Breast Cancer Cell
A novel role for signal transducer and activator of transcription 5b (STAT5b) in β1 integrin mediated human breast cancer cell migration
... MDA-MB-231 breast cancer cell lines to serum, whereas knockdown of STAT5a has no effect (Figure ...on breast cancer cell ...T-47D breast cancer cell lines, ...
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Choosing the right cell line for breast cancer research
... to breast cancer cell lines to determine whether the molecular profi les observed in breast carcinomas are refl ected in cell line models of the ...of breast cancer ...
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Original Article MicroRNA-486-5p targets FGF9 and inhibits colorectal cancer proliferation, migration and invasion
... in breast cancer tissues and cell lines, and over-expression of miR-486-5p markedly suppressed breast cancer cell proliferation in vitro and in vivo, induced G0/G1 arrest, and ...
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IN VITRO ANTICANCER ACTIVITY OF Carica papaya (FRUITLESS TYPE) EXTRACT AGAINST HUMAN MCF-7 CELL LINE
... Breast cancer is the most common cancer in women ...of cancer where cells in the breast divide and grow without normal ...of breast cancer has doubled during the past 30 ...
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Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6
... BT-549 breast cancer cell line enhanced STAT5b transcriptional activity, as measured by a STAT5-specific luciferase ...Brk-positive breast cancer cell lines BT-20 and SKBr3, ...
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Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells
... luminal-like breast cancer cell line that has low AnxA1 expression, would induce a scattered ...increased cell scattering ...β-catenin-containing cell-cell junctions ...in ...
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<p>ST6GAL2 Downregulation Inhibits Cell Adhesion and Invasion and is Associated with Improved Patient Survival in Breast Cancer</p>
... of breast cancer cells via CD24, MMP2, and MMP9 directly or ...escape cell-mediated cytotoxicity and lysis by the host cellular immune ...increased breast cancer cell motility ...
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<p>miR-491-5p functions as a tumor suppressor by targeting IGF2 in colorectal cancer</p>
... -positive breast cancer tissues and cell lines, and overexpression of miIR-491-5p inhibited breast cancer cell proliferation via induction of cell cycle G1 arrest by ...
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Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells
... The cell survival fraction of four cancer cell lines – human gastric cancer cell line MGC803, human lung cancer cell line A549, human prostate cancer cell ...
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Microtubule-Associated Protein Mdp3 Promotes Breast Cancer Growth and Metastasis
... Breast cancer is the most prevalent cancer in women worldwide with a high mortality rate, and the identification of new biomarkers and targets for this disease is greatly ...and cell lines of ...
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Original Article MicroRNA-204 targets JAK2 in breast cancer and induces cell apoptosis through the STAT3/BCl-2/survivin pathway
... in cancer cell biological ...in breast cancer remain largely ...human breast cancer tissue and cultured breast cancer cell lines (MCF-7, ...in breast ...
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Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway
... in breast cancer and its underlying mechanisms are ...human breast cancer cases and the results showed that the expression of Nodal was significantly correlated with VM formation, tumor ...
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Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression
... many cancer types and indeed PI3Ks inhibitors are currently being tested in clinical ...human breast cancer cell lines and in human breast cancer ...regulates breast ...
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Abstract: Breast cancer is the most common cancer in women and distant site metastasis is the
... lung cancer recently ...tumor cell membranes that actively expel chemotherapeutic drugs from the ...in cancer is P-glycoprotein 1 (Pgp), also known as multidrug resistance protein 1 ...in ...
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USP17 Suppresses Tumorigenesis and Tumor Growth through Deubiquitinating AEP
... regulates cell proliferation through AEP ...inhibits breast cancer tumorigenesis through down-regulation AEP, we constructed AEP knockdown stable breast cancer cell lines in ...
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Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.
... + Breast Cancer-Specific Essential ...fects cell viability or potentiates the estrogen-independent growth of ER + breast cancer cells, we performed genome-wide CRISPR/ Cas9 knockout ...
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Breast Cancer Therapies Present and Future
... in breast cancer as well as other cancers ...of breast cancers are observed to have mutations, amplifications, deletions, methylations, and post-transla- tional modifications in this pathway ...
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LDL-cholesterol signaling induces breast cancer proliferation and invasion
... MDA MB 231 cells were seeded on 24-well plate and grown to confluence in DMEM, 10%FBS. Upon reaching confluence, the medium was replaced by DMEM, 1% FBSLF, for 24 h. Two-hundred-microliter tips were used to make a ...
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Flotillin 2 is associated with breast cancer progression and poor survival outcomes
... of breast cancer types ...of breast cancer is of great value in identifying high-risk patients who may benefit from more aggressive primary surgery, or adjuvant treat- ment following surgery, ...
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EMT and tumor metastasis
... the cancer progenitor cells, go through EMT to produce a metastatic form of ...in cancer cells as compared to that in normal cells ...in cancer, the en- hancer pattern alterations are more at par ...
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