bone marrow-derived dendritic cell
Original Article Bortezomib inhibits bone marrow-derived dendritic cells
... Bortezomib has been shown to inhibit NF-κB activity in multiple myeloma cells by blocking IκB degradation [18]. Additionally, Yoshimura et al. study found that NF-κB was an effective tar- get for blocking DC antigen ...
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Comparison of immature and mature bone marrow derived dendritic cells by atomic force microscopy
... resolutions, cell height profile and histogram, topography, and roughness on the surface of the cells (Figure ...smooth cell surface and approximately ...the cell membrane in addition to becoming ...
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Original Article High-dose hepatitis B E antigen drives mouse bone marrow-derived dendritic cells to differentiate into regulatory dendritic cells in vitro
... T cell response that probably reflects the efficient capacity of DCs to prime and activate antiviral T cells [22, ...T cell to shift toward a Th1 cells, a T-cell subtype required for elimination of ...
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Phenotypic and functional abnormalities of bone marrow derived dendritic cells in systemic lupus erythematosus
... processing antigens (Ags). After migration to the lym- phoid organs, where they become mature, their ability to capture and process Ags decreases, whereas that for Ag presentation increases [5]. After maturation, DCs are ...
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The effect of the cholinergic anti inflammatory pathway on collagen induced arthritis involves the modulation of dendritic cell differentiation
... are derived from hematopoietic stem cells or per- ipheral blood mononuclear cells [47, ...mouse bone marrow pro- genitor cells through stimulation with GM-CSF and IL-4 in vitro [53], and LPS can ...
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Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus
... apoptotic cell- pulsed bone marrow-derived DCs (AC-BMDCs) could induce the proliferation of self reactive T-cells resulting in tolerance break down and initiation of autoimmune responses in ...
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In vitro transfection of bone marrow-derived dendritic cells with TATp-liposomes
... eukaryotic cell expression of the EGFP was obtained from Elim Biopharmaceuticals Inc (Hayward, CA, ...eukaryotic cell expression systems with cytomega- lovirus promoter pCI-neo (pCIneo), and BamHI and EcoRI ...
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Modulation of Gene Expression Related to Toll-Like Receptor Signaling in Dendritic Cells by Poly(γ-Glutamic Acid) Nanoparticles
... murine bone marrow-derived dendritic cells (DCs) treated with ␥ -PGA NPs was examined by oligonucleotide microarray analysis and compared with that in cells treated with other ...
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A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis
... 17]. Bone marrow-derived macrophages (BMMØs) were derived from bone marrow using L929-conditioned media and ac- tivated for 18 h with recombinant IFNγ (rIFNγ) (100 U/ ml, Pepro ...
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New application of anti-TLR monoclonal antibodies: detection, inhibition and protection
... BM-cDC: bone marrow-derived conventional dendritic cell; BM-MC: bone marrow-derived macrophage; BM-pDC: bone marrow-derived plasmacytoid ...
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IL-15 Generates IFN-γ-producing Cells Reciprocally Expressing Lymphoid-Myeloid Markers during Dendritic Cell Differentiation
... immune cell differentiation and the use of IL-15 in the phenotypic characterization of incompletely defined IFN-γ-producing innate cells such as IKDCs or pre-mNK cells, NK cells, NKDCs and ILC1s, in the present ...
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Exosomes derived from statin-modified bone marrow dendritic cells increase thymus-derived natural regulatory T cells in experimental autoimmune myasthenia gravis
... II and CD28-CD80/CD86 interaction, which leads to the generation of thymic Treg cell precursors (pre-Treg cells). However, there were no differences among the three groups in the expression of MHC II as well as ...
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Modified Fe3O4 Magnetic Nanoparticle Delivery of CpG Inhibits Tumor Growth and Spontaneous Pulmonary Metastases to Enhance Immunotherapy
... enhanced cell uptake of CpG in bone marrow-derived dendritic cells (BMDCs) in vitro and through intratumoral injection, showed significant antitumor ability by stimulating better ...
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Multi-omics studies demonstrate Toxoplasma gondii-induced metabolic reprogramming of murine dendritic cells
... FIGURE 8 | normalized to unstimulated controls. Red indicates an increase in transcript expression, green indicates a decrease in transcript expression and gray shows no change from control cells. For Clarity, relevant ...
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Bone marrow mononuclear cells and acute myocardial infarction
... stem cell therapy in heart ...stem/progenitor cell is the best candidate for cardiac regeneration. Th e bone marrow is an attractive source because it is easily accessible and contains a ...
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Comparison of Platelet-Rich Plasma (PRP), Bone Marrow-Derived Mesenchymal Stem Cells and their Combination on the Healing of Achilles Tendon in Rabbits
... including bone marrow-derived mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) which has revealed remarkable results in modulation of Achilles tendon ...
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Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity
... According to ClinicalTrail.gov to date, there are 452 studies registered for “mesenchymal stem cells”, 32 stud- ies registered for “induced pluripotent stem cells”, and 27 studies registered for both “mesenchymal stem ...
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Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
... Recent studies indicated that different types of MSC therapy or combined therapies with some unique bio- technology factors can stimulate cutaneous wound healing [28–31]. Current studies have report that a new ...
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Glomerulosclerosis is transmitted by bone marrow–derived mesangial cell progenitors
... DNA analysis. DNA was extracted from the spleens, glomeruli, and isolated cells (12). Clonal populations of glomerular mesangial cells, glomerular endothelial cells, and aortic smooth muscle cells were examined. One mil- ...
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Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking
... RNA expression profiling. RNA was purified from sorted dendritic cells and endothelial cells using the Qiagen RNeasy Micro Kit (74004, Qiagen Technologies). For RNA microarray, libraries were generated using the ...
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