bronchial epithelium
Bronchial epithelium in children: a key player in asthma
... samples: bronchial explants, endobronchial biopsies and bronchial ...pseudostratified bronchial epithelium similar to the epithelium observed on the initial endobronchial biopsies ...
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Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
... immunohistochemistry. Bronchial epithelium showed strong MBD2 protein staining in lung tissues of non-smokers on immunohistochemistry (Figure ...the epithelium were markedly decreased in patients ...
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Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD
... from bronchial brushings by bronchoscopy using a fiberoptic bronchoscope according to standard guidelines ...from bronchial brushings in 2 smoking and 3 non-smoking ...from bronchial brushings when ...
11
Diesel exhaust exposure enhances the expression of IL 13 in the bronchial epithelium of healthy subjects
... Summary Epidemiological studies have demonstrated adverse health effects of environmental pollution. Diesel exhaust (DE) is an important contributor to ambient particulate matter pollution. DE exposure has been shown to ...
5
Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium
... airway epithelium after DE exposure, by analyses of archived human bronchial biopsies ...the bronchial epithelium, accompanied by a pro- nounced neutrophil influx in the bronchial ...
9
PM2.5 induces autophagy-mediated cell death via NOS2 signaling in human bronchial epithelium cells
... In our study, we demonstrated that PM2.5 rapidly induced autophagosome formation and subsequently cell death in human bronchial epithelium cells. We further found that PM2.5 specifically induced NOS2 ...
8
Multiwalled carbon nanotubes induce altered morphology and loss of barrier function in human bronchial epithelium at noncytotoxic doses
... human bronchial epithelial cells exposed in submerged culture to noncytotoxic doses of MWCNTs over 7 ...lung epithelium, which can result in a harmful reduction in barrier function over time, even at ...
13
Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37
... induced reduction in TEER was lost at 48 h after CSE ex- posure with or without retreatment with 20 μg/ml LL-37 at 24 h after exposure (Additional file 5). Treatment with LL-37 in combination with 10 nM BUD had no ...
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Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients
... in bronchial and lung ...in bronchial epithelium of COPD samples vs ...of bronchial brushing-derived transcriptomic confirmed the selective decrease of AUF-1 in COPD vs controls and revealed ...
18
Organ tropism of Sendai virus in mice: proteolytic activation of the fusion glycoprotein in mouse organs and budding site at the bronchial epithelium.
... Recently, we isolated a host range mutant of Sendai virus, * F1-R, which underwent multiple cycles of replication in several tissue culture cells, attributed to the proteolytic cleavage [r] ...
8
Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro
... XZ-projections also allowed for the recognition of non- phagocytosed NP for comparative purposes (encircled, Figure 2). Furthermore, we reconstructed the apical part of the triple cell co-culture by imaging software, ...
10
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft ferroptosis in bronchial epithelium
... As an opportunistic bacterial pathogen, P. aeruginosa has acquired multiple adaptive genes favoring the highly adaptive phe- notypes required to thrive and outcompete many other species in the highly proinflammatory ...
16
Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium
... human bronchial epithelial; MTeCs, mouse tracheal epithelial cells; CCK8, cell counting kit 8; neC-1, necrostatin-1; DMsO, dimethyl sulfoxide; rIP, receptor-interacting protein; seM, standard error of the ...
11
Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation
... bronchial segment, and 5 mL control (normal saline) was instilled in a contralateral lower lobe bronchial segment. Photographs were taken of the segments instilled, to guide subsequent bronchoscopy as ...
49
Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung
... 1A. Epithelium of a bronchus is positive for claudin-1 (ar- ...1D-1E. Epithelium of bronchioles is strongly positive for claudin-4 (ar- ...of bronchial epithelium are positive for ...1G. ...
10
1181.pdf
... Based on the fact that the observed lung cancers among uranium miners appear to occur primarily in the TB region (Mc80), the basal cells of the bronchial epithelium are regarded as the most radiosensitive ...
72
The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus
... in bronchial epithelial cells of small airways collected from the same site in patients infected with ...HIV bronchial epithelium and to determine whether the bacterial microbiome of the HIV ...
10
CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers
... in bronchial epithelium from endobronchial biopsies taken from an independent cohort of subjects undergoing autofluorescence bronchoscopy, and tested for correlation between CC16 immunostaining intensity ...
8
Induction of immune tolerance and reduction of aggravated lung eosinophilia by co-exposure to Asian sand dust and ovalbumin for 14 weeks in mice
... OVA alone causes a slight proliferation of goblet cells and an infiltration of eosinophils and lymphocytes, and slight thickening of the airway wall, which are the path- ology correlatives seen in human asthma. The ...
10
Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD
... the epithelium [5-8]. In con- trolled situations, the bronchial epithelium represents the first line of defense and protects the lung by acting as a physicochemical barrier of the ...way ...
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