe the cellular adsorption. Results shown in Figure 4 suggest that the red fluorescent dots were more frequently found ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... the Fe 3 O 4 /Au nanocarrier, the ratio of HRP and Ab 2 is the most important factor in the response ...HRP/Ab 2 , and the maxi- mum response is achieved at a ratio of ...HRP/Ab ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... minor modifications. An aqueous solution of doxorubicin 5 mg/5 mL was emulsified in 10 mL dichloromethane, in which 120 mg of the copolymer and 4 mg magnetic nanopar- ticles had been dissolved, using a probe ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... of Fe 3 O 4 (MNPs-Fe 3 O 4 ...3 O 4 dramati- cally enhanced GA-induced cytotoxicity and apoptosis in K562 ...3 O 4 were observed under an optical ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... 3 O 4 ) nanoparticles with appropriate surface modification, which have been widely used experimentally for numerous in vivo applications, such as magnetic resonance imaging, tissue repair, immunoassay, ...
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Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... the Fe 3 O 4 -NPs have spherical morphology and a uniform ...the Fe atoms as a covering material to create steric block, like the common stabilizers and ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... average weights of the three TiO 2 NP groups and three Fe 3 O 4 - TiO 2 NP groups were 399.16 ± 13.56 g, 401.50 ± 16.48 g, 409.80 ± 26.60 g, 427.83 ± 23.16 g, 396.71 ± 27.86 g, and ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and wogonin on the reversal of multidrug resistance in K562/A02 cell line
... for 4 hours at 4 ° C in ...at 4 ° C in 2% osmium tetroxide for 2 hours, and dehydrated in a graded series of ethanols and embedded in epoxy ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>/DNR magnetic nanoparticles in the treatment of hematologic malignancies
... Ferric chloride, ferrous sulfate, and ammonia water were obtained from Hanguang Chemical Reagent Co, Ltd (Shanghai, China). Albumin was prepared from human plasma obtained from Shanghai RAAS Blood Products Co Ltd ...
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