C6-glioma cells
Effects of quercetin nanoliposomes on C6 glioma cells through induction of type III programmed cell death
... of C6 glioma cells is involved in mediating ROS accumulation induced by ...QUE-NL. C6 glioma cells were treated with the indicated concentration of NL of quercetin (QUE-NL) for ...
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Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester–induced apoptosis in C6 glioma cells
... Three mammalian isoforms of neutral sphingomyeli- nase (N-SMase) have been cloned to date. N-SMase is membrane-bound and Mg 2+ -dependent. Acidic sphingo- myelinase (A-SMase) has three isoforms, an endosomal lysosomal ...
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Crocin induced apoptosis through p53-dependent pathway in C6 glioma Cells
... in C6 glioma ...[15]. Glioma tumors retain wild type p53; hence the ability to maintain the tumor phenotype depends on down regulated expression of p53 ...in C6 glioma cells ...
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Effects of ginsenosides Re and Rg3 on intracellular redox state and cell proliferation in C6 glioma cells
... of C6 glioma cells treated with Re and Rg3 was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) ...Briefly, cells were cultured in 96-well plates and ...
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Sensitization of rat C6 glioma cells to ionizing radiation by porphyrins
... on C6 glioma cells in the absence of light, the attached cells were washed three times with ...The cells were incubated at 37 °C in a 5% CO 2 environment respectively for 24 h and 18 ...
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Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells
... mechanisms of IL-1b-induced IL-6 release from C6 cells. IL-1b binds its receptor, which associates with IL- 1 receptor-accessory proteins to initiate an intracellular signaling [11-13]. NFB and the MAP ...
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Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma
... statins, C6 glioma cells were pre-administered 1 mM MVA, 10 μ M FPP, 10 μ M GGPP, 300 μ M squalene, 30 μ M isopentenylade- nine, 30 μ M dolichol, and 30 μ M ...
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CALCIUM MODULATORY EFFECTS OF CROCIN FROM SAFFRON (CROCUS SATIVUS L.) IN C6 GLIOMACELLS
... in C6 glioma cells by two different ...in C6 glioma cells or ...in glioma growth, proliferation and development it was imperative to evaluate its effect on calcium levels ...
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Immune reactivity in the nervous system: modulation of T lymphocyte activation by glial cells
... Astrocytes present myelin basic protein to encephalitogenic T cell lines.. prostaglandin E and an interleukin-1 like-factor by astrocytes and C6 glioma cells.[r] ...
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Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation
... on C6 glioma cells in vitro and in vivo. DCA inhib- ited C6 glioma cell proliferation, induced C6 cell apoptosis, and arrested C6 cells in S ...of C6 ...
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Topographical control of cell cell interaction in C6 glioma by nanodot arrays
... glial cells had much better cell spreading and adhesion when grown on larger micro-pillar spacing ...in C6 glioma cells [4] and upregulated the expression levels of communication-related ...
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Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction
... Glioblastomas are resistant to many kinds of treatment, including chemotherapy, radiation and other adjuvant therapies. As 2 O 3 reportedly induces ROS generation in cells, suggesting it may be able to induce ...
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Polymer Delivery of Hydroxycamptothecin against C6 Glioma
... The C6 glioma model was used as a brain tumor model here [13]. C6 glioma cells were harvested by trypsiniza- tion, pelleted by centrifugation, and resuspended for intracranial implant, ...
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Synthesis and characterization of Agiopep-2 anchored PEGylated poly propyleneimine dendrimers for targeted drug delivery to glioblastoma multiforme
... The present study was aimed at developing and exploring the use of Angiopep-2 anchored PEGylated Poly propyleneimine (PPI) dendrimers for targeted delivery of paclitaxel to the brain glioma. PPI dendrimers were ...
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Modulation of inducible nitric oxide synthase expression by sumoylation
... rat C6 glioma cells, NOS2 induction by over-expression of MAPKs was blocked by a dominant negative form of C/EBPβ ...muscle cells induction of NOS2 was accompanied by binding of C/EBPβ to the ...
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Activation of C6 glioblastoma cell ceruloplasmin expression by neighboring human brain endothelia-derived interleukins in an in vitro blood-brain barrier model system
... the cells were grown to confluency in their respective orientations, the media in the basal (bottom) chamber was switched to RPMI 1640 minus serum to mimic the interstitial fluid of the ...brain. Cells were ...
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Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury
... reduction in GLT-1 expression in the frontal cortex by neonatal DEX treatment. However, this finding is in con- trast with observations made in a previous study, which reported that DEX provokes an increase of GLT-1 ...
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Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells
... TNF-a-induced IL-6 release is dependent on the IB- NFB pathway [4]. Several sites in the N-terminal Rel homology domain, including Ser 276, or in the C termi- nus transactivation domain region play a pivotal role in the ...
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Strategies of temozolomide in future glioblastoma treatment
... study, which also used the emulsifying solvent evaporation method, superparamagnetic iron oxide was incorporated into the polysorbate 80-coated PLGA nanoparticles. There was no burst release in this preparation and 90% ...
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Magnetic resonance imaging of glioma with novel APTS coated superparamagnetic iron oxide nanoparticles
... the cells were trypsinized, centrifuged, and washed three times with PBS ...the C6 glioma cells were incubated with PBS buffer for 4 ...million C6 glioma cells (10 μL) ...
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