Bi/sub 4/Ti/sub 3/O/sub 12/ buffer layer
Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... molecular weights. Immunoblots for expression of p38, p-p38, JNK, p-JNK, HO-1, ERK, c-Jun, cleaved caspase 3, Bcl2, Bax, P50, p53, Nrf2, Akt, and GAPDH were detected. All antibodies for Western blot in this study ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... Fe 3 O 4 -PLGA-PEG 2000 -doxorubicin has dose-dependent and time-dependent cytotoxicity against the A549 lung can- cer cell line (IC 50 ...Fe 3 O 4 -PLGA-PEG 3000 -doxorubicin ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Samples of tumor tissue weighing 0.1 g was collected from each mouse and homogenized for detection of P- glycoprotein, Bcl-2, Bax, and caspase-3. Briefly, the tissues were extracted with Triton X-100, and the ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... Fe 3 O 4 nano magnetofluid (0.5, 1.0, 1.5, and 2.0 g/L Fe 3 O 4 ), and a simple magnetic field irradiation group (a negative control group plus magnetic field ...and 4 kW ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... MNPs-Fe 3 O 4 (100:1 M/M) was used to measure the apoptosis ...MNPs-Fe 3 O 4 or the copolymer of MNPs-Fe 3 O 4 and ART for 48 hours, K562 cells were ...
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Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... The phase structure of the nanoparticles was obtained by X-ray diffraction (Cu K α 1.5406 Å radiation), using a Bruker D8 Advance diffractometer (Bruker AXS, Billerica, MA, USA) at room temperature between 20 ° –25 ° , ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... least 4 hours, the formazan crystals were dissolved in 150 µ L dimethyl sulfoxide (Sigma Aldrich) and the reduc- tion of MTT was quantified by absorbance at a wavelength of 570 nm using a microplate reader ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... assay buffer (Sigma-Aldrich) containing protease inhibitors (Sigma- ...at 4°C with the respective primary antibodies in Tris-buffered saline and Tween 20 ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... cells/mL with RPMI-1640. The adjusted cells were placed in a 96-well microtiter plate in 200 µ L aliquots and cultured in the presence of T-lymphocytes mitogen (5 µ g/mL Con- canavalin A [ConA]) (Sigma Chemical Co, St. ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... HAuCl 4 solution containing ...in 3% bovine serum albumin and phosphate-buffered solution at 37 ° C for one hour to block excess active groups and nonspecific binding sites on the ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... Fe 3 O 4 -PLGA-cRGD NPs, it is unclear if Fe 3 O 4 -PLGA-cRGD NPs can be visualized in a thrombus ...Fe 3 O 4 -PLGA-cRGD NPs and their potential to ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... Fe 3 O 4 @SiO 2 -based drug delivery system that combines three properties: magnetic targeting, TfR targeting, and high DOX ...Fe 3 O 4 @ SiO 2 nanoparticle (DMP) was synthesized ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... MNP-Fe 3 O 4 adaptations in the face of elevated sympathetic nervous system ...MNPs-Fe 3 O 4 has no significant influence on the expression profile of KCNQ 1 in rested or in ...
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Characteristics of magnetic labeling on liver tumors with anti-alpha-fetoprotein-mediated Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... For these MFs, the hydrodynamic diameters of MNPs, as well as the MNPs with anti-AFP and anti-CEA coating, are 57.3 ± 15.2 nm, 54.3 ± 10.1 nm, and 54.4.0 ± 10.5 nm, respec- tively (Figure 2A). The measured saturation ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>/DNR magnetic nanoparticles in the treatment of hematologic malignancies
... Fe 3 O 4 -MNPs/DNR are mainly used for chemotherapy and thermotherapy, and may be in contact with blood directly or indirectly for a long time, so evaluation of their hemocompatibility is very ...Fe ...
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Inhibitory effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
... were injected with 2.5 mg/kg HHT or HHT-MNP-Fe 3 O 4 . The treatment was carried out three times without interval in 3 days by the tail vein. Tumor volume was measured at days 7, 14, 21, and ...
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Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents
... Van/Fe 3 O 4 @SiO 2 @Ag microflower with enhanced antibacterial activity is experimentally and theoretically presented in this ...vancomycin layer to bind to the bacterial cell wall and ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... mono- layer on the coverslips was then fixed with methanol-acetone (1:1, v/v), followed by nuclear staining with Hoechst 33258 and examination under fluorescence ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... In order to examine the expression of caspase-3, bax, bcl-2, NF- κ B, and survivin, we next performed Western blot analysis on whole cell protein extracted from cells treated for 48 hours as described previously. ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... Fe 3 O 4 -MNPs was about 20 nm. After modification of the Fe 3 O 4 -MNPs with gold shell, the average diameter of the resulting core–shell Fe 3 O 4 @Au ...
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