Biological Pathways
Context-based resolution of semantic conflicts in biological pathways
... In this study, we introduced a novel systematic analysis for identifying biological pathways with conflict informa- tion. The unexpectedly high rate of conflicts could be explained by two different ways: ...
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Identification of long non-coding RNA competing interactions and biological pathways associated with prognosis in pediatric and adolescent cytogenetically normal acute myeloid leukemia
... identify biological pathways that were indi- cators of AML’s prognosis, significant modules associ- ated with OS and clinical features were selected to carry out functional enrichment ...4 biological ...
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Evaluation of biological pathways involved in chemotherapy response in breast cancer
... This study included 51 ER-negative and 82 ER-positive tumors from patients with newly diagnosed stage I-III breast cancer. Each patient had a fine needle aspiration of the cancer before starting chemotherapy. These ...
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PathwayMatrix: visualizing binary relationships between proteins in biological pathways
... Biological pathways consist of interactions and biochem- ical reactions between sets of proteins and other biomo- lecules resulting in a product or a change in cellular state or activity ...some ...
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The multiscale backbone of the human phenotype network based on biological pathways
... One study by Goh, et al. [1], explored the HDN built on genes shared by different diseases. Another study, which is similar in some ways to ours, by Li et al. [11] traced the SNPs connecting disease traits. In 2009, ...
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Encoding the states of interacting proteins to facilitate biological pathways reconstruction
... Our simple logical model of PPI shows how to take account of this essential information considering the “state” of interacting proteins before and after the inter- action. The lack of these data (that would be saved in ...
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Rett syndrome – biological pathways leading from MECP2 to disorder phenotypes
... of biological knowledge and research results is ne- cessary, and interactive biological pathways help to organize, analyze, and visualize existing ...underlying pathways of the variety of RTT ...
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ReactionFlow: an interactive visualization tool for causality analysis in biological pathways
... Our interviews with domain experts show that our visualization techniques, and especially our ability to represent causality in different ways, have the potential to be useful to the larger community of researchers ...
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Extended LineSets: a visualization technique for the interactive inspection of biological pathways
... of biological pathways can be formalized as a hypergraph, a graph that contains hyperedges which can connect to any number of ...a biological pathway data: biochemical reactions can involve ...
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Plotting the intertwining psychological and biological pathways linking stress and health
... Further, an analysis of a sample of 401 from the Health Women Study showed that a low level of reserve capacity as indexed by several measures of psychosocial resources was linked to a h[r] ...
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Socioeconomic status and health: exploring biological pathways
... proximal pathways – the end-point where proximal, distal and fundamental causes are translated by biological processes into biological aberrations and subsequent ill ...examines biological ...
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DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4
... DrugCIPHER-CS is an efficient drug–target prediction method that was successfully applied to our recent work [16,17]. In the current paper, we investigated the pharma- cological mechanism of DQP using DrugCIPHER-CS to ...
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Prevalence of Microalbuminuria and It's correlation with duration and severity of Hypertension
... 2.5 Factors that cluster with microalbuminuria Microalbuminuria may be related to target organ damage by several biological pathways: Insulin resistance Central obesity Low levels of hig[r] ...
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A prospective study on urinary microalbuminuria as surrogate marker of vascular endothelial dysfunction, in patients of ischemic stroke
... several biological pathways like renal dysfunction, transvascular escape of albumin, endothelial dysfunction and inflammation microalbuminuria as an independent risk factor for ischemic stroke has been ...
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Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex
... the biological process of axon guid- ...on biological pathways involved in autism, both by targeting oxytocin receptor expression and targeting several gene ontology pathways that are relevant ...
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Eimeria maxima induced transcriptional changes in the cecal mucosa of broiler chickens
... top pathways enriched in the upregulated DEGs were ribosome, lysosome, phago- some, cell adhesion molecules, insulin signaling path- way and Herpes simplex infection pathways ...the pathways enriched ...
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Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
... on biological pathways in astrocytes, we studied possible effects of fluoxetine on expression of Cx43 and AQP4 in astrocytic cell lines through cAMP and its newly de- scribed downstream Epac (exchange ...
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SEA: a novel computational and GUI software pipeline for detecting activated biological sub-pathways
... different pathways using differential expression ...a biological pathways that best correspond to their molecular profile data in an easy to use GUI ...
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Transcriptomic profiles of skeletal muscle tissue following an euglycemic-hyperinsulinemic clamp in insulin-resistant obese subjects
... Lists of differentially expressed genes were imported into Ingenuity Pathway Analysis (IPA) system (Ingenuity Ò Systems, www.ingenuity.com). Pathway analyses allowed to determine whether genes found to be differentially ...
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Identification of Significant Genes and Pathways Related to Lung Cancer via Statistical Methods
... and biological pathways that are related to lung cancer by statistical method and pathway enrichment ...significant pathways, such as Metabolism of xenobiotics by cytochrome P450-Homo sapiens (human) ...
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