bonferroni correction
An Efficient Association Test for High Dimensional Data, with Application in Genetic Studies
... burden. Bonferroni correction α/m, where m is the number of hypothesis tests conducted, is the most basic method for controlling the type I error α but it is well known to be con- servative when the ...
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On the Sample Size Requirement in Genetic Association Tests When the Proportion of False Positives Is Controlled
... the Bonferroni approach can outperform the PFP ap- proach in the aforementioned ...to Bonferroni correction by setting corresponding (different) levels of PFP and ...the Bonferroni ...
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Integration of Enhancer-Promoter Interactions with GWAS Summary Results Identifies Novel Schizophrenia-Associated Genes and Pathways
... the Bonferroni correction, for the larger SCZ data set with 36,989 cases and 113,075 controls, our method applied to the gene body and enhancer regions identified 27 novel genes and 11 novel KEGG pathways to ...
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Ultra-high resolution optical coherence tomography for monitoring tear meniscus volume in dry eye after topical cyclosporine treatment
... Data analysis was conducted using Statistica software (v. 10; StatSoft, Tulsa, OK). Two-way repeated-measures analysis of variance was used for overall effects and post-hoc paired t-tests, with Bonferroni ...
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An Eigenvalue test for spatial principal component analysis
... an sPCA. While the global test failed to provide statistical significance, the spca_randtest did obtain significant results and pointed to the three first most positive compo- nents to be also significant after ...
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Mendelian inheritance, genetic linkage, and genotypic disequilibrium for nine microsatellite loci in Cariniana estrellensis (Raddi) Kuntze (Lecythidaceae).
... After Bonferroni correction, we found no deviation from 1:1 Mendelian segregation for the nine loci analyzed for ...after Bonferroni correction, we detected no deviation from 1:1:1:1 Mendelian ...
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A comparison of some methods for detection of safety signals in randomised controlled trials
... the Bonferroni correction (BONF) ([5]); control of the False Discovery Rate (FDR) by the Benjamini-Hochberg procedure ([6]); control of the False Discovery Rate by a number of grouping procedures: the ...
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Cortical Morphometric Subclassification of Frontotemporal Lobar Degeneration
... SD versus Controls. The t tests with Bonferroni correction revealed that all temporal areas were significantly atrophic in patients with SD (Fig 2A). Left and right TEMPs displayed ⬎ 50% volume loss ...
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Influence of aging on medial olivocochlear system function
... Comparisons of the amplitude of otoacoustic emission with- out or with contralateral stimulation and of the MOC effect in different subgroups were made. Factorial analysis of variance (ANOVA) with two categorical ...
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Weighted multiple testing procedures for genomic studies
... In the context of high-dimensional data analysis, using a procedure that guards against any single false positive occurring can lead to additional missed findings i.e. increased Type II error rates. Benjamini and ...
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Investigation of the Appropriate Partial Level Density Formula for Pre Equilibrium Nuclear Exciton Model
... This correction comes from pairing property between couples of particles. Therefore, this pairing required en- ergy, which is taken from the excitation energy and hence the excitation energy will decrease [12-14]. ...
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The correlations between the anchor density and the curve correction of adolescent idiopathic scoliosis surgery
... Pedicle screws instrumentation and posterior fusion have become the treatment of choice in AIS surgery [1–3]. Al- though, with the advancement of pedicle screw insertion techniques and electroneurophysiological ...
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Schur m power convexity of generalized geometric Bonferroni mean involving three parameters
... We discuss the Schur m-power convexity of the generalized geometric Bonferroni mean with three parameters. The given results are a generalization of the previous results ob- tained in [48, 49]. Our approach may ...
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Classification with Measurement Error in Covariates Or Response, with Application to Prostate Cancer Imaging Study
... of correction methods is to directly correct the naive estimators which are obtained by treating the X ∗ as X and carrying out the usual estimating ...estimator correction strategy, discussed by Stefanski ...
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The multiple impulse method of tooth mobility assessment
... Statistical analysis of the data was performed using S AS computer software. The table shows differences between the means which were evaluated using Bonferroni (Dunn) T tests for the variable of Periotest value ...
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Microsatellite variation in Australian and Indonesian pearl oyster Pinctada maxima populations
... Data on the sequence of a number of alleles has also been reported, and showed that size anomalies exhib- ited by 3 loci (Pmx 16_23, Pmx + 020 and Pmx 18_21) are explained by ≥ 1 insertion/deletion event(s) (indels) ...
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Schur convexity of the generalized geometric Bonferroni mean and the relevant inequalities
... This paper is a follow-up study of our recent work [24], we generalize the geometric Bon- ferroni mean by introducing three non-negative parameters p, q, r, under the condition of p + q + r = 0, we prove that the ...
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Integrative analysis of genetic data sets reveals a shared innate immune component in autism spectrum disorder and its co morbidities
... To adjust the combined p values, we considered differ- ent FDR corrections [i.e., Bonferroni, Benjamini–Yekutieli (BY), and Benjamini–Hochberg (BH)]. We also considered the ‘no correction’ case for ...
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Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development
... The genotypes from three independent lung cancer GWAS including a total of 24,037 lung cancer patients and 20,401 health controls with European ancestry were collected for the study. Demographic and clinical ...
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The impact of total sleep deprivation upon cognitive functioning in firefighters
... for Bonferroni post hoc correction, we confirmed that the sample group obtained better results in terms of the greater number of cor- rect responses in the CRT test as well as a shorter reaction time for ...
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