Bulk Drugs
A Validated Stability Indicating LC Method for Amlexanox in Bulk Drugs
... The Stability Indicating RP-LC method developed for quantitative determination of amlexanox in bulk drugs is precise, accurate and specific. The method was com- pletely validated showing satisfactory data ...
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Spectrophotometric Quantitative Estimation of Lornoxicam and Paracetamol in Bulk Drugs and Dosage Form
... optimum accuracy, precision, time, economy, and sensitivity. The mean percent label claims in tablet were found by the proposed methods 100.69± 1.84%, 99.53±0.55% (Method I) and 98.97±1.150%, 99.38±0.458% (Method II) for ...
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DEVELOPMENT AND VALIDATION OF A SUPERCRITICAL FLUID LIQUID CHROMATOGRAPHIC METHOD FOR DETERMINATION OF ENANTIOMERIC PURITY OF ATORVASTATIN IN BULK DRUGS AND PHARMACEUTICALS
... C. Effects of methanol and temperature on enantioselectivity and resolution of the enantiomers were evaluated. For quantitative determinations using UV detector at 240nm. Polarimetric detector was used for identification ...
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Development and Validation of a Stability Indicating RP HPLC Method for Determination of Darifenacin Hydrobromide in Bulk Drugs
... A simple and rapid isocratic stability-indicating reversed phase high-performance liquid chromatography me- thod for the determination of DRF and its process-related impurities was developed and validated. Various forced ...
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A Stability Indicating U HPLC Method for Milnacipran in Bulk Drugs and Pharmaceutical Dosage Forms
... in renal impairment using HPLC and GCMS [12], Acute electrophysiological effects of intravenous Milnacipran, a new antidepressant agent using HPLC [13]. GC method also reported in literature for the determination of Mil- ...
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Synthesis, characterization and pharmacological screening of various impurities present in Opipramol, Pargeverine and Propiverine bulk drugs
... of bulk drugs like opipramol, pargeverine and propiverine were synthesized and characterized by various analytical techniques such as TLC, FTIR, 1 H-MNR, FABMS and Elemental ...opipramol bulk drug ...
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CHEMOMETRICS ASSISTED RP-HPLC METHOD DEVELOPMENT FOR THE SEPARATION OF SECOND GENERATION TYROSINE KINASE INHIBITORS IN BULK DRUGS AND PHARMACEUTICAL FORMULATIONS
... The present study describes a newly developed, optimized and validated isocratic RP-HPLC method for the separation of two tyrosine kinase inhibitors (Dasatinib-DST and Nilotinib-NLT) with Methyl paraben-MPB as internal ...
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STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS DETERMINATION OF LEVOCETIRIZINE HYDROCHLORIDE AND MONTELUKAST SODIUM AS BULK DRUGS AND IN TABLET DOSAGE FORM
... resulting solution was applied on TLC plate and developed under optimized chromatographic conditions. Same procedure was repeated for MONT to get final concentration 800 ng band -1 applied on the TLC plate. Both ...
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SIMULTANEOUS DETERMINATION OF ETODOLAC AND PARACETAMOL IN BULK DRUGS AND PHARMACEUTICAL FORMULATION BY HPTLC DENSITOMETRIC AND UV DERIVATIVE SPECTROPHOTOMETRY METHODS
... standard drugs at three different concentrations in the linearity range for three times on the same ...standard drugs at three different concentrations in the linearity range of drugs for two days ...
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SPECTROPHOTOMETRIC QUANTITATIVE ESTIMATION OF HYDROCHOLOROTHIAZIDE AND LISINOPRIL IN BULK DRUGS AND PHARMACEUTICAL DOSAGE FORM
... in bulk and in marketed combined tablet dosage ...both drugs in different concentration ...these drugs was found to be close to ...two drugs in bulk & combined dosage ...
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Development and Validation of New RP HPLC Method for the Estimation of Alfuzosin Hydrochloride in Bulk and Tablet Dosage Form
... A reverse phase high performance liquid chromatographic method (HPLC) has been developed for the estimation of Alfuzosin hydrochloride (ALH) in the pharmaceutical formulation using RP-C18 column. The mobile phase ...
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Development and validation of HPTLC method for the simultaneous analysis of gatifloxacin and ketorolac tromethamine in eye drops
... High-performance thin-layer chromatography (HPTLC) is a form of thin-layer chromatography (TLC) that provides superior separation power using optimized coating material, novel procedures for mobile-phase feeding, layer ...
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“DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING LC METHOD FOR SIMULTANEOUS ANALYSIS OF DROTAVERINE HYDROCHLORIDE AND DICLOFENAC POTASSIUM AND ITS APPLICATION FOR FORMULATION ANALYSIS” by Vishnu Choudhari, Archana M. Ambekar, Kunal Ingale, India.
... Simple, sensitive, selective, precise stability indicating chromatographic methods for determination of Drotaverine Hydrochloride and Diclofenac Potassium from pharmaceutical tablets were developed and validated as per ...
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SPECTROPHOTOMETRIC DETERMINATION OF TERBINAFINE HCl, TELMISARTAN AND RAMIPRIL THROUGH REDOX REACTIONS USING CERIC SULPHATE AND CERIC SULPHATE-CHROMATROPE 2R
... in bulk drugs and in their dosage forms using ceric (IV) sulphate and ceric (IV) sulphate-chromatrope 2R as ...to drugs in acid medium, followed by determination of the decrease in absorbance ...
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A NEW VALIDATED RP HPLC METHOD FOR THE DETERMINATION OF METFORMIN HCL AND EMPAGLIFLOZIN IN ITS BULK AND PHARMACEUTICAL DOSAGE FORMS
... 17. N. Padmaja, G. Veerabhadram , Development and validation of analytical method for Simultaneous estimation of Empagliflozin and Linagliptin in bulk drugs and combined dosage forms using UV-visible ...
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REVERSED PHASE LIQUID CHROMATOGRAPHY WITH MASS DETECTION AND NMR CHARACTERIZATION OF SITAGLIPTIN DEGRADATION RELATED IMPURITIES
... its bulk drugs, included development of a stability- indicating reverse-phased liquid chromatographic method and its validation for the estimation of degradation related impurities ...
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DEVELOPMENT AND VALIDATION OF A NOVEL STABILITY INDICATING RP HPLC METHOD FOR THE DETERMINATION OF EMPAGLIFLOZIN IN BULK AND PHARMACEUTICAL DOSAGE FORM
... Handful clinical trials were reported in the literature for Empagliflozin 11-15 . But scarcely reports have been found for RP-HPLC determination of Empagliflozin in pharmaceutical preparations. In this paper, we ...
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Journal of Applied Pharmaceutical Science
... determination of the cited drugs in bulk and in dosage forms available in the Egyptian market. The proposed method was designed based on firstly, the presence of free primary amino group in the structure of ...
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ANALYTICAL DEVELOPMENT AND FORMULATION OF RAMIPRIL AND HYDROCHLOROTHIAZIDE IN COMBINATION WITH SELECTIVE EXCIPIENTS
... of bulk drugs with excipients and quantification of Ramipril and Hydrochlorothiazidefrom its tablet dosage ...of bulk drugs with excipientsthecompatabilitystudieswere studied and the presence ...
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Stability Indicating Method Development and Validation of Tenofovir Disoproxil Fumarate in Bulk and its Tablet Dosage Form by HPTLC.
... ABSTRACT - A novel stability – indicating high performance thin layer chromatography HPTLC assay method was developed and validated for quantitative determination of Tenofovir Disoproxil Fumarate in bulk ...
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