Binding activity
DNA-binding activity of papillomavirus proteins.
... Further characterization of the DNA-binding activity of these E2 proteins at 50 mM NaCl, pH 7.0, demonstrated that all [32P]-labeled DNAs, including pBR322, were bound with equal efficie[r] ...
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Fibrinogen and Fibronectin Binding Activity and Immunogenic Nature of Choline Binding Protein M
... A major focus of this study was to determine whether CbpM reacts with the sera obtained from pneumococcal patients and binds to fibri- nogen and fibronectin as plasma proteins. As in- dicated in the results section, CbpM ...
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Regulation of Sp2 DNA-Binding Activity and trans-Activation
... the binding of EYFP-Sp2 to DNA, protein/DNA-binding assays were challenged with an Sp2-specific ...DNA-binding activity can be detected in many human and mouse cell lines, and inclusion of ...
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Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34+ Hematopoietic Progenitor Cells and Humanized NSG Mice
... ligand binding promoted higher levels of FLT3 phosphorylation than that without ligands ...constitutive activity, promotes the formation of a cell type that is capable of productive ...ligand binding ...
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Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants.
... the activity, we isolated the mutant viruses that were not neutralized with the soluble form of MHV receptor proteins, since such mutants were expected to have mutations in amino acids respon- sible for ...
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Hemoglobin binding activity and hemoglobin-binding protein of Prevotella nigrescens
... the fact that intact cell was found to actively bind to hemoglobin may be functionally useful to catch he- moglobin from the bacterial environment. However, the binding activity of the outer membrane was ...
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The calcium binding activity of fish scale protein hydrolysates
... The results of this study showed that enzymatic hy- drolysis was the effective way to recover the calcium- binding peptide form fish scales. The F3 fraction sepa- rated by Sephadex G-15 chromatography possessed ...
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A Secreted Tumor-Suppressor, mac25, with Activin-Binding Activity
... not been found in IGF-BPs. Eighteen cysteine residues, putative sites of S-S bonds, are also found in mac25 (Fig. 1B). The carboxyl termi- nus (about 30 amino acids) of FS is absent from mac25 (4). A carboxyl terminally ...
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SUMO 1 possesses DNA binding activity
... enzymatic activity and the mod- ification of interaction patterns with third partners such as proteins and DNA have been ...SUMO binding motifs (SBMs) to the sumoylated target ...and activity to the ...
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Constitutive and inducible kappa B binding activities in the cytosol of v-Rel-transformed lymphoid cells.
... The biochemical properties of Rel/NF- k B proteins have been the subject of extensive analysis. Most family members reside in the cytoplasm in an inactive, but inducible, form by virtue of interaction with a set of ...
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Rat lung contains a developmentally regulated manganese superoxide dismutase mRNA binding protein
... the binding requires the presence of free sulfhydryl ...protein activity is developmentally regulated; there is less MnSOD RNA-protein binding activity in adult rat lung extract compared to ...
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Selective Suppression of NF-kBp65 in Hepatitis Virus-Infected Pregnant Women Manifesting Severe Liver Damage and High Mortality
... DNA binding activity of NF-kB p50 and NF-kB p65 in pregnant fulminant hepatic failure (FHF) patients and compared them with their nonpregnant ...DNA-binding activity of NF-kB was very high in ...
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The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA.
... Furthermore, since no induction of binding activity was observed on a single-site probe data not shown, we conclude that the activation is not simply an induction of DNA-binding activity[r] ...
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Evaluation of antimicrobial activity of a lectin isolated and purified from Indigofera heterantha
... lectin activity was inhibited by sucrose, D-galactose and ...tinating activity was lost when heated at 100˚C for 30 minutes and was completely lost at ...hemagglutinating activity with in- creasing ...
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Binding of Transmissible Gastroenteritis Coronavirus to Cell Surface Sialoglycoproteins
... acid binding activity is dispensable for virus growth in cell ...the binding of TGEV to cultured cells is mediated only by the interaction with aminopeptidase N or whether the sialic acid ...
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Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity.pdf
... We therefore conclude that the MAD-3 translation product specifically inhibits NF-KB DNA-binding activity and does not inhibit the DNA-binding activity of KBFl , ma[r] ...
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The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study
... overlapping binding pockets (Supplemental ...weaker binding to a phosphorylated, active form, more pronounced for the gatekeeper variant, TKI258 retains its inhibitory activity towards the gatekeeper ...
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New differentially expressed genes and differential DNA methylation underlying refractory epilepsy
... of binding, transport, and enzymatic activity were found, which is consistent with previous studies ...protein binding, receptor binding, channel activity, transporter activity, ...
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Original Article Inhibitory effect of midkine-binding peptide on tumor proliferation and migration
... Single-stranded DNA (ssDNA) was prepared from the identified phage clones as described in the kit guidelines and sequencing was carried out by Invitrogen. The primer used for sequencing was: 5’-CCCTCATGTTAGCGTAA- CG-3’. ...
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RSK2 Binding Models Delineate Key Features for Activity
... As shown in Figure 3, the binding model of 2 illustrates how well the compound is suited for the NTKD ATP site. The optimal packing of 2 in RSK2 may be the basis for its RSK specificity [23]. Compound 2 forms ...
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