Bone Marrow Transplantation
Stages in Pediatric Bone Marrow Transplantation
... Stages in Pediatric Bone Marrow Transplantation.. Betty Pfefferbaum, M.D., M. Muriel Lindamood, M.S.W., and.[r] ...
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Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure
... ure, bone marrow failure and increased risk of leukemia ...cell transplantation (HSCT), preferably from matched sibling donors [9-13], whereas HSCT has only rarely been applied in patients with ...
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Immunologic and hematopoietic effects of CD40 stimulation after syngeneic bone marrow transplantation in mice
... receiving the srmCD40L. The treated recipients also dem- onstrated improved B-cell function with increases in total serum immunoglobulin and increased splenic mitogen re- sponsiveness to LPS being noted. Additionally, ...
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Outcome of Pediatric Cataract Surgery in Patients Who Have Undergone Bone Marrow Transplantation
... Bone marrow transplantation (BMT) with pre-treatment conditioning is an es- tablished treatment for childhood leukemia, myelodysplastic syndrome and oth- er hereditary and metabolic hematologic ...
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Cerebral Blood Flow and Marrow Diffusion Alterations in Children with Sickle Cell Anemia after Bone Marrow Transplantation and Transfusion
... Whole-brain mean quantitative cere- bral blood flow significantly decreased fol- lowing BMT, from 77.39 ⫾ 13.78 to 60.39 ⫾ 13.62 mL/100 g tissue/min (first scan; P ⫽ .00004), and did not signifi- cantly change thereafter ...
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MR of cerebral aspergillosis in patients who have had bone marrow transplantation
... PURPOSE: To assess the CT and MR appearance of cerebral aspergillosis in patients who have undergone bone marrow transplantation. METHODS: The imaging and clinical data of five patients with cerebral ...
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Treatment of severe hypercholesterolemia in apolipoprotein E deficient mice by bone marrow transplantation
... Moreover, the extent of atherosclerosis in the E0-treated-HF mice after 14-16 wk was greatly reduced. Wild-type apo E mRNA was detected in the liver, spleen, and brain of the E0- treated mice indicating that apo E gene ...
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Psychological Issues in Bone Marrow Transplantation
... We studied the psychological and emotional problems experienced by seven children and their families who underwent bone marrow transplantation at the Univer- sity of Colorado Medical Cen[r] ...
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Percutaneous autologous bone marrow transplantation for the treatment of delayed union of limb bone in children
... autologous bone marrow transplantation (PABMT) is a minimally invasive therapeutic strategy for the treatment of delayed bone union in adults, which has been confirmed by many ...limb ...
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Bone Marrow Transplantation for Children With Acute Leukemia and Down Syndrome
... had been selected for bone marrow transplantation based on the following eligibility criteria: (1) diag- nosis of acute nonlymphocytic leukemia in first or.. greater remission or acute l[r] ...
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Sequential Liver and Bone Marrow Transplantation for Treatment of Erythropoietic Protoporphyria
... option. The authors performed retrovirus-mediated gene transfer of the human FECH complementary DNA into hematopoietic stem cells (HSCs) from male EPP mice and were able to select successfully transduced cells on the ...
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Novel conditioning regimens for bone marrow transplantation
... Abstract: Bone marrow transplantation (BMT) has evolved into an effective strategy for the treatment of hematological and oncological disorders. Radiotherapy and chemotherapy are used as conditioning ...
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Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector
... The ex vivo transduction procedure used here resulted in a relatively low level of gene transfer in bone marrow cells. A recent report indicates that retrovirus produced in NIH3T3-derived packaging cells ...
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Current Indications of Bone Marrow Transplantation (BMT) in Pediatric Malignant Conditions a Review
... Hematopoietic stem cell transplantation (HSCT) has been practiced for more than 30 years. Hematological malignan- cies are the main indications for this treatment. However, its indications in adults are different ...
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Correction or Transfer of Immunodeficiency Due to TNF-LTα Deletion by Bone Marrow Transplantation
... The lymphocyte count was normalized in TNF-LTa-deficient mice reconstituted with wild- type bone marrow cells, although no lymph node structures were induced. Conversely, the lymphocyte [r] ...
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Bone Marrow Transplantation for Non-Malignant Disease
... International Bone Marrow Transplant Reg- istry (IBMTR); 75 received histocompatible sibling bone marrow, 48 received transplants from relatives other than histocompatible siblings, and 67 ...
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Investigations on Bone Marrow Transplantation in Irradiated Animals Final Report EUR 4663
... During 1966 a major advance in the control of secondary disease was achieved by the introduction of anti-lymphocyte serum to treat the bone marrow recipients after the transplantation.. [r] ...
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Bone marrow transplantation generates T cell–dependent control of myeloma in mice
... ductive and immunosuppressive agents, a scenario that is replicat- ed in our murine model, in which BM grafts were harvested from immunogenically identical but untreated donors. Additionally, the presence of preexisting ...
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Cxcr4 haploinsufficient bone marrow transplantation corrects leukopenia in an unconditioned WHIM syndrome model
... For gene therapy of gain-of-function autosomal dominant diseases, either correcting or deleting the disease allele is potentially curative. To test whether there may be an advantage of one approach over the other for ...
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Bone marrow transplantation (BMT), nowadays
... Very small embryonic-like stem cells (VSELs) are possibly lost during cord blood banking and bone marrow (BM) processing for autologus stem cell therapy mainly because of their small size. The present study ...
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