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Biological therapy

The Danish National Registry for Biological Therapy in Inflammatory Bowel Disease

The Danish National Registry for Biological Therapy in Inflammatory Bowel Disease

... for Biological Therapy in Inflammatory Bowel Disease are to ensure that biological therapy and the clinical management of patients with inflamma- tory bowel disease (IBD) receiving ...

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Short term risk of major adverse cardiovascular events or congestive heart failure in patients with psoriatic arthritis or psoriasis initiating a biological therapy: a meta–analysis of randomised controlled trials

Short term risk of major adverse cardiovascular events or congestive heart failure in patients with psoriatic arthritis or psoriasis initiating a biological therapy: a meta–analysis of randomised controlled trials

... psoriasis, based on the assumption that in both of these chronic inflammatory diseases, there is an increase in the risk of MACEs and they both require several biolog- ical therapies. This resulted in a higher number of ...

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Patients’ conceptions of their own influence on good treatment response to biological therapy in chronic inflammatory arthritis

Patients’ conceptions of their own influence on good treatment response to biological therapy in chronic inflammatory arthritis

... undergoing biological therapy conceived their own influence on good treatment response in terms of adher- ence, physical activity, mental attitude, social support, and ...

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Applying science in practice: the optimization of biological therapy in rheumatoid arthritis

Applying science in practice: the optimization of biological therapy in rheumatoid arthritis

... measured by response criteria, but the remaining infl am- matory activity (status) seems decisive: ‘It is good to feel better but it is better to feel good’ [1]. Aletaha and colleagues [2] have demonstrated, in a pooled ...

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Biological therapy of traditional therapy-resistant adult-onset Still’s disease: an evidence-based review

Biological therapy of traditional therapy-resistant adult-onset Still’s disease: an evidence-based review

... However, the data about the availability of abatacept is so limited that its tolerance cannot be evaluated. Further studies are required to assess the better use of both biologics in AOSD patients. If possible, ...

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A nurse led rheumatology clinic versus rheumatologist led clinic in monitoring of patients with chronic inflammatory arthritis undergoing biological therapy: a cost comparison study in a randomised controlled trial

A nurse led rheumatology clinic versus rheumatologist led clinic in monitoring of patients with chronic inflammatory arthritis undergoing biological therapy: a cost comparison study in a randomised controlled trial

... An NLC, based on PCC was designed to monitor pa- tients’ biological therapy. After randomisation to the NLC, patients received information about contact details to their rheumatology nurse, and that they ...

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Biological Therapy and Risk of Malignancies: A Literature Review

Biological Therapy and Risk of Malignancies: A Literature Review

... of etanercept the prevailing effect would appear favor- able. One hypothesis to explain the lower incidence of lymphoma observed with etanercept (a soluble fusion protein) compared to monoclonal antibodies, is probably ...

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A Single Center Experience in Biological Therapy for the Treatment of Rheumatoid Arthritis in Saudi Arabia

A Single Center Experience in Biological Therapy for the Treatment of Rheumatoid Arthritis in Saudi Arabia

... of biological therapy was ADA and the second choice biological therapy after the fail- ure of the first was RTX, which is consistent with the ACR/EULAR recommendations [14] [15] ...of ...

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Where is biological therapy going?

Where is biological therapy going?

... progression, biological therapy has not yet met the expectations of permanently silencing chronic (auto)immune ...exciting biological tools will enter the clinic and be tested for their efficacy in ...

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How do patients with inflammatory bowel disease want their biological therapy administered?

How do patients with inflammatory bowel disease want their biological therapy administered?

... It is unclear why patients with RA and IBD differ in their preferences for biological therapy. Some possible explanations may include the following: (1) RA patients may be more immobile and therefore have ...

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Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease

Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease

... anti-TNFa therapy is strongly indicated as front line therapy, such as the use of rescue infliximab in the setting of acute severe ulcerative colitis, when patients have failed standard treatment with ...

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Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines

Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines

... disc therapy: anti-catabolics, mitogens, mor- phogens, and intracellular ...the biological mechanisms of each ...proven biological therapy for degeneration of human ...

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Review of the treatment of psoriatic arthritis with biological agents: choice of drug for initial therapy and switch therapy for non-responders

Review of the treatment of psoriatic arthritis with biological agents: choice of drug for initial therapy and switch therapy for non-responders

... with biological therapy. Since no specific biological agent has been demonstrated to be more effective than others, the drug choice should be made according to the available safety data, the presence ...

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Case Report Gastric metastasis from breast infiltrating ductal carcinoma: a case report

Case Report Gastric metastasis from breast infiltrating ductal carcinoma: a case report

... as biological therapy for patients with Her2- positive breast ...Hormonal therapy is only given to the patient whose cancer posi- tively expresses hormone receptors (estrogen or progesterone ...

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Perceptions of patients with rheumatic diseases on the impact on daily life and satisfaction with their medications: RHEU-LIFE, a survey to patients treated with subcutaneous biological products

Perceptions of patients with rheumatic diseases on the impact on daily life and satisfaction with their medications: RHEU-LIFE, a survey to patients treated with subcutaneous biological products

... antirheumatic therapy was high ...SC biological therapy perceive a high disease impact on different aspects of daily life, despite being highly satisfied with their treatment; the perception is that ...

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... festation of ocular involvement was keratoconjunctivitis sicca. Posterior scleritis or scleromalacia of cornea was not present in patients with I or II stage of disease. The new bio-tech therapies provide significant ...

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Low cost biological lung volume reduction therapy for advanced emphysema

Low cost biological lung volume reduction therapy for advanced emphysema

... advanced upper lobe emphysema, comparing high dose treat- ment of 20 mL/subsegment (in 22 patients) and low dose treat- ment of 10 mL/subsegment (in 28 patients). They showed that radiologic response (in the form of ...

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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives

Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives

... The biological function of DOT1L (as well as DOT1) is to methylate H3K79 as part of a transcription complex, which can initiate or maintain an active tran- scription ...

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Production, quality control and biological evaluation of 153Sm-TTHMP as a possible bone palliation agent

Production, quality control and biological evaluation of 153Sm-TTHMP as a possible bone palliation agent

... 153 Sm-TTHMP can be a potential candidate for bone pain palliation therapy in skeletal metastases, although further biological studies in other mammals is still needed[r] ...

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Biological Modulation of Parp Inhibition in Triple Negative Breast Cancer, a Combinational Approach Implementing Multitargeted Epigenetic Therapy (Mtet) with Parp Inhibition, in Advanced Breast Cancer: A Case Study

Biological Modulation of Parp Inhibition in Triple Negative Breast Cancer, a Combinational Approach Implementing Multitargeted Epigenetic Therapy (Mtet) with Parp Inhibition, in Advanced Breast Cancer: A Case Study

... Patient accomplished unexpected response to the combinational therapy of PARP inhibitors and epigenetic protocol, with improved progression free sur- vival and quality of life. She was under our care for three ...

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