Breast Carcinomas
Original Article Phosphorylated mTOR expression correlates with poor outcome in early-stage triple negative breast carcinomas
... in breast can- cers [16, ...including breast, ovarian, colon, pancreatic, and gastric cancers [13, ...on breast cancer mainly pertain to breast cancers in ...invasive breast ...
8
Quantification of Microvessel Density in Breast Carcinomas Based on Immunohistochemistry
... The terminal duct- lobular unit is represents the secretory portion of the gland which is composed of lobule and the terminal ductule.The breast development depends on the close interaction between these ...
147
Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
... in breast carcinomas was correlated with (1) decreased survival and total vessel counts in highly vascularized tumour areas (Kato et al, 1997) and (2) diffuse tumour infiltration by macrophages (Lee et al, ...
5
Clinico-Pathological Study of Breast Carcinomas with ER, PR Studies.
... OF BREAST CARCINOMAS WITH ER, PR STUDIES’ under my guidance and supervision in partial fulfillment of the regulation laid down by the 'THE TAMILNADU DR MGR MEDICAL UNIVERSITY, CHENNAI - 32' for ...
109
Breast cancer stroma frequently recruits fetal derived cells during pregnancy
... country, breast carcinomas are the first or the second most common cancer occurring in pregnant women ...of breast cancer during pregnancy has a number of distinct ...in breast ...
8
No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer
... in breast carcinomas cancer or a panel of cancer cell lines, including ten breast cancer cell lines, making it unlikely that methylation of the promoter regions of these genes is responsible for ...
8
Clinicopathological, therapeutic and prognostic features of the triple negative tumors in moroccan breast cancer patients (experience of Hassan II university hospital in Fez)
... Triple-negative breast cancer (TNBC) is defined as a group of breast carcinomas that are negative for expres- sion of hormone receptors (ER, PR) and HER2, we can distinguish between two groups: ...
6
Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non carriers, and sporadic cases
... whether breast carcinoma is part of the LS tumor spectrum based on molecular characteristics of the individuals and ...compare breast carcinomas from mutation carriers to those from proven ...
11
BRCA promoter methylation in sporadic versus BRCA germline mutation related breast cancers
... distinguishing breast carcinomas from BRCA1 and BRCA2 germline mutation carriers (BRCA1/2-related breast carcinomas) and sporadic breast carcinomas using a recently developed ...
13
Immunotherapy of Cancer—A Historical Note
... We examined the possibility that the anti-estrogens, tamoxifen (TX) and toremifen (TO) interacted with the immune system. Indeed, both TX and TO stimulated cells mediated cytotoxicity reactions by various killer cells: ...
5
Breast cancer epithelial to mesenchymal transition: examining the functional consequences of plasticity
... with breast cancer have been demon strated for many of these ...of breast cancer patients has associated SNAI1 with tumor recurrence, while SNAI2 is associated with tumor recur- rence and metastasis ...in ...
13
Original Article Estrogen receptor (ER), progesterone receptor (PR), and HER2 expression pre- and post- neoadjuvant chemotherapy in primary breast carcinoma: a single institutional experience
... For HER2 IHC and HER2 FISH, no significant dif- ference in expression was found in this study in primary breast carcinomas between pre- and post- neoadjuvant treatment specimens. The stability of HER2 ...
7
Frequent loss of endothelin 3 (EDN3) expression due to epigenetic inactivation in human breast cancer
... with breast tumour ...in breast cancer ...in breast cancer biology and that EDN3, unlike other members of the ET-axis, may represent a novel tumour suppressor gene in the human mammary ...cancerous ...
18
Cytoplasmic location of factor inhibiting hypoxia inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer
... in breast carci- noma, we have examined the expression of FIH-1 in a large characterized series of breast carcinomas and have correlated this with standard clinicopathological parameters and various ...
10
Elevated mammaglobin (h MAM) expression in breast cancer is associated with clinical and biological features defining a less aggressive tumour phenotype
... human breast cancer specimens. They studied 35 breast carcinomas of different histological varieties, and found h-MAM to be overexpressed (at least 10-fold relative to normal breast tissue) in ...
6
Role of the Cdc25A phosphatase in human breast cancer
... poor survival, while Ki67 had no predictive value of survival status (18). In the residual 144 cases used here, stratification according to p27 status showed a trend toward predicted survival but was not signifi- cant. A ...
10
LIN7A is a major determinant of cell polarity defects in breast carcinomas
... invasive carcinomas of no special type; IMPC: invasive micropapillary carcinoma; LIN7A: lin-seven A; PALS1: protein associated with lin-seven 1; PAR4: partitioning-defective 4; ROC: receiver operating ...
10
Polarity gene alterations in pure invasive micropapillary carcinomas of the breast
... In our comprehensive genomic analysis of IMPCs of the breast, we identified numerous genomic alterations and somatic mutations, but no recurrent fusion gene. We demonstrate that IMPC is associated with a specific ...
15
Estrogenic microenvironment generated by organochlorine residues in adipose mammary tissue modulates biomarker expression in ERα positive breast carcinomas
... of breast carcinoma patients, adverse effects have been sug- gested by Demers and colleagues [13], Hoyer and colleagues [14] and Muscat and colleagues ...in breast carcinoma patients that have been ...
9
Original Article Determination of whole transcription profiles and specific pathways in invasive ductal breast carcinoma
... Abstract: Breast cancer is the most common cancer affecting women worldwide including ...ductal breast carcinoma (IDC) obtained by oligonucleotide microarray should lead to a better understanding of the ...
9