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Bronchial epithelial cells

Glutathione-S-transferase M1 regulation of diesel exhaust particle-induced pro-inflammatory mediator expression in normal human bronchial epithelial cells

Glutathione-S-transferase M1 regulation of diesel exhaust particle-induced pro-inflammatory mediator expression in normal human bronchial epithelial cells

... airway epithelial cells play in the pathogenesis of airway inflammation, we manipulated GSTM1 levels in primary human bronchial epithelial cells (HBEC) from human volunteers with GSTM1 ...

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Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells

Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells

... on epithelial biology with an effect on inflammation and ...primary epithelial cells ...NCI-H292 cells retain their original mucoepidermoid characteristics with nearly diploid chromosome ...

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TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells

TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells

... from bronchial epithelial cells using the RNeasy plus mini kit (Qiagen, Valencia, CA, USA) with DNase treatment, followed by cDNA synthesis using the First-Strand cDNA Synthesis kit (GE Healthcare, ...

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Altered microRNA expression profile during epithelial wound repair in bronchial epithelial cells

Altered microRNA expression profile during epithelial wound repair in bronchial epithelial cells

... during epithelial wound repair is the expression of small non-coding RNA molecules termed microRNAs (miRNAs) ...in epithelial cell proliferation and differentiation ...lung epithelial progenitor ...

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The innate immune response of equine bronchial epithelial cells is altered by training

The innate immune response of equine bronchial epithelial cells is altered by training

... equine bronchial epithelial cells (EBEC) in vitro and to explore EBEC innate immune responses in trained ...horses. Bronchial epithelial biopsies were taken from 6 adult horses during ...

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Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines

Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines

... of bronchial epithelial cells in bronchial brush biopsies harvested from healthy subjects by selecting data of interest from a broad mRNA analyses of the COSMIC cohort material ...these ...

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Anti-inflammatory effects of antibacterials on human bronchial epithelial cells

Anti-inflammatory effects of antibacterials on human bronchial epithelial cells

... immune cells, NHBE cells (normal human bronchial epithelial cells) and immortalised respiratory cell lines ...in cells of the immune ...

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Bilateral Entry and Release of Middle East Respiratory Syndrome Coronavirus Induces Profound Apoptosis of Human Bronchial Epithelial Cells

Bilateral Entry and Release of Middle East Respiratory Syndrome Coronavirus Induces Profound Apoptosis of Human Bronchial Epithelial Cells

... permissive cells of different mammalian species ...airway epithelial cells (HAEC) and releases infectious prog- eny virus predominantly through the apical surface, it seems to be more vulnerable than ...

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β2 adrenergic agonist suppresses eosinophil-induced epithelial-to-mesenchymal transition of bronchial epithelial cells

β2 adrenergic agonist suppresses eosinophil-induced epithelial-to-mesenchymal transition of bronchial epithelial cells

... of epithelial cells and eosinophils up-regulates the expression of integrins on eosinophils and ICAM-1 and VCAM-1 on epithelial cells, and that inhibition of integrin-mediated cell-contact ...

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Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

... primary bronchial epithelia derived from CF patients as evidenced by electrophysiological and biochemical ...human bronchial epithelial cells from 3 different F508del homo- zygous subjects by ...

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The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer

The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer

... human bronchial epithelial BEAS2B cells and measured lactate and glucose concentrations in culture supernatant after 24 ...CSC-treated cells in vitro raises questions about the possible role ...

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Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients

Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients

... in bronchial epithelial cells derived from COPD subjects, demonstrating that these cells are undergoing EMT ...normal bronchial epithelial cells responded to cell culture ...

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Modulation of airway inflammation in cystic fibrosis  In vivo suppression of interleukin 8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor

Modulation of airway inflammation in cystic fibrosis In vivo suppression of interleukin 8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor

... Based on the knowledge that neutrophil elastase (NE) in cystic fibrosis (CF) epithelial lining fluid (ELF) can induce human bronchial epithelial cells to express the gene for interleukin 8 ...

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In vitro primary cell culture as a physiologically relevant method for preclinical testing of human oncolytic adenovirus

In vitro primary cell culture as a physiologically relevant method for preclinical testing of human oncolytic adenovirus

... primary cells in in vitro cell culture to test whether Ad[I/PPT-E1A] replication is limited only to the prostate target cells by assessing the specificity and sensitivity of Ad[I/PPT-E1A] replication and ...

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The adipocyte fatty acid–binding protein aP2 is required in allergic airway inflammation

The adipocyte fatty acid–binding protein aP2 is required in allergic airway inflammation

... of epithelial cells with the Th2 cytokines IL-4 and ...non-hematopoietic cells, most likely bronchial epithelial cells, as the site of action of aP2 in allergic airway ...

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A review of mammalian toxicity of ZnO nanoparticles

A review of mammalian toxicity of ZnO nanoparticles

... human bronchial epithelial cell line (BEAS-2B) and human alveolar adenocarcinoma cell line (A549) are the two human cell lines representing the airways that are used most ...types, bronchial ...

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Ligation of protease activated receptor 1 enhances αv
               β6
               integrin–dependent TGF β activation and promotes acute lung injury

Ligation of protease activated receptor 1 enhances αv β6 integrin–dependent TGF β activation and promotes acute lung injury

... airway epithelial (normal human bronchial epithelial) cells were obtained commercially from Cambrex, and the TML epithelial reporter cells stably expressing firefly luciferase ...

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p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice

p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice

... inflammatory cells and airway smooth muscle, 3) release of degradative enzymes (eg, MMPs) and growth factors, 4) control of the production of interferon-γ from CD4 positive andCD8 positive T cells, and ...

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Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels

Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels

... contaminant of cigarettes, causes down-regulation of the expression and function of the CFTR chloride channel [9]. Many metals have been shown to be present in cigarette smoke, including aluminum, cadmium, chromium, cop- ...

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Regional heterogeneity in response of airway epithelial cells to cigarette smoke

Regional heterogeneity in response of airway epithelial cells to cigarette smoke

... airway epithelial cells from different sites in the lungs have not been fully ...airway epithelial cells (SAECs) and normal human bronchial epithelial cells (NHBEs) were ...

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