Bone marrow mesenchymal stromal cells
Safety and tolerability of autologous bone marrow mesenchymal stromal cells in ADPKD patients
... BM: Bone marrow; BMA: Bone marrow aspiration; BMMSCs: Bone marrow mesenchymal stromal cells; BP: Blood pressure; BUN: Blood urea nitrogen; CKD: Chronic ...
11
Supernatant of Bone Marrow Mesenchymal Stromal Cells Induces Peripheral Blood Mononuclear Cells Possessing Mesenchymal Features
... some cells from peripheral blood fibroblast-like mononuclear cells have the capacity to differentiate into mesenchymal ...these cells in the circulation challenges the cell isolation and ...
12
Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells
... Growth factors such as VEGF and HGF secreted by MSCs are reported to reduce hepatocyte apoptosis and increase liver regeneration [31]. In the current study, BM-MSCs showed higher levels of VEGF secretion whereas WJ-MSCs ...
12
Heterologous mesenchymal stem cells successfully treat femoral pseudarthrosis in rats
... Bone marrow cells suspension are considered the best choice because, compared with cultures of bone marrow mesenchymal stromal cells, that procedure is more cost ...
10
Application potential of stem/progenitor cell-derived extracellular vesicles in renal diseases
... target cells through transferring protein molecules as well as regulatory effects on the phenotype of target cells through fusion with the target cells membrane and/or through direct endocytosis by ...
9
Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia
... abrogates stromal-induced chemoresistance in lymphoid ...leukemia cells and bone marrow stromal cells remain ...AML cells in co-culture with bone marrow ...
15
Human umbilical cord mesenchymal stromal cells-derived extracellular vesicles exert potent bone protective effects by CLEC11A-mediated regulation of bone metabolism
... During bone remodeling, old or damaged bone is digested by osteoclasts (sole bone-resorbing cells) at a specific site where growth factors are released from the bone matrix to induce ...
16
Bone marrow-derived mesenchymal stromal cells differ in their attachment to fibronectin-derived peptides from term placenta-derived mesenchymal stromal cells
... the cells were saturated with a function blocking mAb against the integrin β1 chain and then attachment to the MSCs binding proteins and peptides was explored ...the cells with a mAb to integ- rin β1 chain ...
14
Culture and Growth Characterization of Human Mesenchymal Stem Cells from Dental Pulp
... of mesenchymal stem cells (MSCs, a term first coined by Arnold Caplan in 1991, can be traced to experiments demonstrating that transplantation of bone marrow (BM) to heterotopic anatomical ...
90
Translation of remote control regenerative technologies for bone repair
... Controlled Differentiation of Human Bone Marrow Stromal Cells Using Magnetic Nanoparticle Technology.. Concise Review: The Surface Markers and Identity of Human Mesenchymal Stem Cells.[r] ...
42
Mesenchymal stromal cells induce a permissive state in the bone marrow that enhances G-CSF-induced hematopoietic stem cell mobilization in mice
... in bone-lining cells after MSC (M) or EV administration for 3 days to recipients that were simultaneously mobilized with G-CSF (G) or PBS (P) as a ...BM cells, granulocytes (Gran), monocytes (Mon), B ...
14
Perinatal sources of mesenchymal stem cells: Wharton’s jelly, amnion and chorion
... stem cells have aroused much greater ...the bone marrow stem cell, hematopoietic and non-hematopoietic, that is able to specialize into blood cells and other mesenchymal ...stem ...
22
Obesity Negatively Affects the Biological Functions of Mesenchymal Stromal Cells Derived from Bone Marrow, Subcutaneous and Visceral Fat of Young Mice
... MSCs are an heterogenous population containing both stem cells and lineage committed progenitors for production of osteocytes, chondrocytes and adipocytes. Hence, in absence of external differentiation cues, in ...
18
Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process
... the bone marrow and affect the resident stem ...stem cells (HSC), while only a few have addressed the effect of IR on the other cell types present in bone marrow, such as ...
12
Allogeneic Guinea pig mesenchymal stem cells ameliorate neurological changes in experimental colitis
... decade, mesenchymal stem cells (MSCs), also known as multipotent stromal cells, have emerged as a clinically viable therapy for many diseases, includ- ing IBD ...and bone marrow; ...
21
Human adult stem cells derived from adipose tissue and bone marrow attenuate enteric neuropathy in the guinea-pig model of acute colitis
... stem cells (MSCs) otherwise known as multipotent stromal cells have been proposed as a potential treatment option for chronic inflammation and neurological damage ...These cells are identified ...
21
Cysteamine treatment restores the in vitro ability to differentiate along the osteoblastic lineage of mesenchymal stromal cells isolated from bone marrow of a cystinotic patient
... Characterization of ex-vivo expanded Cys- and HD-MSCs MSC samples were phenotypically characterized by flow cytometry at P2-P3, using fluorescein isothiocyanate (FITC)- or phycoerythrin (PE)-conjugated monoclonal ...
7
Study on chemotaxis and chemokinesis of bone marrow-derived mesenchymal stem cells in hydrogel-based 3D microfluidic devices
... instance, stromal cell-derived factor-1 α (SDF-1α) mediates cell migration by binding with CXC chemokine receptor-4 (CXCR4) at the site of injury ...that cells cultured using traditional 2D tissue culture ...
8
Efficacy and safety of adult human bone marrow derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint
... million cells) showed improved outcomes in the pain measurement scores, whereas those in the higher dose groups did ...million cells, improvement in pain, disability, quality of life, and cartilage quality ...
18
Are mesenchymal stromal cells immune cells?
... the bone marrow, MSCs have a supportive function for the haematopoietic system and provide a niche for haematopoietic progenitor cells to ...the bone marrow and in other tissues, such ...
7