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Borna Disease Virus

The Nucleolus Is the Site of Borna Disease Virus RNA Transcription and Replication

The Nucleolus Is the Site of Borna Disease Virus RNA Transcription and Replication

... Borna disease virus (BDV) is a neurotropic nonsegmented negative-strand RNA virus with limited homology to rhabdoviruses and paramyxoviruses. A distinguishing feature of BDV is that it ...

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Splicing-Dependent Subcellular Targeting of Borna Disease Virus Nucleoprotein Isoforms

Splicing-Dependent Subcellular Targeting of Borna Disease Virus Nucleoprotein Isoforms

... Borna disease virus 1 (BoDV-1) is a nonsegmented, negative-strand RNA virus that replicates and transcribes in the nucleus. The BoDV genome harbors at least six open reading frames (ORFs), as ...

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Constitutive Activation of the Transcription Factor NF-κB Results in Impaired Borna Disease Virus Replication

Constitutive Activation of the Transcription Factor NF-κB Results in Impaired Borna Disease Virus Replication

... RNA virus infection and is a key player in the induction and regulation of the innate immune ...response. Borna disease virus (BDV) is a neu- rotropic negative-strand RNA virus, which ...

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Borna Disease Virus Infection Impairs Synaptic Plasticity

Borna Disease Virus Infection Impairs Synaptic Plasticity

... Borna disease virus (BDV) is an enveloped virus with a nonsegmented, negative-strand RNA genome belonging to the Bornaviridae family within the Mononegavirales order (6, ...neurotropic ...

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Synaptic Pathology in Borna Disease Virus Persistent Infection

Synaptic Pathology in Borna Disease Virus Persistent Infection

... Borna disease virus (BDV) infection of newborn rats leads to a persistent infection of the brain, which is associated with behavioral and neuroanatonomical ...

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Isolation of Borna Disease Virus from Human Brain Tissue

Isolation of Borna Disease Virus from Human Brain Tissue

... that Borna disease virus (BDV) can infect humans and is possibly associated with certain neuropsychiatric ...BDV. Virus isolation was also possible by transfection of Vero cells with ...

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Characterization of Borna disease virus p56 protein, a surface glycoprotein involved in virus entry.

Characterization of Borna disease virus p56 protein, a surface glycoprotein involved in virus entry.

... Borna disease virus (BDV) is a nonsegmented negative-stranded (NNS) RNA virus, prototype of a new taxon in the Mononegavirales ...neurologic disease manifested by behavioral ...

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Prevention of Virus Persistence and Protection against Immunopathology after Borna Disease Virus Infection of the Brain by a Novel Orf Virus Recombinant

Prevention of Virus Persistence and Protection against Immunopathology after Borna Disease Virus Infection of the Brain by a Novel Orf Virus Recombinant

... Orf virus represents a promising candidate for novel vector vaccines due to its immune modulating properties even in nonpermissive hosts such as mouse or ...Orf virus strain D1701 was used to generate a ...

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Characterization of a Borna disease virus glycoprotein, gp18.

Characterization of a Borna disease virus glycoprotein, gp18.

... Isolation and characterization of a 14500 molecular weight protein from brains and tissue cultures persistently infected with Borna disease virus.. Sequence conservation in field and exp[r] ...

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Detection and Sequence Analysis of Borna Disease Virus p24 RNA from Peripheral Blood Mononuclear Cells of Patients with Mood Disorders or Schizophrenia and of Blood Donors

Detection and Sequence Analysis of Borna Disease Virus p24 RNA from Peripheral Blood Mononuclear Cells of Patients with Mood Disorders or Schizophrenia and of Blood Donors

... Borna disease virus (BDV) p24 RNA was detected in the peripheral blood mononuclear cells (PBMCs) of psychiatric patients and blood donors by nested reverse transcriptase PCR ...

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Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

... Background: Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral ...

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Borna Disease Virus RNA in Immunocompromised Patients in Southwestern France

Borna Disease Virus RNA in Immunocompromised Patients in Southwestern France

... Borna disease virus (BDV) is a neurotropic RNA virus with a wide host ...immunodeficiency virus (HIV)-infected and 80 therapeutically immunosuppressed ...

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Biochemical and functional analysis of the Borna disease virus G protein.

Biochemical and functional analysis of the Borna disease virus G protein.

... Borna disease virus (BDV) is a neurotropic virus that causes movement and behavioral disturbances in a wide range of warm-blooded hosts (18, 25, 30, 31, ...of Borna disease were ...

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Activation of Microglia by Borna Disease Virus Infection: In Vitro Study

Activation of Microglia by Borna Disease Virus Infection: In Vitro Study

... Neonatal Borna disease virus (BDV) infection of the rat brain is associated with microglial activation and damage to the certain neuronal ...purified virus nor BDV-infected neurons alone ...

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Characterization of the Nuclear Localization Signal of the Borna Disease Virus Polymerase

Characterization of the Nuclear Localization Signal of the Borna Disease Virus Polymerase

... Borna disease virus (BDV) is a nonsegmented negative-strand RNA virus that replicates and transcribes its genome in the nucleus of infected ...

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Detection of Borna Disease Virus (BDV) in Patients with First Episode of Schizophrenia

Detection of Borna Disease Virus (BDV) in Patients with First Episode of Schizophrenia

... including Borna Disease Virus (BDV) may play a role in transient or permanent neurological and behavioral ...of Borna virus has not been resolved outright yet, and based on published ...

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Characterization of the Borna disease virus phosphoprotein, p23.

Characterization of the Borna disease virus phosphoprotein, p23.

... Borna disease virus infection is diagnosed by the presence of serum antibodies reactive with the major viral proteins, p40 and p23. Although p40 and p23 are unrelated in amino acid sequence ...

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Borna Disease Virus Infects Human Neural Progenitor Cells and Impairs Neurogenesis

Borna Disease Virus Infects Human Neural Progenitor Cells and Impairs Neurogenesis

... Borna disease virus (BDV) is a highly neurotropic virus which persists in the central nervous system (CNS) of infected individu- als for their entire life ...RNA virus belonging to the ...

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Molecular biology of borna disease virus: prototype of a new group of animal viruses.

Molecular biology of borna disease virus: prototype of a new group of animal viruses.

... 7669-7675 0022-538X/94/$04.00+0 Copyright © 1994, American Society for Microbiology MINIREVIEW Molecular Biology of Borna Disease Virus: Prototype of a New Group of Animal Viruses JUAN C[r] ...

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Characterization of a glial cell line persistently infected with borna disease virus (BDV): influence of neurotrophic factors on BDV protein and RNA expression.

Characterization of a glial cell line persistently infected with borna disease virus (BDV): influence of neurotrophic factors on BDV protein and RNA expression.

... 1453-1460 0022-538X/93/031453-08$02.00/0 Copyright C 1993, American Society for Microbiology Characterization of a Glial Cell Line Persistently Infected with Borna Disease Virus BDV: Inf[r] ...

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