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Breast cancer cell lines

Breast cancer cell lines: friend or foe?

Breast cancer cell lines: friend or foe?

... 38 breast cancer cell lines, and the extent to which these cell lines resembled uncultured tumours ...lished cell lines, that study also included some of the long ...

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MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

... of breast cancer ...both breast cancer cell lines (Figure ...of breast cancer cells in vivo, MDA-MB-231 and their shMST3 stable transfectant cells were inoculated ...

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Original Article Low expression of long noncoding RNA GAS6-AS1 as a novel biomarker of poor prognosis for breast cancer

Original Article Low expression of long noncoding RNA GAS6-AS1 as a novel biomarker of poor prognosis for breast cancer

... Background: Breast cancer is the most frequent cancer for women in the ...of breast cancer tissues and their matched nontumor adjacent tissues (NATs) as well as 4 breast ...

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Choosing the right cell line for breast cancer research

Choosing the right cell line for breast cancer research

... to breast cancer cell lines to determine whether the molecular profi les observed in breast carcinomas are refl ected in cell line models of the ...of breast cancer ...

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Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines

Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines

... Human breast cell lines have long served as models for a wide array of applications including the study of molecular, cellular, and biochemical mechanisms that regulate breast epithelial ...

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Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer

Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer

... to cancer pro- ...and breast cancer cell lines into functionally distinct subtypes, described as Luminal, Basal A, and Basal ...the cell lines were evaluated for invasive ...

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Cell Lines: An Invitro Model To Study Breast Cancer

Cell Lines: An Invitro Model To Study Breast Cancer

... established cell lines will continue to be used as models for breast ...novel cell lines, particularly those established from primary breast tumours and now available through ...

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AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

... in breast normal epithelial and cancer cell lines and detected AF1q in one of two immortalized breast normal epithelial cell lines (MCF10a) and in three of eight ...

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Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT

Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT

... across breast cancer subtypes [48], we hypothesized that Rab25 expression and function would be positively associated with progression of breast cancers with epithelial ...B breast cancers and ...

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USP17 Suppresses Tumorigenesis and Tumor Growth through Deubiquitinating AEP

USP17 Suppresses Tumorigenesis and Tumor Growth through Deubiquitinating AEP

... regulates cell proliferation through AEP ...inhibits breast cancer tumorigenesis through down-regulation AEP, we constructed AEP knockdown stable breast cancer cell lines ...

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Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

... many cancer types and indeed PI3Ks inhibitors are currently being tested in clinical ...human breast cancer cell lines and in human breast cancer ...regulates ...

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Q&A: What are exosomes, exactly?

Q&A: What are exosomes, exactly?

... in cancer biology. Exosomes from breast cancer cell lines, for example, have been shown to be enriched for miRNAs relative to nontumorigenic breast cell lines and ...

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Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway

Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway

... in breast cancer and its underlying mechanisms are ...human breast cancer cases and the results showed that the expression of Nodal was significantly correlated with VM formation, tumor ...

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Original Article Overexpression of long non-coding RNA HOTAIR enhances breast cancer radioresistance via RhoC-Akt pathway by targeting HOXD10

Original Article Overexpression of long non-coding RNA HOTAIR enhances breast cancer radioresistance via RhoC-Akt pathway by targeting HOXD10

... of breast cancer radiotherapy- the main regimen for inoperable and locally advanced breast ...on breast cancer and explore the possible underlying ...into cell line SKBR3 using ...

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Adenovirus type 5 E1A induced apoptosis in COX 2 overexpressing breast cancer cells

Adenovirus type 5 E1A induced apoptosis in COX 2 overexpressing breast cancer cells

... Our study had some limitations. For one thing, although we did confirm that all four E1A stable transfectants expressed E1A (Figure 1), the level of expression was not uniform among the cell lines. ...

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Flotillin 2 is associated with breast cancer progression and poor survival outcomes

Flotillin 2 is associated with breast cancer progression and poor survival outcomes

... from cell lines and primary tumor materials were extracted using Trizol reagent (Invitrogen, Carlsbad, CA, USA) according to the manufacturer’s in- ...primary breast tumors rela- tive to the paired ...

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Biotinylated xanthohumol: synthesis and in vitro

Biotinylated xanthohumol: synthesis and in vitro

... cancer cell lines: MCF-7 (breast cancer), MDA-MB-231 (breast cancer), HepG2 (liver. 291 [r] ...

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Investigation of anti cancer and migrastatic properties of novel curcumin derivatives on breast and ovarian cancer cell lines

Investigation of anti cancer and migrastatic properties of novel curcumin derivatives on breast and ovarian cancer cell lines

... ovarian cancer, which is de- livered by cancer stem cells that remain even after treatment [55, ...that cancer stem cells ex- pansion and characteristics lead to drug resistance [57, ...eliminate ...

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Multidrug resistance in breast and bladder cancer cell lines

Multidrug resistance in breast and bladder cancer cell lines

... membranes^^. This observation has led to other speculations about the removal of cytotoxics from the cell. Gervasoni hypothesises that the P-glycoprotein migrates with the recycling plasma membrane vesicles^^. ...

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Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepilone

Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepilone

... many cancer cell lines and xenografts resistant to micro- tubule inhibitors, and this may be associated with the primary or acquired resistance to tubulin-binding agents observed clinically in many ...

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