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Bone sarcoma

Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma

Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma

... by sarcoma cells. However, sarcoma cells like other cancer cells frequently show a differential size compared to normal cells and a lower ...in bone sarcoma ...

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Workshop report on the 2nd Joint ENCCA/EuroSARC European bone sarcoma network meeting: integration of clinical trials with tumour biology

Workshop report on the 2nd Joint ENCCA/EuroSARC European bone sarcoma network meeting: integration of clinical trials with tumour biology

... to bone sarcoma research in adolescents and young adults were presented by Dan ...of bone sarcomas in TYA than in chil- dren or adults, including response to therapy and survival, which is difficult ...

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Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

... of bone sarcoma cells and could represent an important step in the pathogenesis of bone ...of bone sarcoma cells. Indeed, stimulation of bone sarcoma cells with Wnt3a led ...

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Early decrements in bone density after completion of neoadjuvant chemotherapy in pediatric bone sarcoma patients

Early decrements in bone density after completion of neoadjuvant chemotherapy in pediatric bone sarcoma patients

... Ewing’s sarcoma patients six years after ...tric bone sarcoma survivors; it may develop in the long run and persist for several ...since sarcoma patients are at increased risk for developing ...

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An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG).

An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG).

... 21 Healy JC, Reznek RH, Clark SK et al. MR appearances of desmoid tumors in familial adenomatous polyposis. AJR Am J Roentgenol 1997; 169: 465-472. 22 Castellazzi G, Vanel D, Le Cesne A et al. Can the MRI signal of ...

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miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors

miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors

... epigenetic regulation of TAp73β through miRNAs has already been described and interestingly, even if in silico analysis predicts that the miRs -125b, -486-3p and -34a could potentially target TAp73 [37], only the ...

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Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials

Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials

... Ewing sarcoma patients have been reported, [23] as have responses to Apo2L/TRAIL therapy in chondrosarcoma ...Ewing sarcoma patients were seen, the availability of a promising agent increased referral of ...

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ALDH Activity Correlates with Metastatic Potential in Primary Sarcomas of Bone

ALDH Activity Correlates with Metastatic Potential in Primary Sarcomas of Bone

... tured bone sarcoma cells. Human bone sarcoma cells were trypsinized, washed with DPBS, and counted using a hemocytometer. Cells were then resuspended in Aldefluor buffer at a concentration of ...

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The challenge of finding new therapeutic avenues in soft tissue sarcomas

The challenge of finding new therapeutic avenues in soft tissue sarcomas

... and Bone Sarcoma Group (STBSG) 62012 phase III study including 455 patients treated either with single-agent doxorubicin or with a combination regimen of doxorubicin plus high-dose ifosfamide the primary ...

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Neoadjuvant chemotherapy for primary sarcoma of the breast: a case report

Neoadjuvant chemotherapy for primary sarcoma of the breast: a case report

... and Bone Sarcoma Group (EORTC-STBSG) proposed that therapeutic re- sponse should be evaluated by the change on pathological findings of stainable tumor cells and necrotic area for the entire tumor following ...

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Features of Bone Sarcomas at MAHAK Children Hospital, Tehran, Iran during 2007-2009

Features of Bone Sarcomas at MAHAK Children Hospital, Tehran, Iran during 2007-2009

... According to clinical manifestations and primary tumor site, we classified patients. The treatment of childhood bone sarcoma in MAHAK children hospi- tal is performed according to German protocol. Initially ...

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Long lasting clinical response to chemotherapy for advanced uterine leiomyosarcoma: a case report

Long lasting clinical response to chemotherapy for advanced uterine leiomyosarcoma: a case report

... and Bone Sarcoma Group of the European Organization for Research and Treatment of Cancer [10] evaluated the use of 750mg/m 2 of oral te- mozolomide divided over five days every four weeks in 31 patients ...

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Negative and positive consequences of cancer treatment experienced by long term osteosarcoma survivors : a qualitative study

Negative and positive consequences of cancer treatment experienced by long term osteosarcoma survivors : a qualitative study

... of bone cancer survivors’ experiences after extensive surgery in the hip/pelvis region demonstrated how treatment and long-term consequences affect bone sarcoma survivors ...

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A rare case of low grade myofibroblastic sarcoma of the femur in a 38 year old woman: a case report

A rare case of low grade myofibroblastic sarcoma of the femur in a 38 year old woman: a case report

... have been shown to play an important role in wound healing [4]. In addition, myofibroblasts have been recog- nized in pseudosarcomatous proliferations, hypertrophic scars, and superficial and deep fibromatoses [3]. Over ...

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Original Research Article Study of prevalence of primary bone tumors at a tertiary care centre in Central India

Original Research Article Study of prevalence of primary bone tumors at a tertiary care centre in Central India

... primary bone tumors confirmed by histopathology have been included in the ...of bone tumors like pain, swelling, weakness, range of motion of the involved joint, any sensory or motor deficit, rapid growth, ...

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New drugs and combinations for the treatment of soft-tissue sarcoma: a review

New drugs and combinations for the treatment of soft-tissue sarcoma: a review

... Trabectedin was approved by the European Union in 2007 for the treatment of patients with STS who progress on or are not candidates for anthracycline- or ifosfamide-based therapy. In the US, a randomized phase III ...

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Utility of Multi-Parametric Quantitative Magnetic Resonance Imaging for Characterization and Radiotherapy Response Assessment in Soft-Tissue Sarcomas and Correlation With Histopathology.

Utility of Multi-Parametric Quantitative Magnetic Resonance Imaging for Characterization and Radiotherapy Response Assessment in Soft-Tissue Sarcomas and Correlation With Histopathology.

... retroperitoneal sarcoma were included in this prospective single-center ...retroperitoneal sarcoma with planned surgical resection, with or without pre-operative ...retroperitoneal sarcoma; one had a ...

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Non-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review

Non-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review

... biopsy of the tumor mass and its histopathologic and immu- nohistochemical analysis. Hematologic malignancies such as lymphoma, blastic plasmacytoid dendritic cell neoplasm, and non-hematopoietic tumors should be ...

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Delayed Presentation of Bone and Soft Tissue Sarcoma of the Extremity in Makurdi: Do Traditional Bone Setters Play a Role?

Delayed Presentation of Bone and Soft Tissue Sarcoma of the Extremity in Makurdi: Do Traditional Bone Setters Play a Role?

... of traditional bone setters in cancer treatment in our region has constituted a new and worrisome source of delay. Patients who went for traditional treatment before presentation to our unit were observed to have ...

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