C2C12 cells
Unveiling novel genes upregulated by both rhBMP2 and rhBMP7 during early osteoblastic transdifferentiation of C2C12 cells
... pre-myoblastic C2C12 cells during 24 h of treatment with rhBMP2 and ...precursor cells into osteoblasts: Hoxc8, Glis1, Glis3, Ecsit, PKCd, LrP6, Dvl1, Grn, BMP1, Ltbp2, Plod1, Htra1 and ...
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Investigation of interactions between poly-L-lysine-coated boron nitride nanotubes and C2C12 cells: up-take, cytocompatibility, and differentiation
... the cells, but provided no information on the nature of the mechanism responsible for this ...of cells incubated for 1 h in a medium containing 5 µ g/mL of Qdot-labelled BNNTs: internalization occurred as ...
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Upregulation of FNDC5 gene expression in C2C12 cells after single and combined treatments of resveratrol and ATRA
... myoblasts, C2C12 cells, were seeded in 6-well plastic plates and cultured in DMEM ...study, C2C12 myotubes were treated with different concentrations of Res and ATRA for 12 ...
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Original Article SIRT1 regulates C2C12 myoblast cell proliferation by activating Wnt signaling pathway
... muscle cells in vivo and in vitro has not been reported ...in C2C12 cells model, and that the stimulating effect is both approximate- ly in dose-dependent manner and time-depen- dent ...muscle ...
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<p>Effect of <em>Rubus anatolicus</em> Leaf Extract on Glucose Metabolism in HepG2, CRI-D2 and C2C12 Cell Lines</p>
... and C2C12 cells were cultured in 6-well plate (5×10 3 and 3 × 10 5 cells/mL, respectively), When cells reached con fl uence, the mediums were replaced by DMEM/RPMI 1640 supplemented with ...
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A fractionation method to identify qauntitative changes in protein expression mediated by IGF-1 on the proteome of murine C2C12 myoblasts
... IGF-1-stimulated cells (Figure 4B, top panels) confirm the decreased expression after IGF-1 treatment identified from the mass spectroscopic ...of C2C12 cells activates MAP kinase and PI ...
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Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathway
... This study examined the role of CSN3 in skeletal muscle differentiation and proliferation. CSN3 is subunit 3 of CSN complex, a highly conserved multifunctional com- plex composed of 8 subunits (CSN1-CSN8) present in ...
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3,4-DHPEA-EA Peracetylated (3,4-DHPEA-EA(P)) Attenuates H 2O -Mediated Cytotoxicity in C2C12 Myocytes via Inactivation of p-JNK/p-c-Jun Signaling Pathway
... in C2C12 cells, as it is able to reduce intracellular levels of ROS resulting in inhibition of cell death and atrophy, conditions observed under increased oxidative ...
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Oleuropein aglycone peracetylated (3,4-DHPEA-EA(P)) attenuates H 2O -mediated cytotoxicity in C2C12 myocytes via inactivation of p-JNK/p-c-Jun signaling pathway
... of C2C12 proceeds via the JNK/c-Jun ...of C2C12 cells; because MyoD mRNA levels and the differentiation process are restored with 3,4-DHPEA-EA(P) after ...
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Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation
... Micropatterned C2C12 myotubes develop more sarcomeres than those grown on other substrates In this study, we compared C2C12 myotubes cultured on three different ...community. Cells were analyzed at ...
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miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation
... 450a-1, a non-myogenic miRNA which does not have overlapping predicted targets with miR-1/206. Luciferase quantification showed that this miRNA did not cross- react with the selected SR 3′ UTRs or with 3′ UTRs car- rying ...
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Effects of Rhizome Extract of Dioscorea Batatas and Its Active Compound, Allantoin, on the Regulation of Myoblast Differentiation and Mitochondrial Biogenesis in C2C12 Myotubes
... in C2C12 cells and mitochondrial biogenesis through upregulation of the mitochondrial transcription factors, PGC1α, TFAM, NRF1, and SIRT1 via activation of the AMPK/ACC signaling ...
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Sargassum horneri methanol extract rescues C2C12 murine skeletal muscle cells from oxidative stress induced cytotoxicity through Nrf2 mediated upregulation of heme oxygenase 1
... SHME upregulates HO-1 and Nrf2 protein expression Because HO-1 is an important component of cellular defenses against oxidative stress, we assessed whether non-cytotoxic concentrations of SHME would affect HO-1 protein ...
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Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines
... Briefly, C2C12 cells (0.4 × 10 4 cells/100 μL) were seeded in a 96-well micro- plate and treated with amygdalin at concentrations of 0– 25 μM for 24 or 48 ...
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Plastic Additives Decrease Agrin Induced Acetylcholine Receptor Clusters and Myotube Formation in C2C12 Skeletal Muscle Cell Culture
... the C2C12 cell culture model to examine how exposure to BPA or DEHP affects two aspects of skeletal muscle development, the fusion of myob- lasts into myotubes and agrin-induced clustering of acetylcholine ...
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Clenbuterol Induces Cell Cycle Arrest in C2C12 Myoblasts by Delaying p27 Degradation through β-arrestin 2 Signaling
... in C2C12 cells incubated with 100 µM CLB for 1 ...synchronized cells were treated with 100 µM CLB for 12 h, probed with anti-p27 antibody, and stained with Alexa 594-conjugated secondary antibody ...
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Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12
... after cells were loaded with PA or with PA and unsaturated fatty acids (Figure ...of C2C12 with PA induced obviously DNA cleavage, and AA but not ETYA pre- vented more effectively PA-caused DNA laddering ...
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MiR-696 Regulates C2C12 Cell Proliferation and Differentiation by Targeting CNTFRα
... during C2C12 cell proliferation and differentiation (Figure 1F and G), which indicated that miR-696 might have a negative function in skel- etal muscle ...of C2C12 cells (Figure 2B-2E and Figure ...
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The Effect of Curcumin on GLUT4 Gene Expression as a Diabetic Resistance Marker in C2C12 Myoblast Cells
... Mouse C2C12 myoblasts were grown in Dulbecco’s Modified Eagle Medium (DMEM ...of C2C12 cells during 4 days to myotubes, cells were treated separately in the presence of insulin (100 nM), ...
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MiR-690, a Runx2-targeted miRNA, regulates osteogenic differentiation of C2C12 myogenic progenitor cells by targeting NF-kappaB p65
... of C2C12 cells into osteoblastic ...suppressor cells (MDSCs) and manipu- lates MDSC activity by repressing transcription factor CCAAT/enhancer-binding protein α in inflammatory diseases as well as ...
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